- Gastric Cancer and DNA Mismatch Repair
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Kim JJ, Park DI
- KMID: 1598593
- Korean J Gastroenterol.
- 2001 Apr;37(4):233-239.
Cancer developes when mutations accumulate in key growth-regulating genes. The two classes of genes implicated in this malignant transformation are designated oncogenes and tumor-suppressor genes. Recently, a new class of... -
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- The application of TD (Touch-Down) PCR in Diagnosis of leprosy and Detection of MDT-resistant M. leprae
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Kim SK, Lee SB, Kang TJ, Chae GT
- KMID: 1609921
- Korean Lepr Bull.
- 2001 Dec;34(2):13-21.
There are several methods for diagnosis of leprosy, including AFB stain, the measurement of PGL-1 (phenolic glycolipid - 1) antigen titer, and DNA-PCR. In this study, we have used the... -
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- Examination of Geographical, Clinical and Intrahost Variations in the 3' Repeat Region of CagA Gene in Helicobacter pylori
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Park SY, Lee YD, Kim SK
- KMID: 1713833
- J Korean Med Sci.
- 2010 Jan;25(1):61-66.
- doi: 10.3346/jkms.2010.25.1.61
The size variation of the cytoxin-associated protein (cagA), which is dependent on the 3' repeat region (3'RR) of the cagA gene, is known to play a crucial role in the... -
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- Isolation of polymorphic loci from the human genome using multi-locus probe pV47-2
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Nam YS, Lee HR, Han GR, Hwang JJ
- KMID: 1928224
- Korean J Leg Med.
- 1997 Oct;21(2):21-37.
Two polymorphic loci, so- called FS106 and FS185, have been isolated from the human genome, using a multilocus probe pV47-2, which is extensively used in Korea for forensic investigation such... -
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- RepWeb: A Web-Based Search Tool for Repeat-Related Literatures
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Woo T, Kim Y, Kwon J, Seo J
- KMID: 2166261
- Genomics Inform.
- 2007 Jun;5(2):88-91.
Repetitive sequences such as SINE, LINE, and LTR elements form a major part of eukaryotic genomes. A literature search tool that summarizes the information contained within repeat elements would provide... -
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- Genomic Differentiation Among Oyster Mushroom Cultivars Released in Korea by URP-PCR Fingerprinting
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Kang HW, Park DS, Park YJ, You CH, Lee BM, Eun MY, Go SJ
- KMID: 1993707
- Mycobiology.
- 2001 Jun;29(2):85-89.
URP primers of 20 mer derived from repetitive sequence of rice were used to assess genetic variation of oyster mushroom consisting of 10 cultivars of Pleurotus ostreatus, two cultivars of... -
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- Study on Causes of Respiratory Disease to the Middle East Respiratory Syndrome-negative Subjects
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Hwang SJ, Park DJ, Koo HS, Yun HC, Gu PT, Lee MO, Jin SH
- KMID: 2392964
- J Bacteriol Virol.
- 2017 Sep;47(3):156-164.
- doi: 10.4167/jbv.2017.47.3.156
Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe cases of human respiratory disease. The current outbreak of infection with this virus in South Korea, which began on May 20, 2015,... -
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- Characteristics of Molecular Strain Typing of Mycobacterium tuberculosis Isolated from Korea
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Jang MH, Choi GE, Chang CL, Kim YD
- KMID: 2089813
- Korean J Clin Microbiol.
- 2011 Jun;14(2):41-47.
- doi: 10.5145/KJCM.2011.14.2.41
Molecular strain typing of Mycobacterium tuberculosis is important for the detection of outbreaks of tuberculosis and laboratory cross contamination, as well as the differentiation between re-infection and reactivation of tuberculosis.... -
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- Molecular cloning and characterization of an antigenic protein with a repeating region from Clonorchis sinensis
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Kim TY, Kang SY, Ahn IY, Cho SY, Hong SJ
- KMID: 1720334
- Korean J Parasitol.
- 2001 Mar;39(1):57-66.
- doi: 10.3347/kjp.2001.39.1.57
In the course of immunoscreening of Clonorchis sinensis cDNA library, a cDNA CsRP12 containing a tandem repeat was isolated. The cDNA CsRP12 encodes two putative peptides of open reading... -
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- Molecular Genetic Screening for the SRY(Sex Determining Region of the Y chromosme) Gene in Turner Syndrome Patients
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Shim JY, Yoo HW
- KMID: 1747716
- J Korean Pediatr Soc.
- 1996 Jul;39(7):915-923.
PURPOSE: Turner syndrome is among the most common cytogenetic abnormalities associated with X chromosome. In only 40-60% of Turner syndrome, 45,X monosomy is found and the high prenatal mortality of... -
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- Comparative binding of antitumor drugs to DNA containing the telomere repeat sequence
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Suh D, Oh YK, Ahn BC, Hur MW, Kim HJ, Lee MH, Joo HS, Auh CK
- KMID: 755203
- Exp Mol Med.
- 2002 Nov;34(5):326-331.
Telomeres are the ends of the linear chromosomes of eukaryotes and consist of tandem GT-rich repeats in telomere sequence i.e. 500-3000 repeats of 5'-TTAGGG-3' in human somatic cells, which are... -
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- Comparison of an Automated Repetitive Sequence-based PCR Microbial Typing System with IS6110-Restriction Fragment Length Polymorphism for Epidemiologic Investigation of Clinical Mycobacterium tuberculosis Isolates in Korea
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Jang MH, Choi GE, Shin BM, Lee SH, Kim SR, Chang CL, Kim JM
- KMID: 1781693
- Korean J Lab Med.
- 2011 Oct;31(4):282-284.
- doi: 10.3343/kjlm.2011.31.4.282
Tuberculosis remains a severe public health problem worldwide. Presently, genotyping is used for conducting epidemiologic and clinical studies on tuberculosis cases. We evaluated the efficacy of the repetitive sequence-based PCR... -
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- Prevalence of Trichomoniasis by PCR in Women Attending Health Screening in Korea
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Kim SR, Kim JH, Gu NY, Kim YS, Hong YC, Ryu JS
- KMID: 2164016
- Korean J Parasitol.
- 2016 Apr;54(2):187-190.
- doi: 10.3347/kjp.2016.54.2.187
Trichomoniasis is the most common curable sexually-transmitted infection (STI) worldwide. There are few reports on the prevalence of Trichomonas vaginalis in Korea. The purpose of this study was to examine... -
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- Genetic Polymorphism of Jeju Horses by Microsatellite DNA Markers in Korea
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Lee JE, Shin JH, Yun YM, Lee KK, Lee H, Kweon OK, Yun YS, Suh JG, Shin NS, Seong JK
- KMID: 2312069
- Lab Anim Res.
- 2010 Jun;26(2):219-221.
We determined the genetic diversity and distance between Jeju and Thoroughbred horses by genotyping for 20 microsatellite loci consisting of (TG)n repetitive sequence. The expected heterozygosity ranged from 0.1 to... -
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- PCR-RFLP patterns of four isolates of Trichinella for rDNA ITS1 region
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Kwon HS, Chung MS, Joo KH
- KMID: 1720332
- Korean J Parasitol.
- 2001 Mar;39(1):43-48.
- doi: 10.3347/kjp.2001.39.1.43
We have studied the genetic differences among four isolates of Trichinella including a new strain of Trichinella spiralis (ISS 623) recently found from a human case who took a... -
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- Kearns-Sayre Syndrome with a Large Deletion in Mitochondrial DNA
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Kim SH, Hwang JH, Chung KW, Kim HJ, Kim JY, Park KD, Sunwoo IN, Choi BO
- KMID: 1572460
- J Korean Neurol Assoc.
- 2006 Jun;24(3):260-264.
Mitochondrial DNA (mtDNA) deletions have been found in a majority of patients with Kearns-Sayre syndrome (KSS). The proband, a 14-year-old male, presented with retinitis pigmentosa, bilateral ptosis with an external... -
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- Analysis of trinucleotide repetitive sequences for Korean patients with spinocerebellar ataxia types 8, 12, and 17
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Kim GH, Chung SJ, Ryu HS, Kim J, Lee JJ, Choi SH, Lee J, Lee BH, Choi JH, Yoo HW
- KMID: 2055588
- J Genet Med.
- 2015 Jun;12(1):38-43.
- doi: 10.5734/JGM.2015.12.1.38
PURPOSE: Spinocerebellar ataxias (SCAs) are progressive neurodegenerative disorders with diverse modes of inheritance. There are several subtypes of SCAs. SCA 8, SCA 12, and SCA 17 are the less common... -
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- Comparison of Sensitivity and Specificity of the Polymerase Chain Reaction for the M. tuberculois in CSF of Patients,Diagnosed as Tuberculous Meningitis and of Controls
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Kim KK, Kim JS, Whang YM, Lee MC, Song IS, Kim IS
- KMID: 1686771
- J Korean Neurol Assoc.
- 1993 Sep;11(3):392-403.
The diagnostic value of the DNA polymerase chain reaction for the detection of M. tuberculosis in tuberculous meningitis uas established by using cerebrospinal fluids obtained from 7 bacteriologically confirmed patients... -
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- The Present and Future of Molecular Epidemiology in Tuberculosis
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Park YK
- KMID: 2168624
- J Bacteriol Virol.
- 2011 Jun;41(2):77-82.
- doi: 10.4167/jbv.2011.41.2.77
Molecular epidemiology has been initiated for the confirmation of transmission link among tuberculosis patients. IS6110 restriction fragment length polymorphisms (RFLP) technique has been used as an excellent tool to discriminate... -
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- Epidemiological Investigation of an Outbreak of Escherichia coli Infections in Neonatal Intensive Care Unit of a University Hospital
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Oh HR, Moon DS, Jang SJ, Li XM, Kim DM, Park SG, Park G, Park YJ
- KMID: 1480980
- Korean J Clin Microbiol.
- 2008 Oct;11(2):123-128.
- doi: 10.5145/KJCM.2008.11.2.123
BACKGROUND: In July 2007, three neonates in the neonatal intensive care unit (NICU) of Chosun University Hospital expired due to Escherichia coli sepsis. An E. coli outbreak was suspected. METHODS: To... -
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