- Organotypic Culture of Organ of Corti with Floating Drop Method from Newborn Rat
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Cho CG, Chung JW, Kim HJ, Lee KS
- KMID: 1559724
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Jul;41(7):823-829.
BACKGROUND AND OBJECTIVES: Organotypic culture of organ of Corti maintains the basic organization of the spiral lamina and can conserve several factors responsible for the neuronal growth of the nervous... -
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- Light and Scaning Electromicroscopic Study on the Experimental on the Experimental Endolymphatic Hydrops in Guinea Pigs
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Oh SH, Jung HW, Kang BS, Kwon TK, Kim CS
- KMID: 1920896
- Korean J Otolaryngol-Head Neck Surg.
- 1997 Dec;40(12):1715-1721.
BACKGROUND: Despite numerous investigations, the pathogenesis of Meniere's disease is uncertain. Endolymphatic hydrops (ELH) has been the main histologic finding of Meniere's disease. Experimentally induced ELH in animal model has... -
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- Measurement of the Mechanical Deformation of Organ of Corti in a Model of Acute Endolymphatic Hydrops
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Lee SH, Kalinec F
- KMID: 2155057
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2016 Feb;59(2):110-119.
- doi: 10.3342/kjorl-hns.2016.59.2.110
BACKGROUND AND OBJECTIVES: Endolymphatic hydrops has been considered as an important histologic substrate of Meniere's disease. A permanent displacement of basilar membrane (BM) by increased endolymphatic pressure has been thought... -
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- Noise-Induced Hearing Loss
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Shim HJ
- KMID: 1793736
- Hanyang Med Rev.
- 2015 May;35(2):84-91.
- doi: 10.7599/hmr.2015.35.2.84
Noise-induced hearing loss (NIHL) is the second most common cause of permanent hearing impairment after age-related hearing loss. NIHL is influenced by environmental and genetic factors and the effects of... -
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- Effect of nicotine on the structure of cochlea of guinea pigs
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Abdel-Hafez AMM, Elgayar SA, Husain OA, Thabet HS
- KMID: 1882591
- Anat Cell Biol.
- 2014 Sep;47(3):162-170.
- doi: 10.5115/acb.2014.47.3.162
Smoking has been positively associated with hearing loss in human. However, its effect on the cochlea has not been previously evaluated. Aim of work is to investigate the effect of... -
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- Morphological Change of Mouse Inner Ear Hair Cells after Noise Exposure
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Lee SK, Kang HH, Gong MK, Lee KS, Chung JW
- KMID: 2276457
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Aug;48(8):967-974.
BACKGROUND AND OBJECTIVES: Mechanism of inner ear hair cell distortion after noise exposure has been well described. The present study was designed to determine the response to the auditory system... -
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- Dose-response Relationship of Morphologic Changes by Cisplatin and Radiation in Guinea Pig Cochleas
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Byun SW, Kim CD, Chung JW, Kim CS
- KMID: 2274425
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Jun;41(6):712-718.
BACKGROUND AND OBJECTIVES: Cisplatin or radiation have been widely used in the treatment of patients with head and neck cancers. However, their adverse effects such as ototoxicity and nephrotoxicity are... -
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- The Morphological Changes of the Cochlea in the Guinea Pig after Single Blast Wave Stimulation
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Cho CS, Park KY, Kim JY, Kim JW, Lee GW, Lee CH, Lee BK
- KMID: 2141374
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Sep;45(9):839-845.
BACKGROUND AND OBJECTIVES: The mechanism of the noise damage to the cochlea is not fully understood in spite of many studies. The morphological changes in a noise stimulated model show... -
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- Cochlear Pathology in Experimental Otitis Media with Effusion ofGuinea Pig Caused by Endotoxin
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Jung HH, Kim YH, Sung TH, Jung DK
- KMID: 2274518
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Dec;41(12):1527-1535.
BACKGROUND AND OBJECTIVES: Injection of endotoxin into the middle ear of experimental animals results in otitis media with effusion and transient reversible hearing loss, which occurs in the higher concentration... -
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- The Ototoxicity of Cisplatin is Mediated by NO: A Study using L-NAME and MK-801 in Guinea pigs
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Rhee CK, Oh YH, Jeon SJ, Chung SY, Oh CH
- KMID: 2275942
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Aug;45(8):741-746.
BACKGROUND AND OBJECTIVES: Nitric oxide has been suggested to play an important role in the pathogenesis of cisplatin ototoxicity. L-NAME (NG-Nitroarginine Methyl Ester) is an inhibitor of nitric oxide synthase.... -
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- The Effect of Pretreatment of CoCl2 on the Prevention of Noise-Induced Hearing Loss
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Shin JE, Kang HH, Chung JW
- KMID: 1875399
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2007 Sep;50(9):743-749.
BACKGROUND AND OBJECTIVES: The study was designed to investigate the changes in the expression of hypoxia inducible factor-1alpha (HIF-1alpha) according to time after being exposed to noise trauma and find... -
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- Effect of Melatonin on the Cisplatin Induced Ototoxicity in Rats
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Kim JG, Park SH, Nam SI, Chang EJ, Mun KC, Kim SP
- KMID: 2276043
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Oct;46(10):808-814.
BACKGROUND AND OBJECTIVES: Cisplatin (CP), an antitumor agent widely used in the treatment of head and neck cancers, has side effects such as ototoxicity and nephrotoxicity. These side effects are... -
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- Protective Effect of Hexane and Ethanol Extract of Piper Longum L. on Gentamicin-Induced Hair Cell Loss in Neonatal Cultures
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Yadav MK, Choi J, Song JJ
- KMID: 2278396
- Clin Exp Otorhinolaryngol.
- 2014 Mar;7(1):13-18.
OBJECTIVES: Gentamicin (GM) is a commonly used aminoglycoside antibiotic that generates free oxygen radicals within the inner ear, which can cause vestibulo-cochlear toxicity and permanent damage to the sensory hair... -
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- Outward Rectifying Current in Isolated Deiters' Cells from Guinea Pig Cochlea
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Kim HJ, Ahn JH, Kim WT, Leem CH, Chung JW, Lee KS
- KMID: 1887269
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Jun;45(6):550-556.
BACKGROUND AND OBJECTIVES: The Deiters' cell is one of the supporting cells in the organ of Corti and is known to possibly regulate the signal transduction pathway in the organ... -
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