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Effect of serine protease inhibitor on follicular development in the rat ovary

Yoon BK, Lee JY

  • KMID: 1698600
  • Korean J Fertil Steril.
  • 1993 Jun;20(1):19-29.
No abstract available.
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Serine Proteases of Parasitic Helminths

Yang Y, Wen YJ, Cai YN, Vallee I, Boireau P, Liu MY, Cheng SP

Serine proteases form one of the most important families of enzymes and perform significant functions in a broad range of biological processes, such as intra- and extracellular protein metabolism, digestion,...
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Activation of Eosinophils with Airborne Fungi

Shin SH, Kim JK, Kita H

  • KMID: 2276174
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Jun;47(6):549-553.
BACKGROUND AND OBJECTIVES: Allergic fungal sinusitis is characterized by allergic mucin which includes eosinophils and fungal hyphae. But we don't know why eosinophils are accumulated at the nasal secretion and...
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Partial Purification and Characterization of 41 kDa Serine Proteinase from Culture Filtrate of Trichophyton tonsurans

Yoo JI, Lee YS, Choi YH, Joo HY, Kim BS, Suh SB

  • KMID: 2146911
  • J Korean Soc Microbiol.
  • 1999 Jun;34(3):303-310.
Dermatophytes infect the human hair, skin, nail and cause the dermatophytosis. The extracellular and intracellular proteinases of the dermatophytes commonly occur in the genus Trichophyton like T. rubrum, T. mentagrophytes,...
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Netherton Syndrome in Two Sisters

Kim SY, Kim MH, Choi HY, Myung KB

  • KMID: 2302678
  • Korean J Dermatol.
  • 2005 Mar;43(3):379-382.
Netherton Syndrome is a rare autosomal recessive inherited disorder, characterized by triad of congenital ichthyosiform dermatosis, trichorrhexis invaginata and atopy diathesis. It has been found to be due to mutations...
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Phorbol Ester Induced - Apoptosis Mediated by Activating Serine Protease ( s ) and Caspase - 3 / CPP32 in SNU - 16 Human Gastric Cancer Cell Line

Park IC, Park MJ, Choe TB, Jang JJ, Hong SI, Lee SH

  • KMID: 2175097
  • J Korean Cancer Assoc.
  • 2000 Apr;32(2):270-278.
PURPOSE: Protein kinase C (PKC) is a family of phospholipid dependent serine/threonine protein kinases that have important role in differentiation, development and tumor promotion. PKC also has been reported to be implicated...
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Cloning of a Family of Serine Protease Genes Expressed in German Cockroach(Blattella germanica) and Possibility as Allergens

Lee WY, Kim HB, Park JR, Park SH, Park KW, Ock MS, Yu TH

  • KMID: 2276895
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Jun;51(6):528-534.
BACKGROUND AND OBJECTIVES: The serine protease allergens have been known as one of the most important inhalent allergens of insects as well as house dust mites. There is no known...
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Protease from Airborn Fungi Induce Activation of Nasal Epithelial Cells

Shin SH, Park GU, Jeon CH

  • KMID: 2037116
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Feb;48(2):189-194.
BACKGROUND AND OBJECTIVES: The nasal epithelium is the first barrier encountered by airborne allergens and an active participant in airway inflammation. Fungi have been increasingly recognized as important pathogens in...
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iRhoms; Its Functions and Essential Roles

Lee MY, Nam KH, Choi KC

In Drosophila, rhomboid proteases are active cardinal regulators of epidermal growth factor receptor (EGFR) signaling pathway. iRhom1 and iRhom2, which are inactive homologs of rhomboid intramembrane serine proteases, are lacking...
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The Role of Genetic Mutation in the Pathogenesis of Pancreatitis

Paik WH, Jang DK, Lee JK

10–30% of patients with pancreatitis can be categorized as idiopathic pancreatitis, and some of them may be due to genetic alterations. Since hereditary pancreatitis develops from pediatric patients with symptoms...
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Protease-activated Receptor 2 is Associated with Activation of Human Macrophage Cell Line THP-1

Kang CS, Tae J, Lee YM, Kim BS, Moon WS, Kim DK

BACKGROUND: Protease-activated receptor 2 (PAR2) belongs to a family of G protein- coupled receptors activated by proteolytic cleavage. Trypsin-like serine proteases interact with PAR2 expressed by a variety of tissues...
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Therapeutic Implications of a Barrier-based Pathogenesis of Atopic Dermatitis

Elias PM

In this review, I first provide relevant background information about normal epidermal barrier structure and function. I then update recent information about how inherited defects in either filaggrin and/or in...
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Intraoperative Anaphylactoid Reaction Due to Aprotinin during Pediatric Open Heart Surgery

Sim JY, Park JY, Kweon EH, Choi IC

Aprotinin is a serine protease inhibitor that improves the hemostatic function and modulates the anti-inflammatory responses. Recently, aprotinin has been widely used in various surgical procedures including open heart...
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The Effects of Aprotinin of Experimental Corneal Burn in Rabbits

Kim JC, Moon YS, Lee HK, Shyn KH

  • KMID: 2147847
  • J Korean Ophthalmol Soc.
  • 1992 Nov;33(11):1043-1048.
Recently, many works to treat chronic corneal ulcer have been progressed. It has been reported that the Aprotinin, one of them, is serine protease inhibitor and is useful to treat...
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Two Cases of Acute Renal Failure Associated with Aprotinin

Yun YS, Kwon SH, Park EK, Jeon JS, Noh HJ, Han DC, Jin SY

  • KMID: 2253282
  • Korean J Nephrol.
  • 2008 May;27(3):383-388.
Aprotinin is a nonspecific serine protease inhibitor and antifibrinolytic agent. It has been used to control bleeding and reduce the amounts of transfusion during the perioperative period. There are few...
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Proteolytic Regulation of Retinoblastoma Family Protein p107 by Ubiquitin - proteasome Pathway

Jang JS, Park BK, Hwang SG

  • KMID: 2175114
  • J Korean Cancer Assoc.
  • 2000 Apr;32(2):417-421.
PURPOSE: Proteolysis is an important way to regulate cell cycle regulatory proteins. Ubiquitin- proteasome pathway regards as highly selective proteolytic machinary mostly in physiological state. We investigated the role of ubiquitin-proteasome pathway...
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Acute Renal Failure after Operation Associated with Aprotinin: Report of 3 cases

Kim SC, Eom HS, Ok SY, Kim SI

Aprotinin is a serine protease inhibitor and a powerful antifibrinolytic agent, derived from the inhibition of plasmin and kallikrein. Therefore, it is widely used in cardiopulmonary bypass surgery or major...
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The Role of Proteinase in Acanthamoeba keratitis and the Effect of Amniotic Membrane as a Proteinase Inhibitor

Song CH, Song CY, Kim JC

  • KMID: 2205383
  • J Korean Ophthalmol Soc.
  • 1998 Nov;39(11):2527-2541.
This study was performed to investigate the biochemical properties of Acanthamoeba proteinase, its role in the pathogenesis of Acanthamoeba keratitis and the therapeutic effect of the homogenate of amniotic membrane...
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Clinical Significance of Expression of Plasminogen Activatiors in Aural Cholesteatoma

Kim HJ, Kim JH, Lim HJ

  • KMID: 2074346
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Feb;42(2):152-158.
BACKGROUND AND OBJECTIVES: Bone destruction is characteristic of aural cholesteatoma. Plasminogen activator (PA), one of serine proteases, acts as the specific trigger in a proteolytic cascade, which may play a...
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Protease and Protease-Activated Receptor-2 Signaling in the Pathogenesis of Atopic Dermatitis

Lee SE, Jeong SK, Lee SH

Proteases in the skin are essential to epidermal permeability barrier homeostasis. In addition to their direct proteolytic effects, certain proteases signal to cells by activating protease-activated receptors (PARs), the G-protein-coupled...
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