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The Effect of Rivastigmine Transdermal Patch on Sleep Apnea in Patients with Probable Alzheimer's Disease

Kim H, Han HJ

BACKGROUND AND PURPOSE: This study was designed to evaluate the effect on sleep of rivastigmine transdermal patch in patients with probable Alzheimer's disease (AD). METHODS: Patients with probable AD underwent a...
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Evaluation of Acute and Chronic Effects of D-Galactose on Memory and Learning in Wistar Rats

Chogtu B, Arivazhahan A, Kunder SK, Tilak A, Sori R, Tripathy A

OBJECTIVE: D-galactose has been commonly used in rodent models to induce accelerated effects of aging, including those on learning, memory, and muscular tone and coordination. This is normally seen on...
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An Analysis on Prescribing Patterns of Alzheimer's Dementia Treatment and Choline Alfoscerate using HIRA Claims Data

Hwang SG, Park H

BACKGROUND: Alzheimer's dementia is the most common dementia. However, recently, choline alfoscerate is prescribed for treating Alzheimer's dementia, although it is not a treatment for this disease. PURPOSE: To analyze the...
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Factors Influencing Skin Tolerability to the Rivastigmine Patch in Patients with Alzheimer's Disease

Na HR, Park MH, Kim S, Yang DW, Choi SH, Yang HD, Yang Y, Han HJ, Lee JS, Yoon YC, Koh SH, Kim JE, Ku BD, Kim HJ, Park KW, Kim EJ, Yoon B, Park KJ

BACKGROUND AND PURPOSE: The one-day rivastigmine patch is reportedly well tolerated and has minimal side effects. However, Asian patients show more side effects than those in Western countries. We evaluated...
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Pharmacological Treatment Strategies for Alzheimer's Disease

Yang DW

Alzheimer's disease(AD) is one of the most common causes of mental deterioration in elderly individuals, accounting for around 45~60% of the overall cases of dementia over 65 years of age....
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Recent Advances in Diagnosis and Treatment of Alzheimer's Disease

Lee JJ, Lee SB

Alzheimer's disease (AD) is a neurodegenerative disorder in which neuronal loss causes cognitive decline and other neuropsychiatric problems. It can be diagnosed based on history, examination, and appropriate objective assessments,...
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Pharmacological Treatment in Alcohol-induced Cognitive Disorder

Kim DJ, Joe KH

  • KMID: 2340903
  • J Korean Med Assoc.
  • 2008 Jan;51(1):84-89.
Alcohol-induced cognitive disorder is a very severe problem in problem alcohol drinker and alcohol itself seems to be one of the main causalities in the development of senile dementia. However,...
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Pharmacotherapy for dementia

Youn H, Jeong HG

Dementia is a clinical syndrome characterized by a cluster of symptoms and signs that manifest as difficulties in cognitive functions such as memory, psychological and psychiatric changes, and impairments in...
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Efficacy and Safety of Switching from Oral Cholinesterase Inhibitors to the Rivastigmine Transdermal Patch in Patients with Probable Alzheimer's Disease

Han HJ, Lee JJ, Park SA, Park HY, Kim JE, Shim YS, Shim DS, Kim EJ, Yoon SJ, Choi SH

BACKGROUND AND PURPOSE: The goal of this study was to estimate the efficacy and safety of the rivastigmine transdermal patch in patients with probable Alzheimer's disease (AD) who cannot tolerate...
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Pharmacological Treatment for Delirium in Cancer Patients

Lee PJ, Hahm BJ

  • KMID: 2341610
  • J Korean Neuropsychiatr Assoc.
  • 2010 Jan;49(1):20-25.
OBJECTIVES: Despite the fact that delirium is a frequent neuropsychiatric disorder in cancer patients, there are, in Korea, no guidelines for the pharmacological treatment of such delirium. This systematic review...
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Nonpharmacological Interventions for Alzheimer's Disease

Lee SB, Kim KW

Although acetylcholinesterase inhibitors (e.g., tacrine, donepezil, rivastigmine, and galantamine) and NMDA receptor antagonists (e.g., memantin) have demonstrated efficacy in the temporal symptomatic control of cognitive decline and daily function in...
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Visual Hallucinations and Amyloid Deposition in Parkinson's Disease Dementia: A Case Report

Um YH, Kim TW, Jeong JH, Seo HJ, Han JH, Hong SC, Jung WS, Choi WH, Lee CU, Lim HK

Parkinson's disease dementia (PDD) is notorious for its debilitating clinical course and high mortality rates. Consequently, various attempts to investigate predictors of cognitive decline in Parkinson's disease (PD) have been...
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Alcohol and Cognitive Disorder

Joe KH, Chun YM, Chai SH, Kim DJ

  • KMID: 2287404
  • Korean J Psychopharmacol.
  • 2009 Jan;20(1):5-14.
Despite epidemiological studies reporting no negative effects of mild to moderate alcohol drinking on cognitive functioning, a recent well-controlled study showed that chronic mild drinking diminished the volume of the...
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Regional Cerebral Blood Flow Changes in Alzheimer's Disease Patients Treated with Cholinesterase Inhibitors: A Preliminary Study using 99mTC-ECD SPECT

Park MY, Cho I

  • KMID: 2195071
  • J Korean Neurol Assoc.
  • 2003 Jun;21(3):255-260.
BACKGROUND: This study aimed to evaluate regional cerebral blood flow (rCBF) changes using 99mTC-ECD SPECT (Ethylene Cysteine Diethylester Single Photon Emission Computed Tomography) and contemporary clinical responses such as cognitive...
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