- Stem Cell Properties of Therapeutic Potential
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Seo GS
- KMID: 1018399
- Korean J Gastroenterol.
- 2011 Sep;58(3):125-132.
- doi: 10.4166/kjg.2011.58.3.125
Stem cell research is a innovative technology that focuses on using undifferentiated cells able to self-renew through the asymmetrical or symmetrical divisions. Three types of stem cells have been studied... -
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- Nuclear receptor regulation of stemness and stem cell differentiation
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Jeong Y, Mangelsdorf DJ
- KMID: 1119318
- Exp Mol Med.
- 2009 Aug;41(8):525-537.
- doi: 10.3858/emm.2009.41.8.091
Stem cells include a diverse number of toti-, pluri-, and multi-potent cells that play important roles in cellular genesis and differentiation, tissue development, and organogenesis. Genetic regulation involving various transcription... -
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- Very small embryonic-like stem-cell optimization of isolation protocols: an update of molecular signatures and a review of current in vivo applications
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Shin DM, Suszynska , Mierzejewska K, Ratajczak , Ratajczak
- KMID: 2154275
- Exp Mol Med.
- 2013 Nov;45(11):e56.
As the theory of stem cell plasticity was first proposed, we have explored an alternative hypothesis for this phenomenon: namely that adult bone marrow (BM) and umbilical cord blood (UCB)... -
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- Human embryonic stem cells and therapeutic cloning
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Hwang WS, Lee BC, Lee CK, Kang SK
- KMID: 1114848
- J Vet Sci.
- 2005 Jun;6(2):87-96.
The remarkable potential of embryonic stem (ES) cells is their ability to develop into many different cell types. ES cells make it possible to treat patients by transplanting specialized healthy... -
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- In vitro neuronal and osteogenic differentiation of mesenchymal stem cells from human umbilical cord blood
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Park KS, Lee YS, Kang KS
- KMID: 1089481
- J Vet Sci.
- 2006 Dec;7(4):343-348.
- doi: 10.4142/jvs.2006.7.4.343
Mesenchymal stem cells (MSCs) have the capabilities for self-renewal and differentiation into cells with the phenotypes of bone, cartilage, neurons and fat cells. These features of MSCs have attracted the... -
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- The New Sysmex XN-2000 Automated Blood Cell Analyzer More Accurately Measures the Absolute Number and the Proportion of Hematopoietic Stem and Progenitor Cells Than XE-2100 When Compared to Flow Cytometric Enumeration of CD34+ Cells
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Park SH, Park CJ, Kim MJ, Han MY, Han SH, Cho YU, Jang S
- KMID: 2363164
- Ann Lab Med.
- 2015 Jan;35(1):146-148.
- doi: 10.3343/alm.2015.35.1.146
No abstract available. -
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- Dynamic changes of gangliosides expression during the differentiation of embryonic and mesenchymal stem cells into neural cells
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Kwak DH, Yu K, Kim SM, Lee DH, Kim SM, Jung JU, Seo JW, Kim N, Lee SK, Jung KY, You H, Kim HA, Choo YK
- KMID: 1115945
- Exp Mol Med.
- 2006 Dec;38(6):668-676.
Stem cells are used for the investigation of developmental processes at both cellular and organism levels and offer tremendous potentials for clinical applications as an unlimited source for transplantation. Gangliosides,... -
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- The Fetal Sheep: A Unique Model System for Assessing the Full Differentiative Potential of Human Stem Cells
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Porada GA, Porada C, Zanjani ED
- KMID: 1726138
- Yonsei Med J.
- 2004 Jun;45(Suppl):S7-S14.
- doi: 10.3349/ymj.2004.45.Suppl.7
The naturally occurring stem cell migratory patterns, the availability of expanding homing and engraftment sites, and the presence of tissue/organ-specific signals in the developing mammalian fetus provide the ideal setting... -
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- Vascular differentiation of multipotent spermatogonial stem cells derived from neonatal mouse testis
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Im JE, Song SH, Kim JY, Kim KL, Baek SH, Lee DR, Suh W
- KMID: 1365907
- Exp Mol Med.
- 2012 Apr;44(4):303-309.
- doi: 10.3858/emm.2012.44.4.034
We previously reported the successful establishment of embryonic stem cell (ESC)-like multipotent spermatogonial stem cells (mSSCs) from neonatal mouse testis. Here, we examined the ability of mSSCs to differentiate into... -
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- Glioma Stem Cell-Targeted Dendritic Cells as a Tumor Vaccine Against Malignant Glioma
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Ji B, Chen Q, Liu B, Wu L, Tian D, Guo Z, Yi W
- KMID: 1776923
- Yonsei Med J.
- 2013 Jan;54(1):92-100.
- doi: 10.3349/ymj.2013.54.1.92
PURPOSE: Cancer stem cells have recently been thought to be closely related to tumor development and reoccurrence. It may be a promising way to cure malignant glioma by using glioma... -
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- Efficient culture system for human embryonic stem cells using autologous human embryonic stem cell-derived feeder cells
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Yoo SJ, Yoon BS, Kim JM, Song JM, Roh SI, You S, Yoon HS
- KMID: 1089449
- Exp Mol Med.
- 2005 Oct;37(5):399-407.
Human embryonic stem cells (hESCs) need feeder cells for their maintenance in an undifferentiated state. In conventional culture systems, mouse embryonic fibroblasts (MEFs) serve as feeder cells to maintain hESCs.... -
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- Hematopoietic Differentiation of Embryoid Bodies Derived from the Human Embryonic Stem Cell Line SNUhES3 in Co-culture with Human Bone Marrow Stromal Cells
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Kim SJ, Kim BS, Ryu SW, Yoo JH, Oh JH, Song CH, Kim SH, Choi DS, Seo JH, Choi CW, Shin SW, Kim YH, Kim JS
- KMID: 2158151
- Yonsei Med J.
- 2005 Oct;46(5):693-699.
- doi: 10.3349/ymj.2005.46.5.693
Human embryonic stem (ES) cells can be induced to differentiate into hematopoietic precursor cells via two methods: the formation of embryoid bodies (EBs) and co-culture with mouse bone marrow (BM)... -
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- Advanced Properties of Urine Derived Stem Cells Compared to Adipose Tissue Derived Stem Cells in Terms of Cell Proliferation, Immune Modulation and Multi Differentiation
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Kang HS, Choi SH, Kim BS, Choi JY, Park GB, Kwon TG, Chun SY
- KMID: 2359960
- J Korean Med Sci.
- 2015 Dec;30(12):1764-1776.
- doi: 10.3346/jkms.2015.30.12.1764
Adipose tissue stem cells (ADSCs) would be an attractive autologous cell source. However, ADSCs require invasive procedures, and has potential complications. Recently, urine stem cells (USCs) have been proposed as... -
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- In situ tissue regeneration through host stem cell recruitment
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Ko IK, Lee SJ, Atala A, Yoo JJ
- KMID: 2154276
- Exp Mol Med.
- 2013 Nov;45(11):e57.
The field of tissue engineering has made steady progress in translating various tissue applications. Although the classical tissue engineering strategy, which involves the use of culture-expanded cells and scaffolds to... -
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- Isolation of neural precursor cells from skeletal muscle tissues and their differentiation into neuron-like cells
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Park JS, Kim S, Han DK, Lee JY, Ghil SH
- KMID: 756071
- Exp Mol Med.
- 2007 Aug;39(4):483-490.
Skeletal muscle contains several precursor cells that generate muscle, bone, cartilage and blood cells. Although there are reports that skeletal muscle-derived cells can trans-differentiate into neural-lineage cells, methods for isolating... -
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- Clinical Application of Marrow Mesenchymal Stem Cells for Hard Tissue Repair
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Ohgushi H, Kitamura S, Kotobuki N, Hirose M, Machida H, Muraki K, Takakura Y
- KMID: 1726148
- Yonsei Med J.
- 2004 Jun;45(Suppl):S61-S67.
- doi: 10.3349/ymj.2004.45.Suppl.61
Human marrow mesenchymal stem cells were cultured in a medium containing glycerophosphate, ascorbic acid, and dexamethasone (Dex) on alumina ceramic discs and on tissue culture polystyrene (TCPS) dishes. Cell proliferation... -
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- Stemness Evaluation of Mesenchymal Stem Cells from Placentas According to Developmental Stage: Comparison to Those from Adult Bone Marrow
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Sung HJ, Hong SC, Yoo JH, Oh JH, Shin HJ, Choi IY, Ahn KH, Kim SH, Park Y, Kim BS
- KMID: 2157843
- J Korean Med Sci.
- 2010 Oct;25(10):1418-1426.
- doi: 10.3346/jkms.2010.25.10.1418
This study was done to evaluate the stemness of human mesenchymal stem cells (hMSCs) derived from placenta according to the development stage and to compare the results to those from... -
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- Cotransplanted Bone Marrow Derived Mesenchymal Stem Cells (MSC) Enhanced Engraftment of Hematopoietic Stem Cells in a MSC-dose Dependent Manner in NOD/SCID Mice
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Kim DH, Yoo KH, Yim YS, Choi J, Lee SH, Jung HL, Sung KW, Yang SE, Oh WI, Yang YS, Kim SH, Choi SY, Koo HH
- KMID: 1713108
- J Korean Med Sci.
- 2006 Dec;21(6):1000-1004.
- doi: 10.3346/jkms.2006.21.6.1000
Transplantation of marrow-derived mesenchymal stem cells (MSCs), expanded by culture in addition to whole bone marrow, has been shown to enhance engraftment of human hematopoietic stem cells (HSCs). Our hypothesis... -
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- Cross-talk between BubR1 expression and the commitment to differentiate in adipose-derived mesenchymal stem cells
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Lee J, Lee CG, Lee KW, Lee CW
- KMID: 1099864
- Exp Mol Med.
- 2009 Dec;41(12):873-879.
- doi: 10.3858/emm.2009.41.12.093
BubR1 mitotic checkpoint kinase monitors attachment of microtubules to kinetochores and links regulation of the chromosome-spindle attachment to mitotic checkpoint signaling. Defects in BubR1-mediated signaling severely perturb checkpoint control and... -
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- Migration of human neural stem cells toward an intracranial glioma
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Jeon JY, An JH, Kim SU, Park HG, Lee MA
- KMID: 1103591
- Exp Mol Med.
- 2008 Feb;40(1):84-91.
- doi: 10.3858/emm.2008.40.1.84
Many in vivo and in vitro studies have demonstrated the targeted migration of neural stem cells (NSC) to infiltrating brain tumors, including malignant glioma, highlighting a potential therapeutic approach. However,... -
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