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Distribution of the Glycosaminoglycans in the Bruch`s Membrane and Sensory Retina : Histochemical Electromic roscopic Findings with Ruthenium Red

Lee WK, Ko MK, Kim DS

  • KMID: 2124304
  • J Korean Ophthalmol Soc.
  • 1999 Jul;40(7):1877-1883.
The distribution of glycosaminoglycans in Bruch`s membrane and sensory retina of human eye was evaluated with histochemical electron microscope using 0.05%ruthenium red (RR). Seven donated or enucleated eyeballs without chorioretinal...
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Histochemical Electron Microscopy of Conjunctival Surface in Dry Eye Syndrome

Park IW, Kim DS, Ko MK

  • KMID: 1949237
  • J Korean Ophthalmol Soc.
  • 1989 Aug;30(4):483-488.
This study was performed to evaluate the histochemical changes of the conjunctival epithelial cell in eyes with dry eye syndrome. The authors selected 10 eyes clinically diagnosed as dry eye...
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Histochemical Electron Microscopic Findings of the Distribution of the Glycosaminoglycans of Cultured Sensory Retina

Kim JS, Kwon JW, Ko MK

  • KMID: 2125410
  • J Korean Ophthalmol Soc.
  • 2002 Jan;43(1):197-203.
PURPOSE: This study was performed to investigate the distribution of glycosaminiglycans by the activated retinal neuronal cell on the cultured retinal tissue. METHODS: The retinal tissue was obtained from the donor...
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Histochemical Electron Microscopic Findings of Traumatic Cataract in Rabbits by Ruthenium Red

Yo SI, Kim DS, Ko MK

  • KMID: 2124623
  • J Korean Ophthalmol Soc.
  • 2000 Nov;41(11):2437-2442.
Glycosaminoglycans (GAGs)are essential components of the extracellular matrix of various tissues.They have been known to regulate cellular and extracellular environments for cell survival and differentiation in various physiologic and pathologic...
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N-acetyl-L-cysteine and cysteine increase intracellular calcium concentration in human neutrophils

Hasan MA, Ahn WG, Song DK

N-acetyl-L-cysteine (NAC) and cysteine have been implicated in a number of human neutrophils' functional responses. However, though Ca²⁺ signaling is one of the key signalings contributing to the functional responses...
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The Ultrastructural Changes of Stratum Corneum Lipids after Application of Oleic Acid in Propylene Glycol

Jiang SJ, Kim YK, Lee SH

BACKGROUND: The stratum corneum presents a significant barrier to transdermal drug delivery. Approaches to improve percutaneous absorption of drugs have included iontophoresis and skin penetration enhancers. Oleic acid has been...
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Ca(2+)-induced Ca2+ Release from Internal Stores in INS-1 Rat Insulinoma Cells

Choi KJ, Cho DS, Kim JY, Kim BJ, Lee KM, Kim SH, Kim DK, Kim SH, Park HS

  • KMID: 2389109
  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):53-59.
The secretion of insulin from pancreatic beta-cells is triggered by the influx of Ca2+ through voltage-dependent Ca2+ channels. The resulting elevation of intracellular calcium ([Ca2+]i) triggers additional Ca2+ release from...
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When morphogenetic proteins encounter special extracellular matrix and cell-cell connections at the interface of the renal stem/progenitor cell niche

Minuth WW, Denk L

Reciprocal exchange of morphogenetic proteins between epithelial and mesenchymal cells in a stem/progenitor cell niche results in formation of a nephron. To maintain diffusion of morphogenetic proteins, it is assumed...
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Barrier Rcovery after Topically Applied Desoxymethasone Ontment, Vaseline and Hydrobase on Benzalkonium Chloride-irritated Hairless Mice Skin

Ahn SK, Choi EH, Shaojun J, Hwang SM, Lee SH

  • KMID: 2303423
  • Korean J Dermatol.
  • 1998 Oct;36(5):820-826.
BACKGROUND: Topical irritants disrupt the cutaneous permeability barrier through the removal of stratum comeum lipids. This perturbation of barrier integrity stimulates a variety of homeostatic repair responses that ultimately result...
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(3H)Ryanodine binding sites of SR vesicles of the chicken pectoral muscle

Yun HY, Jeon JR, Hong JH, Hur GM, Lee JH, Seok JH

  • KMID: 2071509
  • Korean J Physiol Pharmacol.
  • 1997 Aug;1(4):377-384.
To investigate the properties of ryanodine binding sites of the bird skeletal SR vesicles, SDS PAGE, purification of RyR, and (3H)ryanodine binding study were carried out in the SR vesicles prepared from...
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Ruthenium-106 Brachytherapy with or without Additional Local Therapy Shows Favorable Outcome for Variable-Sized Choroidal Melanomas in Korean Patients

Cho Y, Chang JS, Yoon JS, Lee SC, Kim YB, Kim JH, Keum KC

PURPOSE: The purpose of this study was to report clinical outcomes of ruthenium-106 (106Ru) brachytherapy with or without additional local therapy for choroidal melanomas in Korean patients. MATERIALS AND METHODS: A...
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Differences in the Recovery Rate after Perturbation of Epidermal Barrier by Means of Acetone Treatment and Tape-Stripping Technique

Chung HS, Lee SH

BACKGROUND: The epidermal permeability barrier necessary for terrestrial life resides in the intercellular spaces of the stratum corneum and is composed of lipids. OBJECTIVE: Since strrtum corneum lipid may be important...
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The Iontophoresis Effect on Recovery After Acute Epidemal Barrier Disruption

Lee SH, Jiang S, Park TH, Yoo CB, Choi EH, Ahn SK

  • KMID: 2303549
  • Korean J Dermatol.
  • 1996 Jun;34(3):375-380.
BACKGROUND: The stratum corneum(SC) has a permeability barrier function which regulates percutaneous absorption by the inhibition of transepidermal water loss(TEWL). Acute mechanical or chemical disruption of the SC induces the...
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Evaluation of Elecsys 2010 Electrochemiluminescent Immunoassay System

Lee JE, Cho HS, Mun JY, Lee CH, Kim KD

  • KMID: 2146204
  • Korean J Clin Pathol.
  • 1997 Dec;17(6):1029-1037.
BACKGROUND: Elecsys 2010 immunoassay system is based on the electrochemiluminescence immunoassay using a ruthenium (II) tris (bipyridyl) label. Since it was the first time to use the system in our...
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The Effect of DA-5018, A Synthetic Capsaicin Derivative,on Voltage-Dependent Calcium Currents in TrigeminalGanglion Neurons of Neonatal Rats

Kim JS

  • KMID: 1883692
  • Chonnam Med J.
  • 2007 Dec;43(3):158-167.
Capsaicin is known to produce initial excitation followed by desensitization to various stimuli on the sensory neurons. The aim of this study was to investigate the electrophysiological characteristics of voltage-dependent...
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The Effect of Bentonite and Glycolic Acid on the Stratum corneum

Kim S, Hwang SM, Choi EH, Ahn SK, Lee SH

BACKGROUND: Bentonite clay, which is a major component of mud pack, has been used for various purposes in cosmetics. Glycolic acid is known to be effective in the treatment of...
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Effects of NaOCl on the Intracellular Calcium Concentration in Rat Dorsal Root Ganglion Neurons

Lee HI, Chun SW

  • KMID: 1457186
  • Int J Oral Biol.
  • 2010 Sep;35(3):129-135.
Recent studies have implicated reactive oxygen species (ROS) as determinants of the pathological pain caused by the activation of peripheral neurons. It has not been elucidated, however, how ROS activate...
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Clinical use of a ceramide-based moisturizer for treating dogs with atopic dermatitis

Jung JY, Nam EH, Park SH, Han SH, Hwang CY

In humans, skin barrier dysfunction is thought to be responsible for enhanced penetration of allergens. Similar to conditions seen in humans, canine atopic dermatitis (CAD) is characterized by derangement of...
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Different uptake of gentamicin through TRPV1 and TRPV4 channels determines cochlear hair cell vulnerability

Lee JH, Park C, Kim SJ, Kim HJ, Oh GS, Shen A, So HS, Park R

  • KMID: 2154231
  • Exp Mol Med.
  • 2013 Mar;45(3):e12.
Hair cells at the base of the cochlea appear to be more susceptible to damage by the aminoglycoside gentamicin than those at the apex. However, the mechanism of base-to-apex gradient...
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Mitochondrial calcium uniporter inhibition attenuates mouse bone marrow-derived mast cell degranulation induced by beta-1,3-glucan

Cuong DV, Kim HK, Marquez J, Kim N, Ko KS, Rhee BD, Han J

Mast cells are primary mediators of allergic inflammation. Beta-1,3-glucan (BG) protects against infection and shock by activating immune cells. Activation of the BG receptor induces an increase in intracellular Ca2+,...
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