- Anethesia and Glutamate Receptors
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Do SH
- KMID: 1482459
- Hanyang Med Rev.
- 2008 Nov;28(4):28-31.
Glutamate receptors represent major excitatory neurotransmission. Besides anesthesia, pain, memory and learning and neurotoxicity (excitotoxicity)are closely associated with the glutamate receptor, especially the NMDA receptor. Ketamine, an NMDA receptor antagonist,... -
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- The ontogeny of excitatory amino acid receptors in the rat brain quantitative autoradiographic study: I. N-methyl-D-aspartate receptors
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Lee HS
- KMID: 1686775
- Korean J Anat.
- 1991 Sep;24(3):344-355.
No abstract available. -
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- Newer Antipsychotics:Serotonin and Glutamate Receptor Related Drugs
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Kim CH
- KMID: 1607279
- Korean J Psychopharmacol.
- 2001 Jun;12(2):115-123.
Several decades of research attempting to explain schizophrenia regarding dopamine hyperactivity hypothesis have produced disappointing results. New hypotheses focusing on serotonin-dopamine interactions and hypofunction of the NMDA glutamate transmitter system... -
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- Effect of Brain-derived Neurotrophic Factor on Excitatory Synaptic Transmission in Hippocampal Neurons
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Song DK, Son EI, Hong YS, Bae JH, Park WK
- KMID: 1546027
- Korean J Aerosp Environ Med.
- 1999 Jun;9(2):192-197.
Brain-derived neurotrophic factor (BDNF) rapidly enhances synaptic transmission among the hippocampal neurons in the resting state. This mechanism may be due to the phosphorylation of NMDA receptors through its Trkb... -
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- Expression of Glutamate Receptors in Experimental Rat Model of Chronic Glaucoma
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Kim JH, Park CK
- KMID: 2208401
- J Korean Ophthalmol Soc.
- 2006 Mar;47(3):468-476.
PURPOSE: To investigate the changes of glutamate receptor expressions in the retina of the chronic ocular hypertension model of chronic glaucoma. METHODS: We performed quantification and localization of glutamate receptors... -
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- Physiological and pharmacological characterization of glutamate and GABA receptors in the retina
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Yang XL, Shen Y, Han MH, Lu T
- KMID: 2071547
- Korean J Physiol Pharmacol.
- 1999 Oct;3(5):461-469.
Glutamate and gamma-aminobutyric acid (GABA) are major excitatory and inhibitory neurotransmitters in the vertebrate retina, respectively. Using the whole-cell patch clamp technique and a rapid solution changer, glutamate and GABA receptors have been... -
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- Increases in Effective Cleft Glutamate Concentration During Expression of LTP
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Jung SH, Choi S
- KMID: 1615001
- Korean J Physiol Pharmacol.
- 2002 Apr;6(2):113-120.
Long-term potentiation (LTP) at hippocampal CA3-CA1 synapses is often associated with increases in quantal size, traditionally attributed to enhanced availability or efficacy of postsynaptic glutamate receptors. However, augmented quantal size... -
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- Expression of Glutamate Receptors in the Medial Vestibular Nuclei following Acute Hypotension
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Lee JH, Choi MA, Choi DO, Kim BK, Hong SM, Park BR
- KMID: 1518518
- J Korean Bal Soc.
- 2007 Jun;6(1):29-35.
Acute hypotension induced excitation of electrical activities and expression of c-Fos protein and pERK in the vestibular nuclei. In this study, to investigate the excitatory signaling pathway in the vestibular... -
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- Mechanism of Glutamate-induced[Ca2+]i Increase in Substantia Gelatinosa Neurons of Juvenile Rats
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Jung SJ, Choi JS, Kwak J, Kim J, Kim JW, Kim SJ
- KMID: 2285271
- Korean J Physiol Pharmacol.
- 2003 Apr;7(2):53-58.
The glutamate receptors (GluRs) are key receptors for modulatory synaptic events in the central nervous system. It has been reported that glutamate increases the intracellularCa (2+) concentration ([Ca2+]i) and induces... -
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- Psychiatric Implication for the Regulation of AMPA Receptor
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Oh D, Lee E
- KMID: 2299868
- Korean J Biol Psychiatry.
- 2013 Feb;20(1):1-5.
Glutamate receptors are important components of synaptic transmission in the nervous system. Especially, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors mediate most abundant excitatory synaptic transmission in the brain. There is elaborate... -
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- The Temporospatial Distribution of Glutamate Receptors and the Effect of MK-801 on Glutamate Receptors Activation in Kainate-induced Seizure Model: Quantitative Receptor Autoradiography of Ionotropic Glutamate Receptors
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Kim MK, Kim BC, Sohn EJ, Cho KH, Lee MC
- KMID: 2342953
- J Korean Neurol Assoc.
- 2002 Mar;20(2):179-186.
BACKGROUND: Excitotoxicity and epileptogenesis have often been associated with glutamate receptor activation. Some evidence indicates that selective down regulation of AMPA receptor may be the mechanism of delayed neuronal cell... -
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- Connecting the dots between SHP2 and glutamate receptors
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Ryu HH, Kim SY, Lee YS
- KMID: 2471034
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):129-135.
- doi: 10.4196/kjpp.2020.24.2.129
SHP2 is an unusual protein phosphatase that functions as an activator for several signaling pathways, including the RAS pathway, while most other phosphatases suppress their downstream signaling cascades. The physiological... -
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- Low Non-NMDA Receptor Current Density as Possible Protection Mechanism from Neurotoxicity of Circulating Glutamate on Subfornical Organ Neurons in Rats
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Chong W, Kim SN, Han SK, Lee SY, Ryu PD
- KMID: 2285570
- Korean J Physiol Pharmacol.
- 2015 Mar;19(2):177-181.
- doi: 10.4196/kjpp.2015.19.2.177
The subfornical organ (SFO) is one of circumventricular organs characterized by the lack of a normal blood brain barrier. The SFO neurons are exposed to circulating glutamate (60~100 microM), which... -
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- Action of Mitochondrial Substrates on Neuronal Excitability in Rat Substantia Gelatinosa Neurons
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Lee HI, Chun SW
- KMID: 2385806
- Int J Oral Biol.
- 2017 Jun;42(2):55-61.
- doi: 10.11620/IJOB.2017.42.2.055
Recent studies indicate that mitochondria are an important source of reactive oxygen species (ROS) in the spinal dorsal horn. In our previous study, application of malate, a mitochondrial electron transport... -
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- Electrophysiological Characterization of AMPA and NMDA Receptors in Rat Dorsal Striatum
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Jeun SH, Cho HS, Kim KJ, Li QZ, Sung KW
- KMID: 2071673
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):209-214.
- doi: 10.4196/kjpp.2009.13.3.209
The striatum receives glutamatergic afferents from the cortex and thalamus, and these synaptic transmissions are mediated by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) and N-methyl-D-aspartate (NMDA) receptors. The purpose of this study was to... -
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- Correlation between mEPSC Amplitude and Rise Time upon the Blockade of AMPA Receptor Desensitization at Hippocampal Synapses
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Jung SH, Choi S
- KMID: 1614994
- Korean J Physiol Pharmacol.
- 2002 Apr;6(2):81-86.
Conventional views of synaptic transmission generally overlook the possibility of "postfusional- control" the regulation of the speed or completeness of transmitter release upon vesicular fusion. However, such regulation often occurs... -
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- Effects of Apigenin on Glutamate-induced [Ca2+]i Increases in Cultured Rat Hippocampal Neurons
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Han JH, Kim KJ, Jang HJ, Jang JH, Kim MJ, Sung KW, Rhie DJ, Jo YH, Hahn SJ, Lee MY, Yoon SH
- KMID: 1486142
- Korean J Physiol Pharmacol.
- 2008 Apr;12(2):43-49.
- doi: 10.4196/kjpp.2008.12.2.43
Flavonoids have been shown to affect calcium signaling in neurons. However, there are no reports on the effect of apigenin on glutamate-induced calcium signaling in neurons. We investigated whether apigenin... -
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- Dietary Glutamate: Interactions With the Enteric Nervous System
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Wang GD, Wang XY, Xia Y, Wood JD
- KMID: 2381148
- J Neurogastroenterol Motil.
- 2014 Jan;20(1):41-53.
BACKGROUND/AIMS: Digestion of dietary protein elevates intraluminal concentrations of glutamate in the small intestine, some of which gain access to the enteric nervous system (ENS). Glutamate, in the central nervous... -
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- Type II and III Taste Bud Cells Preferentially Expressed Kainate Glutamate Receptors in Rats
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Lee SB, Lee CH, Kim SN, Chung KM, Cho YK, Kim KN
- KMID: 2285381
- Korean J Physiol Pharmacol.
- 2009 Dec;13(6):455-460.
- doi: 10.4196/kjpp.2009.13.6.455
Glutamate-induced cobalt uptake reveals that non-NMDA glutamate receptors (GluRs) are present in rat taste bud cells. Previous studies involving glutamate induced cobalt staining suggest this uptake mainly occurs via kainate... -
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- The Changes of Glutamate Receptor in Kindled Rats : Metabotropic Glutamate Receptor
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Jung DS, Kim HK, Sohn WS
- KMID: 2333363
- J Korean Epilepsy Soc.
- 2001 Dec;5(2):124-130.
PURPOSE: Kindling refers to a process whereby repeated applications of an initially subconvulsive electrical or chemical stimulus to animals lead to persistent epileptogenic in generalized seizures. Metabotropic glutamate receptors (mGluRs)... -
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