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Expression Patterns of Cytokeratin and Involucrin in the Epidermis of the Artificial Skin Reconstructed by Cultured Cells

Song IH, Lee CK, Sung EK

  • KMID: 2071845
  • Korean J Phys Anthropol.
  • 1999 Jun;12(1):83-90.
To investigate differentiation and growth process of keratinocytes in organotypic cultured skin, we carried out immunohistochemical studies for cytokeratin (CK) 10, 14, 16, 17 and involucrin in the cultured skin....
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A study on the long-term preservation of artificial skin

Park HC, Lee HS, Park JK

  • KMID: 1939860
  • J Korean Surg Soc.
  • 1993 Nov;45(5):618-632.
No abstract available.
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Reconstruction of Artificial Skin In Vitro

Song IH

  • KMID: 2283099
  • Korean J Phys Anthropol.
  • 1998 Dec;11(2):247-260.
Artificial skin can be employed as a useful model for investigating skin disease and clinical application such as burn. To evaluate this, the skin was reconstructed by culturing keratinocytes in...
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A study on the applicability of polymer(polyglactin)for the artificial dermis

Hong SP, Park JK, Huh SH, Kim HS

  • KMID: 2204157
  • J Korean Soc Plast Reconstr Surg.
  • 1998 Jun;25(4):547-556.
The result of artificial skins made with collagen is poor after grafting over the full thickness wounds due to their rapid degradation by enzymatic cleavage. This study is an in...
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Distribution Patterns of Involucrin in the Stratum Corneum of the Normal and Psoriatic Artificial Skins

Song IH, Sung HK, Kim JY, Sung EK, Lee Y, Park JH, Moon YS, Kim HT, Chang SI

  • KMID: 2030762
  • Korean J Anat.
  • 2004 Apr;37(2):191-198.
Cornified envelope is highly insoluble structure formed beneath the plasma membrane during terminal differentiation of keratinocytes and is stabilized by cross linking of various proteins, including involucrin, loricrin, and cornifin....
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Application of Human Dermal Fibroblast and Keratinocyte on Allogenic Dermis(AlloDerm(R))

Oh JC, Lim YK, Jeong JH

  • KMID: 2120133
  • J Korean Soc Plast Reconstr Surg.
  • 2006 Sep;33(5):601-605.
PURPOSE: Large skin defect by various causes, should be covered by autologous skin graft. But, the donor site of autologous skin graft is limited and leaves permanent donor scar and...
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Treatment of Bone and Tendon-Exposed wounds using-Terudermis

Choi MH, Yi SB, Hwang JW, Yang WS, Lee KK

  • KMID: 2119537
  • J Korean Soc Plast Reconstr Surg.
  • 1999 May;26(3):491-497.
Deep skin and soft tissue defects with exposed bone and tendon is difficult to treat, because skin graft rarely survives and flap surgery is sacrifice of donor site. Since "Stage...
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The Effects of Adipose Tissue-Derived Mesenchymal Stem Cells on the Formation ofEpidermis and Basement Membrane in Artificial Skin Models

Byun HJ, Lee SH, Kim JE, Kim YK, Cho KH

  • KMID: 1484221
  • Korean J Dermatol.
  • 2008 Sep;46(9):1186-1193.
BACKGROUND: There is an increasing need for making a more ideal artificial skin model. OBJECTIVE: To evaluate the effects of adipose tissue-derived mesenchymal stem cells (ATMSC) on the formation of epidermis...
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Evaluation of the Various Artificial Skin Substitutes Implanted onto Nude Mice

Lee WJ, Lee DW, Hur JY, Lee YD, Park BY, Rah DK

  • KMID: 2098570
  • J Korean Soc Plast Reconstr Surg.
  • 2008 Mar;35(2):127-133.
PURPOSE: The purpose of this study is to evaluate the remodeling process of the various skin substitutes in 4th and 6th weeks following the transplantation when transplanted onto nude mice. METHODS:...
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Radioprotective effects of dimethyl sulfoxide in the artificial skin reconstructed with cultured human cells

Ryu YH, Choi KS, Song IH

  • KMID: 1571846
  • Korean J Oral Maxillofac Radiol.
  • 2002 Mar;32(1):11-18.
PURPOSE: To evaluate cultured human artificial skin as an experimental model for studying radiation effects in vitro. MATERIALS AND METHODS: The skin was constructed by culturing keratinocytes over collagen lattice...
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Clinical Application of Artificial Edrmis (terudemis) for Exposed Tendon and Bone Area

Lee HS, Lee CJ, Gil MS, Lee SI

  • KMID: 2204008
  • J Korean Soc Plast Reconstr Surg.
  • 1999 Sep;26(5):991-995.
Local or distant flap surgery has been applied in the soft tissue defect area where bone and tendon are exposed, but there are many pitfalls in these surgeries including limitation...
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Maximal Tension of Human Epidermis Prepared from Suction Blisters

Lee MA, Kang HC

BACKGROUND: Epidermis is directly exposed to various external stimuli and protects internal structures. Most studies about skin tension focused on the dermis, and epidermal tension has not been able to...
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Tissue-engineered human living skin substitutes: development and clinical application

Lee KH

The skin acts as a barrier to exogenous substances, pathogens, and trauma. Skin defects caused by burns, venous ulcer, diabetic ulcer, or acute injury occasionally induce life-threatening situations. Tissue engineering...
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Development of Psoriasis Model in Vitro

Song IH, Sung EK, Kim JY, Lee YC, Lee MS

  • KMID: 1530295
  • Korean J Anat.
  • 1998 Dec;31(6):923-935.
Psoriasis is a disease caused by hyperproliferation of keratinocytes. Pathogenesis of psoriasis is still unclear, but many reports suggest that psoriatic keratinocytes themselves may have some factors of pathogenesis. The...
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Expression of Skin Sulfhydryl Oxidase in Normal Skin , Cultured Skin and Several Abnormally Keratinizing Dermatoses

Kim KH, Eun HC

  • KMID: 2303522
  • Korean J Dermatol.
  • 1996 Dec;34(6):908-918.
BACKGROUND: Skin sulfhydryl oxidase(SSO) is the enzyme catalyzing the covalent crosslinking of the protein molecules via disulfide bond formation, which is probably responsible for the formation of tight and stable...
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The Investigation of the Melanocytes in a Cultured Skin Equivalent Model

Sung EK, Park YM, Sung HK, Kim JY, Lee YC, Park JH, Kim HT, Song IH

  • KMID: 2092718
  • Korean J Anat.
  • 2000 Feb;33(1):89-98.
Melanocytes grown in the pure monolayer culture lack the three-dimentional organization and the cellular interactions that exist in vivo. These can be partially overcome by growing melanocytes together with other...
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An Developmental Study of Artificial Skin Using the Alginate Dermal Substrate: Preliminary Report

Park DH, Shin JI

  • KMID: 2120054
  • J Korean Soc Plast Reconstr Surg.
  • 2006 Jan;33(1):21-30.
Alginate, a polymer of guluronic and mannuronic acid, is used as a scaffolding material in biomedical applications. The research was to produce highly-purified alginate from seaweeds and to evaluate the...
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Attachment and Growth of Cultured Fibroblasts on Chitosan Sponge

Park KC, Lee SJ, Kim S, Han WS, Choi HO, Park KD, Kwon IK

  • KMID: 2203903
  • J Korean Soc Plast Reconstr Surg.
  • 2000 Jul;27(4):367-371.
Closure of large skin wounds with split-thickness skin graft requires extensive harvesting of autologous skin. The limitation of available donor areas has sought various kinds of skin equivalents for coverage of skin...
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The Use of Matriderm and Autologous Skin Graft in the Treatment of Full Thickness Skin Defects

Min JH, Yun IS, Lew DH, Roh TS, Lee WJ

BACKGROUND: For patients with full thickness skin defects, autologous Split-thickness skin grafts (STSG) are generally regarded as the mainstay of treatment. However, skin grafts have some limitations, including undesirable outcomes...
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Scalded Skin of Rat Treated by Using Fibrin Glue Combined with Allogeneic Bone Marrow Mesenchymal Stem Cells

Yang Y, Zhang W, Li Y, Fang G, Zhang K

  • KMID: 2368147
  • Ann Dermatol.
  • 2014 Jun;26(3):289-295.
BACKGROUND: It is difficult to achieve satisfactory results with the traditional treatment of large-area skin defects and deep burns. OBJECTIVE: To test the treatment effect of an active dressing film made...
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