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Crosstalk between glucocorticoid receptor and NF-kappaB signaling pathways

Lee KY

  • KMID: 2054860
  • J Asthma Allergy Clin Immunol.
  • 2000 Oct;20(5):675-683.
No abstract available.
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Mechanisms of transcriptional repression by glucocorticoid receptor

Jee YK

  • KMID: 2285889
  • J Asthma Allergy Clin Immunol.
  • 2002 Jun;22(2):389-398.
No abstract available.
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Noise Induced Changes of Glucocorticoid Receptors in Rat Cocohlea

You JS, Lim HH, Choi JO

  • KMID: 2274304
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Feb;40(2):277-285.
It has been suggested that glucocorticoid receptors are present in inner ear tissues and may act in stress related mechanism of cochlea. The purpose of this study was to determine...
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Na+ Homeostasis in the Inner Ear

Kim SH, Kim SC

Na+ homeostasis in the inner ear is important to maintain normal hearing and balance. Na+ transport in the inner ear is reported to be occurred in non-sensory epithelium of inner...
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Mechanisms of Glucocorticoid Action in Chronic Rhinosinusitis

Lee SH

The innate immune system and its complex interplay with the adaptive immune system are increasingly being recognized as important factors in the pathogenesis of chronic rhinosinusitis (CRS). Adaptive immune components,...
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Secondary Adrenal Insufficiency Associated with Megestrol Acetate in a Patient with Lung Cancer

Park JC, Park SY

  • KMID: 2319192
  • Tuberc Respir Dis.
  • 2009 Jul;67(1):47-51.
Loss of appetite is an important factor in the quality of life for advanced cancer patients. Megestrol acetate is used to stimulate appetite, but it can cause suppression of the...
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Effects of Dexamethasone on Mucins of Human Corneal Epithelial Cells

Jun BS, Seo KY, Kim EK, Lee JB

  • KMID: 2206309
  • J Korean Ophthalmol Soc.
  • 2002 Dec;43(12):2527-2533.
PURPOSE: To evaluate whether mucin gene expression is regulated by glucocorticoid hormone in cultured human corneal epithelial cells (HCECs). The effects of dexamethasone on the expression of MUC1 and MUC4,...
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Sequential alterations of glucocorticoid receptors in the hippocampus of STZ-treated type 1 diabetic rats

Shin JH, Seong JK, Yi SS

Type 1 diabetes is a common metabolic disorder accompanied by increased blood glucose levels along with glucocorticoid and cognitive deficits. The disease is also thought to be associated with environmental...
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Depression as an Inflammatory Disease

Song HR, Woo YS, Bahk WM

  • KMID: 2287457
  • Korean J Psychopharmacol.
  • 2013 Jan;24(1):5-10.
Inflammation is an immune response engaged with the reciprocal interactions among the neural, endocrine and immune system. From this psychoneuroimmunological view, inflammation is one of important allostatic loads contributory to...
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Effect of p16 on glucocorticoid response in a B-cell lymphoblast cell line

Kim SY, Lee KY, Jeong DC, Kim HK

PURPOSE: It has been suggested that p16 has a role in glucocorticoid (GC)-related apoptosis in leukemic cells, but the exact mechanisms have yet to be clarified. We evaluated the relationship...
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Proliferative and Synthetic Responses of Airway Smooth Muscle in Asthma

Shim JY

  • KMID: 1763535
  • Korean J Pediatr.
  • 2005 Jun;48(6):580-587.
New evidence is emerging that airway smooth muscle (ASM) may act as an immunomodulatory cell by providing pro-inflammatory cytokines and chemokines, polypeptide growth factors, extracellular matrix proteins, cell adhesion receptors...
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Effects of neonatal footshock stress on glucocorticoid and 5-HT2A/2C receptor bindings and exploratory behavior

Kim DG, Lee S, Kang DW, Lim JS

  • KMID: 2071826
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):677-685.
To investigate the effects of neonatal stress on behavior and neurochemistry, rats were exposed to the footshock stress on postnatal day (PND) 14 or PNDs 14 and 21. Rats were exposed to...
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Transcriptional Regulation of Pyruvate Dehydrogenase Kinase

Jeong JY, Jeoung NH, Park KG, Lee IK

The pyruvate dehydrogenase complex (PDC) activity is crucial to maintains blood glucose and ATP levels, which largely depends on the phosphorylation status by pyruvate dehydrogenase kinase (PDK) isoenzymes. Although it...
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Role of Glucocorticoid Receptor on Insulin Secretion and Synthesis in INS-1 Cells

Yang JY, Kang MS, Song TH, Jeong IK, Seo PJ, Kim HJ

  • KMID: 2331791
  • J Korean Diabetes Assoc.
  • 2006 Nov;30(6):428-434.
BACKGROUND: Glucocorticoids play important roles in the regulation of glucose homeostasis. It is well known that glucocorticoids reduce hepatic and peripheral tissue sensitivity to insulin, but the roles of glucocorticoids...
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Direct Corticosteroid Modulation of GABAergic Neurons in the Anterior Hypothalamic Area of GAD65-eGFP Mice

Shin SY, Han TH, Lee SY, Han SK, Park JB, Erdelyi F, Szabo G, Ryu PD

Corticosterone is known to modulate GABAergic synaptic transmission in the hypothalamic paraventricular nucleus. However, the underlying receptor mechanisms are largely unknown. In the anterior hypothalamic area (AHA), the sympathoinhibitory center...
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Bifidobacterium longum and Lactobacillus helveticus Synergistically Suppress Stress-related Visceral Hypersensitivity Through Hypothalamic-Pituitary-Adrenal Axis Modulation

Ait-Belgnaoui A, Payard I, Rolland C, Harkat C, Braniste V, Théodorou V, Tompkins T

  • KMID: 2417281
  • J Neurogastroenterol Motil.
  • 2018 Jan;24(1):138-146.
  • doi: 10.5056/jnm16167
BACKGROUND/AIMS: Visceral pain and hypothalamic-pituitary-adrenal axis (HPA) dysregulation is a common characteristic in irritable bowel syndrome (IBS) patients. Previously, we reported that a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium...
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Expression of Glucocorticoid Receptor in Nasal Polyps and Nasal Mucosa

Kang JM, Cho JH, Won YS, Kim SS, Chang HS, Yoon HR

  • KMID: 2274726
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Jul;43(7):731-736.
BACKGROUND AND OBJECTIVES: Glucocorticoids are currently the most potent medication available for the treatment of nasal polyposis and allergic rhinitis, but exact mechanisms and cellular targets in the nasal mucosa...
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A Review of Postpartum Depression: Focused on Psychoneuroimmunological Interaction

Kim Y, Ahn S

PURPOSE: The purpose of this review was to describe a psychoneuroimmunology (PNI) framework for postpartum depression (PPD) and discuss its implications for nursing research and practice for postpartum women. METHODS: This...
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Differences of glucocorticoid and beta2-adrenergic receptor mRNA expression in steroid-dependent asthma

Bahn JW, Oh SY, Kim SH, Chang YS, Kim WK, Kim SH, Kim YK, Cho SH, Min KU, Kim YY

  • KMID: 2285856
  • J Asthma Allergy Clin Immunol.
  • 2003 Jun;23(2):394-403.
BACKGROUND: Steroid-dependency is one of Phenotypes of severe asthma. Because steroid-dependent asthmatics require long-term systemic steroids to control their symptoms. they have potentially increased risks to experience serious events caused...
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Changes in 11β-Hydroxysteroid Dehydrogenase and Glucocorticoid Receptor Expression in Kawasaki Disease

Wang J, Zhou N, Wu S, Zhang X, Su D

BACKGROUND AND OBJECTIVES: This study aims to investigate the significance of changes in the expression 11β-hydroxysteroid dehydrogenase (11β-HSD) and glucocorticoid receptor (GR) for the development of Kawasaki disease (KD). SUBJECTS AND...
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