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Purturbation of Th1 / Th2 Balance by Interleukin 4 Receptor alpha Variant Q576R in Rheumatic Disease

Hwang SH, Youn JH, Cho CS, Min JK, Kim WU, Park SH, Kim HY

  • KMID: 1572925
  • Korean J Immunol.
  • 2000 Mar;22(1):9-15.
No abstract available.
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IL-4/IL-13 Cytokine and Receptor in Asthma

Yang ES

  • KMID: 2314355
  • Pediatr Allergy Respir Dis.
  • 2005 Mar;15(1):1-11.
Asthma is a chronic allergic inflammatory disease of lung. The initiation and progression of asthma is dependent on the cytokines interleukin (IL) -4 and IL-13 acting through related receptor complexes....
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Interleukin-4 Receptor Expression on Human Renal Cell Carcinoma Cell Lines by a Reverse Transcription-Polymerase Chain Reaction

Cheon J, Chung DJ, Choi JB, Koh SK, Sohn JW

  • KMID: 1913970
  • Korean J Urol.
  • 1995 Feb;36(2):121-127.
Recently interleukin-4 (IL-4) has been suggested to be a promising therapeutic agent for the malignant tumors of both murine and human origin. The effect of IL-4 is mediated by IL-4...
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Two Distinxt Apoptotic Pathway in Human Monocytes Mediated by IL-4 and Fas

Um HD

  • KMID: 1557247
  • Korean J Immunol.
  • 1998 Dec;20(4):405-410.
Apoptosis has ernerged as a key mechanism for regulating the number of leukocytes at sites of inflammation. Besides withdrawal of inflammatory stimuli, apoptosis of human monocytes can be directly triggered...
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Essential roles for ID-1 motif of interleukin-4 receptor alpha chain in interleukin-4 signaling

Youn J, Lee KH, Hwang WY, Paik DJ, Chung HS

  • KMID: 2285854
  • J Asthma Allergy Clin Immunol.
  • 2003 Jun;23(2):372-384.
BACKGROUND: Interleukin (IL)-4 is a pleiotropic cytokine that plays an important role in the pathogenesis of the allergic inflammation and asthma. Upon IL-4 receptor (IL-4R) engagement, a variety of signaling...
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A Study of Susceptibility between Allergic Rhinitis and IL-4 Receptor alpha Gene Polymorphism Study in Korean

Lee JH, Choi TW, Lee JH, Lee SH, Jeong HM, Min JY, Kim JJ

  • KMID: 2276463
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Aug;48(8):1004-1007.
BACKGROUND AND OBJECTIVES: The IL-4 receptor (IL-4R) gene has been suggested as a candidate gene for atopic diseases. The IL-4R consists of two subunits: the alpha chain (IL-4Ralpha), which is...
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Association of IL-4, IL-4 Receptor alpha Polymorphisms and Gene-gene Interaction in Atopic Asthma

  • KMID: 2234223
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Dec;24(4):385-393.
BACKGROUND: Atopy is a major risk factor in the development of asthma. Interleukin (IL)-4 and the IL-4 receptor alpha (IL-4R alpha ) play crucial roles for the binding and signal...
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IL-4 Receptor alpha Polymorphisms May Be a Susceptible Factor for Work-Related Respiratory Symptoms in Bakery Workers

Hur GY, Ye YM, Koh DH, Kim SH, Park HS

PURPOSE: The IL-4 and IL-4 receptor alpha (IL-4Ralpha) genes are the key candidate genes for atopy and asthma susceptibility. Exposure to wheat flour can cause IgE sensitization and respiratory symptoms...
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