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Squamous cell carcinoma antigen in cervical cancer and beyond

Kim BG

No abstract available.
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The Effects of Antithrombin III on Disseminated Intravascular Coagulation(DIC) in Premature Infants

Park EA

OBJECTIVES: Sepsis and its associated complication of disseminated intravascular coagulation (DIC) are considered to be a major cause of morbidity and mortality in the newborn infants. Antithrombin(AT) is a single...
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Clinicopathological Significance of Maspin Expression in Breast Cancer

Lee MJ, Suh CH, Li ZH

Maspin is a unique serine proteinase inhibitor that has tumor suppressor activity. It has been reported that maspin is expressed in normal human mammary epithelial cells and it is down-regulated...
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The Role of Neutrophil Estrogen Receptor Status on Maspin Synthesis via Nitric Oxide Production in Human Breast Cancer

Ganguly Bhattacharjee K, Bhattacharyya M, Halder UC, Jana P, Sinha AK

PURPOSE: Estrogen, through its binding to nuclear estrogen receptor (ER), has been implicated in the development of human breast cancer. The presence or absence of ER in breast lesions has...
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Osteogenesis Imperfecta Type VI with Severe Bony Deformities Caused by Novel Compound Heterozygous Mutations in SERPINF1

Cho SY, Ki CS, Sohn YB, Kim SJ, Maeng SH, Jin DK

Osteogenesis imperfecta (OI) comprises a heterogeneous group of disorders characterized by bone fragility, frequent fractures, and low bone mass. Dominantly inherited COL1A1 or COL1A2 mutations appear to be causative in...
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Association Analysis of SERPINB5 Polymorphisms with HBV Clearance and HCC Occurrence in a Korean Population

Kim JY, Park TJ, Lee JS, Chun JY, Bae JS, Park BL, Cheong HS, Lee HS, Kim YJ, Shin HD

  • KMID: 2166471
  • Genomics Inform.
  • 2010 Mar;8(1):1-8.
Serpin peptidase inhibitor, Clade B (ovalbumin), Member 5 (SERPINB5), also known as maspin, is a potent tumor suppressor gene. It has correlations with many tumor cells, from pancreas cancer to...
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Utility of serum squamous cell carcinoma antigen levels at the time of recurrent cervical cancer diagnosis in determining the optimal treatment choice

Shimura K, Mabuchi S, Yokoi T, Sasano T, Sawada K, Hamasaki T, Kimura T

OBJECTIVE: To investigate the utility of serum squamous cell carcinoma antigen (SCC-Ag) levels upon the diagnosis of recurrent cervical cancer for decision making in patient management. METHODS: Clinical records from 167...
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Maspin Suppresses Survival of Lung Cancer Cells through Modulation of Akt Pathway

Nam E, Park C

  • KMID: 2165976
  • Cancer Res Treat.
  • 2010 Mar;42(1):42-47.
PURPOSE: Maspin is a tumor suppressor protein that has been reported to stimulate the cell death of cancer and inhibit the metastasis of cancer. The present study aimed to explore...
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A study for diagnosis of squamous cell carcinoma arising from mature cystic teratoma

Ji HY, Kim TJ, Kim MJ, Lee EJ, Lee YY, Kim CJ, Choi CH, Lee JW, Kim BG, Bae DS

  • KMID: 2273815
  • Korean J Obstet Gynecol.
  • 2009 Dec;52(12):1258-1264.
OBJECTIVE: To evaluate factors for diagnosis of squamous cell carcinoma arising from ovarian mature cystic teratoma and whether squamous cell carcinoma (SCC) antigen, CA125, CA19-9 and CEA is useful for...
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Prognostic value of pre-treatment SCC-Ag level in patients with cervical cancer

An JJ, Lee YY, Park JY, Choi CH, Kim TJ, Lee JW, Kim BG, Bae DS

OBJECTIVE: The purpose of this study is to investigate the prognostic role of pre-treatment squamous cell carcinoma-related antigen (SCC-Ag) level in patients with squamous cell carcinoma of the uterine cervix. METHODS:...
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Posttreatment cut-off levels of squamous cell carcinoma antigen as a prognostic factor in patients with locally advanced cervical cancer treated with radiotherapy

Kawaguchi , Furukawa N, Kobayashi , Asakawa I

OBJECTIVE: The aim of the present study was to assess prognostic factors for patients with locally advanced cervical cancer treated with radiotherapy as the primary treatment and to assess the...
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The role of squamous cell carcinoma antigen as a prognostic and predictive factor in carcinoma of uterine cervix

Jeong BK, Choi DH, Huh SJ, Park W, Bae DS, Kim BG

PURPOSE: Although the role of squamous cell carcinoma antigen (SCC-Ag) as a predictive and prognostic factor for uterine cervical cancer has been identified in previous studies, 1) the effective patient...
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Prognostic Value of Different Patterns of Squamous Cell Carcinoma Antigen Level for the Recurrent Cervical Cancer

Jeong BK, Huh SJ, Choi DH, Park W, Bae DS, Kim BG

  • KMID: 2167607
  • Cancer Res Treat.
  • 2013 Mar;45(1):48-54.
PURPOSE: In some unusual cases, in patients with cervical cancer, an elevation of squamous cell carcinoma antigen (SCC-Ag) was not observed at diagnosis but was observed on recurrence, or vice...
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Maspin Expression and Its Clinical Significance in Non-Small Cell Lung Cancer

Yoon SH, Kim WJ, Shin KH, Kim MH, Cho WH, Kim KU, Park HK, Jeon DS, Kim YS, Lee CH, Lee MK, Park SK

BACKGROUND: Maspin (mammary serine protease inhibitor) is a member of the serpin superfamily. A few studies have examined the role of maspin in tumor suppression of non-small cell lung cancer...
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Clinical Usefulness of 18F-FDG PET/CT in the Detection of Early Recurrence in Treated Cervical Cancer Patients with Unexplained Elevation of Serum Tumor Markers

Chong A, Ha JM, Jeong SY, Song HC, Min JJ, Bom HS, Choi HS

We investigated the diagnostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) for restaging of treated uterine cervix squamous cell cancer with tumor maker elevation that was not explained by...
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Down-regulated serum microRNA-101 is associated with aggressive progression and poor prognosis of cervical cancer

Jiang W, Pan JJ, Deng YH, Liang MR, Yao LH

OBJECTIVE: MicroRNAs (miRNAs) play a vital role in pathogenesis and progression of many cancers, including cervical cancer. However, importance of serum level of miR-101 in cervical cancer has rarely been...
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Pretreatment risk factors for parametrial involvement in FIGO stage IB1 cervical cancer

Yamazaki H, Todo Y, Okamoto K, Yamashiro , Kato H

OBJECTIVE: All patients with stage IB1 cervical cancer do not need to undergo parametrectomy. Some low-risk criteria for parametrial involvement (PI) have been proposed based on pathological findings. The aim...
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Salvage radiotherapy for lymph node recurrence after radical surgery in cervical cancer

Jeon W, Koh HK, Kim HJ, Wu HG, Kim JH, Chung HH

OBJECTIVE: This study was to evaluate the treatment outcomes and prognostic factors of patients treated with salvage radiotherapy for the treatment of isolated lymph node recurrence of cervical cancer. METHODS: Between...
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Clinical significance of tumor volume and lymph node involvement assessed by MRI in stage IIB cervical cancer patients treated with concurrent chemoradiation therapy

Lee DW, Kim YT, Kim JH, Kim S, Kim SW, Nam EJ, Kim JW

OBJECTIVE: The purpose of this study was to evaluate the prognostic significance of tumor volume assessed by pretreatment MRI in stage IIB cervical cancer patients with concurrent chemoradiation therapy. METHODS:...
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Prognostic Significance of Maspin in Pancreatic Ductal Adenocarcinoma

Lim YJ, Lee JK, Jang WY, Song SY, Lee KT, Paik SW, Rhee JC

  • KMID: 759679
  • Korean J Intern Med.
  • 2004 Mar;19(1):15-18.
BACKGROUND: Maspin is a serpin family of protease inhibitors. Althouth maspin has been considered a tumor suppressor that inhibits the motility, invasion, and metastasis of breast and prostatic cancer cells,...
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