- Characteristics in Molecular Vibrational Frequency Patterns between Agonists and Antagonists of Histamine Receptors
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Oh SJ
- KMID: 2166496
- Genomics Inform.
- 2012 Jun;10(2):128-132.
- doi: 10.5808/GI.2012.10.2.128
To learn the differences between the structure-activity relationship and molecular vibration-activity relationship in the ligand-receptor interaction of the histamine receptor, 47 ligands of the histamine receptor were analyzed by structural... -
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- Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal
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Fabisiak A, WÅ‚odarczyk J, Fabisiak N, Storr M, Fichna J
- KMID: 2387824
- J Neurogastroenterol Motil.
- 2017 Jul;23(3):341-348.
- doi: 10.5056/jnm16203
Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis... -
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- The Effect of H1 and H2 Blockade on Cutaneous Histamine Response in Man
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Myung KB
- KMID: 1965719
- Ewha Med J.
- 1987 Jun;10(2):107-111.
- doi: 10.12771/emj.1987.10.2.107
Histamine-induced cutaneous wheal responses were measured in 24 healthy subjects. The effect of the potent H1 blocker, hydroxyzine HCI, the H2 blocker, cimetidine, and the two drugs in combination was... -
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- The role of H1- and H2-receptors in the effect of compound 48/80 in the asphyxiation and body temperature of mice
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Ulugol A, Karadag H, Dokmeci D, Dokmeci I
- KMID: 2069425
- Yonsei Med J.
- 1996 Apr;37(2):97-103.
- doi: 10.3349/ymj.1996.37.2.97
Contribution of histamine H1- and H2-receptors to the effect of compound 48/80, a potent histamine releaser, upon asphyxiation and body temperature in mice was investigated in the present experiments. Compound... -
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- The Modulatory Role of Spinally Located Histamine Receptors in the Regulation of the Blood Glucose Level in D-Glucose-Fed Mice
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Sim YB, Park SH, Kim SS, Kim CH, Kim SJ, Lim SM, Jung JS, Ryu OH, Choi MG, Suh HW
- KMID: 2285489
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):41-46.
- doi: 10.4196/kjpp.2014.18.1.41
The possible roles of spinal histamine receptors in the regulation of the blood glucose level were studied in ICR mice. Mice were intrathecally (i.t.) treated with histamine 1 (H1) receptor... -
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- Histamine Promotes the Release of Interleukin-6 via the H1R/p38 and NF-kappaB Pathways in Nasal Fibroblasts
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Park IH, Um JY, Cho JS, Lee SH, Lee SH, Lee HM
- KMID: 2260180
- Allergy Asthma Immunol Res.
- 2014 Nov;6(6):567-572.
- doi: 10.4168/aair.2014.6.6.567
PURPOSE: Based on the close relationship between histamine and interleukin 6 (IL-6), we hypothesized that histamine may regulate the production of cytokines, such as IL-6, during allergic inflammation. Here, we... -
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- A Case of Hemodynamically Unstable Bradycardia after Risperidone Overdose
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Kwon BJ, Kim DB, Yang JH, Jang SW, Cho EJ, Seung KB, Rho TH, Kim JH, Choi KB
- KMID: 2332668
- J Korean Soc Emerg Med.
- 2009 Aug;20(4):453-457.
Risperidone is an atypical antipsychotic medication commonly used to treat psychotic illness, such as schizophrenia. It has strong serotonin and dopamine receptor antagonism and antagonist activity at alpha-adrenergic receptors and... -
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- Olopatadine ophthalmic solution suppresses substance P release in the conjunctivitis models
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Tamura T
- KMID: 2397364
- Asia Pac Allergy.
- 2012 Apr;2(2):115-121.
- doi: 10.5415/apallergy.2012.2.2.115
BACKGROUND: Olopatadine hydrochloride ophthalmic solutions are treated for allergic conjunctival diseases that are a selective histamine H1 receptor antagonist and an inhibitor of the release of mediators including histamine from... -
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- Evaluation of symptoms and symptom combinations in histamine intolerance
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Schnedl WJ, Lackner S, Enko D, Schenk M, Holasek SJ, Mangge H
- KMID: 2454752
- Intest Res.
- 2019 Jul;17(3):427-433.
- doi: 10.5217/ir.2018.00152
BACKGROUND/AIMS: Food intolerance/malabsorption, particularly histamine intolerance (HIT), may cause nonspecific functional gastrointestinal and extraintestinal symptoms. We evaluated gastrointestinal and extraintestinal symptoms in patients with HIT. METHODS: In an analysis of outpatients'... -
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- Prevention of ischemia-reperfusion injury in rat skin island flap: comparison of histamine receptor blocking agents with l-arginine
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Seo YK, Kim UK
- KMID: 2400581
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2006 Jul;28(4):287-294.
Vascular thrombosis and ischemic necrosis still remain the most significant threats to the survival of free flaps. To date, neutrophils have been implicated in the pathogenesis of postischemic injury. Several... -
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- Histamine and spontaneously released mast cell granules ffect the cell growth of human hepatocellular carcinoma cells
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Lampiasi N, Azzolina A, Montalto G, Cervello M
- KMID: 1047079
- Exp Mol Med.
- 2007 Jun;39(3):284-294.
The role of mast cells in tumor growth is still controversial. In this study we analyzed the effects of both histamine and pre-formed mediators spontaneously released by mast cells on... -
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- Block of hERG K+ Channel by Classic Histamine H1 Receptor Antagonist Chlorpheniramine
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Hong HK, Jo SH
- KMID: 2071674
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):215-220.
- doi: 10.4196/kjpp.2009.13.3.215
Chlorpheniramine is a potent first-generation histamine H1 receptor antagonist that can increase action potential duration and induce QT prolongation in several animal models. Since block of cardiac human ether-a-go-go-related gene... -
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- Evaluation of Thioperamide Effects Using Rat's Trachea Model
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Chiu FH, Wang HW
- KMID: 2278515
- Clin Exp Otorhinolaryngol.
- 2013 Mar;6(1):12-17.
OBJECTIVES: Thioperamide is used as an antagonist to the histamine H3 receptor. During administration of the drug, the trachea may be affected via nasal or oral inhalation. This study was... -
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- Treatment of Multiple Warts with High Dose Cimetidine Therapy
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Kim KH, Chung KY
- KMID: 2303058
- Korean J Dermatol.
- 2002 Nov;40(11):1374-1378.
BACKGROUND: Warts are often a difficult treatment problem for dermatologists. Cimetidine is a H2 histamine receptor antagonist that has been used mainly to treat peptic ulcer disease. The successful use... -
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- Effects of Antidepressants on Sleep
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Kim GH, Yang CK
- KMID: 2287190
- Korean J Psychopharmacol.
- 2006 Jul;17(4):325-334.
The diverse effects of antidepressants on sleep are mediated by their agonistic or antagonistic properties on specific neurotransmitters: the catecholamine, serotonergic, cholinergic, and histaminergic neurotransmitter systems, which also regulate the... -
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- H2 Receptor-Mediated Relaxation of Circular Smooth Muscle in Human Gastric Corpus: the Role of Nitric Oxide (NO)
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Lee SE, Kim DH, Kim YC, Han JH, Choi W, Kim CH, Jeong HW, Park SM, Yun SJ, Choi SY, Sung R, Kim YH, Yoo RY, Sun PH, Kim H, Song YJ, Xu WX, Yun HY, Lee SJ
- KMID: 2285542
- Korean J Physiol Pharmacol.
- 2014 Oct;18(5):425-430.
- doi: 10.4196/kjpp.2014.18.5.425
This study was designed to examine the effects of histamine on gastric motility and its specific receptor in the circular smooth muscle of the human gastric corpus. Histamine mainly produced... -
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- Treatment of Molluscum Contagiosum with High Dose Cimetidine Therapy
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Chang JY, Chung KY, Chung WG
- KMID: 2248921
- Korean J Dermatol.
- 2006 Aug;44(8):937-941.
BACKGROUND: Molluscum contagiosum is often a difficult problem for dermatologists to treat. Cimetidine is a H2 histamine receptor antagonist that has been used mainly to treat peptic ulcer disease. The... -
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- Treatment of Verruca Plana with High Dose Cimetidine Therapy
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Park CO, Chung KY, Chung WG
- KMID: 2302642
- Korean J Dermatol.
- 2005 Apr;43(4):475-479.
BACKGROUND: It is often a difficult problem for dermatologists to treat verruca plana. Cimetidine is a H2 histamine receptor antagonist that has been used mainly to treat peptic ulcer disease.... -
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- Role of Endogenous Histamine on the Pathogenesis in the Endotoxin-Induced Acute Lung Injury
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Kim TH, Kim EK, Yoon HJ, Kim MJ, Choi JE, Oh YM, Shim TS, Lim CM, Lee SD, Kim WS, Kim DS, Kim WD, Koh Y
- KMID: 1883786
- Tuberc Respir Dis.
- 2003 Jan;54(1):91-103.
- doi: 10.4046/trd.2003.54.1.91
BACKGROUND: Histamine is widely distributed in the lung. It increases capillary permeability and the P-selectin expression on vascular endothelial cell surfaces. We studied the role of endogenous histamine on the... -
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- Investigation of the antiallergic activity of olopatadine on rhinitis induced by intranasal instillation of antigen in sensitized rats using thermography
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Tamura T
- KMID: 2397432
- Asia Pac Allergy.
- 2011 Oct;1(3):138-144.
- doi: 10.5415/apallergy.2011.1.3.138
BACKGROUND: The main symptoms of allergic rhinitis (AR) are sneezing, rhinorrhea and nasal obstruction. It was reported that the nasal skin temperature after intranasal administration of histamine or grass pollen... -
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