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Nonkaryophilic T Antigen of Simian Virus 40 does not have the Functions of Transcriptional Regulation and Transformation

Kim GS, Kim YH, Kim DH

  • KMID: 1571379
  • J Bacteriol Virol.
  • 2001 Jun;31(2):155-161.
No abstract available.
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Well-Differentiated Papillary Mesothelioma of the Tunica Vaginalis: A Case Study and Review of the Literature

Erdogan S, Acikalin A, Zeren H, Gonlusen G, Zorludemir S, Izol V

  • KMID: 2277384
  • Korean J Pathol.
  • 2014 Jun;48(3):225-228.
Well-differentiated papillary mesothelioma is an uncommon tumor of the testes that usually presents as a hydrocele. Here, we present the case of one patient who did not have a history...
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Detection of SV40 Large T Antigen in Malignant Lymphomas

Kim YA, Chang M, Paik J, Yoon SO, Jeon YK, Kim CW, Kim JE

  • KMID: 2459589
  • Korean J Pathol.
  • 2009 Aug;43(4):312-316.
BACKGROUND: The association of simian virus 40 (SV40) with certain types of human cancers, including malignant lymphomas, has been a topic of interest for some time. Although the virus is...
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No Detection of Simian Virus 40 in Malignant Mesothelioma in Korea

Eom M, Abdul-Ghafar J, Park SM, Han JH, Hong SW, Kwon KY, Ko ES, Kim L, Kim WS, Ha SY, Lee KY, Lee CH, Yoon HK, Choi YD, Chung MJ, Jung SH

  • KMID: 2277456
  • Korean J Pathol.
  • 2013 Apr;47(2):124-129.
BACKGROUND: Simian virus 40 (SV40), a polyomavirus, was discovered as a contaminant of a human polio vaccine in the 1960s. It is known that malignant mesothelioma (MM) is associated with...
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Immortalization of human embryonic fibroblasts by overexpression of c-myc and simian virus 40 large T antigen

Kim HS, Shin JY, Yun JY, Ahn DK, Lee JY

  • KMID: 1457544
  • Exp Mol Med.
  • 2001 Dec;33(4):293-298.
SV40 large T antigen, a viral oncoprotein, is known to immortalize human diploid fibroblast by soaking up cellular RB and p53, but its frequency is extremely low. Additional genetic alteration...
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The effect of telomerase expression on the escape from M2 crisis in virus-transformed human retinal pigment epithelial cells

Park JK, Kim BH, Han YS, Park IK

  • KMID: 1081459
  • Exp Mol Med.
  • 2002 May;34(2):107-113.
Transformation with viral oncogene extends the lifespan of normal cells beyond replicative senescence called M1, but most of them eventually succumb to second crisis called M2 when telomeres become critically...
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The Translocation of Nuclaer Factor Kappa B on Corneal Epithelial Cells after Ultraviolet B Irrradiation

Lee DH, Choi KD, Joo CK

  • KMID: 2125407
  • J Korean Ophthalmol Soc.
  • 2002 Jan;43(1):171-177.
PURPOSE: To seek the role of nuclear factor kappa B (NF-kB) on the corneal epithelial cell death after ultraviolet (UV) irradiation. METHODS: Human corneal epithelial cells transfected by Simian Virus 40...
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The Role of Nuclear Factor Kappa B on Lens Epithelial Cells after Ultraviolet B Irradiation

Lee DH, Kim JK, Oh SH, Kim EK, Joo CK

  • KMID: 1902563
  • J Korean Ophthalmol Soc.
  • 2004 Mar;45(3):500-506.
PURPOSE: This study was performed to determine the role of nuclear factor kappa B (NF-kappa B) on the lens epithelial cell death after ultraviolet (UV) irradiation. METHODS: Simian virus 40...
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Evaluation of Vascular Smooth Muscle Cell Lineages Derived from the Transgenic Mice Expressing Temperature-Sensitive Simian Virus 40 T Antigen Targeted to Smooth Muscle

Huh NE

BACKGROUND AND OBJECTIVES: As a part of efforts to evaluate effectiveness of aorta cell lineages derived from the transgenic mice in which expression of the temperature-sensitive SV40 large T antigen...
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In vitro Induction of Cellular Differentiation of Human Fetal Liver Cell Lines with Sodium Butyrate

Yoon JH, Lee JS, Lee HS, Kim CY

  • KMID: 1531713
  • Korean J Hepatol.
  • 1997 Sep;3(3):193-201.
BACKGROUND/AIMS: Imrnortalized human fetal liver cell lines established by transfecting simian virus 40 T gene wae found to lose differentiated liver cell functions in successive long-term culture. Butyrate, known as a differentiation-promoting agent...
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Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes

Wang C, Hwang YL, Li XM, Kim SJ, Zhu MJ, Lee JH, Jiang RH, Kim CD

BACKGROUND: Sebocytes are the major cells of sebaceous gland. The essential role of sebocytes is the production of sebum, a specific lipid mixture, that covers the body surface and provides...
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Immunohistochemical study of p21 and p53 expression in ameloblastoma

Shin DJ, Myoung H, Hwang KK, Kim MJ

  • KMID: 2137006
  • J Korean Assoc Oral Maxillofac Surg.
  • 2003 Aug;29(4):199-205.
The p53 protein was discovered in 1979 as cellular 53-kD nuclear phosphoprotein bound to the large transforming antigen of SV40 virus. P21WAF1/CIP1, which has been described as the critical downstream...
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