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Chimeric antigen T cell receptor treatment in hematological malignancies

Ali N, FCPS Haematology

No abstract available.
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T cell costimulation by CD28, CTLA-4, and ICOS

Lee KM

T cells play a central role in the initiation and regulation of the immune response to foreign antigens. Full activation of T cells requires the engagement of T cell receptor complex...
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Emerging Co-signaling Networks in T Cell Immune Regulation

Jung K, Choi I

Co-signaling molecules are surface glycoproteins that positively or negatively regulate the T cell response to antigen. Co-signaling ligands and receptors crosstalk between the surfaces of antigen-presenting cells (APCs) and T...
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NF-kappaB Activation in T Helper 17 Cell Differentiation

Park SH, Cho G, Park SG

CD28/T cell receptor ligation activates the NF-kappaB signaling cascade during CD4 T cell activation. NF-kappaB activation is required for cytokine gene expression and activated T cell survival and proliferation. Recently,...
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First Case of Double T-Cell Receptor Alpha/Delta Rearrangements of t(11;14) and inv(14) and Subsequent JAK2 Rearrangement in a Patient With T-cell Acute Lymphoblastic Leukemia

Seol CA, Cho YU, Jang S, Park CJ, Lee JH, Seo EJ

No abstract available.
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Allograft Immune Reaction of Kidney Transplantation: Part 1. Mechanism of Allograft Rejection

Kang HG

  • KMID: 2322082
  • J Korean Soc Pediatr Nephrol.
  • 2008 Apr;12(1):23-29.
Kidney allograft transplantation is the most effective method of renal replacement for end stage renal disease patients. Still, it is another kind of 'disease', requiring immunosuppression to keep the allograft...
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Role of Fungal and Bacterial Superantigen in the Pathogenesis of Chronic Rhinosinusitis with Polyps

Shin SH

  • KMID: 2131931
  • J Rhinol.
  • 2008 Nov;15(2):98-102.
Chronic rhinosinusitis (CRS) is an inflammatory disorder with numerous predisposing factors, including genetics, anatomic anomalies, bacteria, and fungus. CRS with nasal polyps can be distinguished by an eosinophilic type inflammation...
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Molecular Features of Three Children Diagnosed With Early T-Cell Precursor Acute Lymphoblastic Leukemia

Park D, Kim M, Kim Y, Han K, Lee JW

No abstract available.
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Natural killer T cell and pathophysiology of asthma

Jang GC

Natural killer T (NKT) cell is a special type of T lymphocytes that has both receptor of natural killer (NK) cell (NK1.1, CD161c) and T cell (TCR) and express a...
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Simultaneous Occurrence of Angioimmunoblastic T-cell Lymphoma and Plasma Cell Leukemia

Jang MA, Lee ST, Kim HJ, Kim S, Kim SH

No abstract available.
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Two Cases of Subcutaneous Panniculitis-like T-cell Lymphoma

Chang SE, Lee WS, Lee MW, Sung KJ, Moon KC, Koh JK

  • KMID: 2251033
  • Korean J Dermatol.
  • 2001 Sep;39(9):1037-1040.
Subcutaneous panniculitis-like T-cell lymphoma(SPTCL) is a rare subtype of cutaneous T-cell lymphoma and needs to be differentiated from benign causes of panniculitis and other cutaneous T-cell lymphomas involving subcutis, especially...
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A Case of Nasal-type T/NK-cell Lymphoma Resembling Cellulitis

Park SJ, Kim SH, Lee ES

  • KMID: 2086479
  • Korean J Dermatol.
  • 2001 Aug;39(8):914-917.
T/NK-cell lymphoma shows biphenotype of the T-cell and NK-cell. This tumor is characterized by the absence of clonal rearrangement of T-cell receptor gene, frequent association with Epstein-Barr virus(EBV), poor clinical...
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Recent progress of elucidating the mechanisms of drug hypersensitivity

Hashizume

Recent technical approaches to investigating drug hypersensitivity have provided a great deal of information to solve the mechanisms that remain poorly understood. First, immunological investigations and in silico analysis have...
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Oral Tolerance Increased the Proportion of CD8+ T Cells in Mouse Intestinal Lamina Propria

Cho KA, Cha JE, Woo SY

BACKGROUND: Oral tolerance is defined by the inhibition of immune responsiveness to a protein previously exposed via the oral route. Protein antigens exposed via the oral route can be absorbed...
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Marked Increase of Circulating Double-Negative gammadelta T Cells in a Patient With Hydroa Vacciniforme-Like Lymphoma

Shin SY, Park CH, Cho D, Kim HJ, Kim SH

No abstract available.
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CD20 Positive T Cell Lymphoma Involvement of Skin

Lee KY, Jeon SY, Hong JW, Kim YH, Song KH, Kim KH

  • KMID: 2383261
  • Ann Dermatol.
  • 2011 Nov;23(4):529-535.
CD20 positive T cell lymphoma is a rare condition that is associated with the coexpressions of CD20 and T cell markers, such as, CD3, CD5, or UCHL-1. Positivity for CD20...
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Interleukin-17 in the Inflammatory Bowel Disease

Lee CR, Park SG

Inflammatory bowel diseases(IBD), including Crohn's disease and ulcerative colitis, are chronic inflammatory states of the intestinal tract. While the exact mechanisms inducing chronic inflammation are still unclear, it is hypothesized...
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A Case of Peripheral T-cell Lymphoma Showing Generalized Maculopapular Eruption

Jeong YI, Chang SE, Lee MW, Choi JH, Moon KC, Koh JK

  • KMID: 2086754
  • Korean J Dermatol.
  • 2003 Nov;41(11):1537-1540.
In revised WHO classification, "peripheral T-cell lymphoma, unspecified" includes pleomorphic small/medium-sized T cell lymphoma, pleomorphic type and immunoblastic type of CD30+ large cell lymphoma, CD30+ large cell lymphoma by EORTC...
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T-cell Large Granular Lymphocytic Leukemia: A Case Report

Song SH, Chung SM, Hwang DW, Choi JY, Yoo KD, Hong HS, Ahn YW, Roh YW, Lee JS, Park BB, Choi JH, Kim IS, Lee WS, Lee YY

T cell large granular lymphocytic leukemia (T-LGL leukemia) is defined as a clonal proliferative disorder of CD3+ cytotoxic T cells. T-LGL leukemia usually expresses CD3+, CD4-, CD8+, CD16+, CD56- and...
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Usage of T Cell receptor repertoire is restricted in synovial lymphocytes in rheumatoid arthritis

Kwon DH, Lee SK, Kim SJ, Choi IH

BACKGROUND: Rheumatoid arthritis is an autoimmune disease characterized by a chronic inflammatory process, primarily involving the synovial membrane of peripheral joints, where T cell activation is found. To address the...
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