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The Role of Serum HBV-RNA Levels as a Marker of Intrahepatic Viral and Histologic Activity

Kwon JH

No abstract available.
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Inhibition of hepatitis B virus replication by RNA interference

Park YG

No abstract available.
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Expression of Plus- and Minus-strand Viral RNA in Coxsackievirus B3-Infected A/J Mice

Hwang IS, Jun EJ, Ye JS, Joo CH, Lee H, Kim YK

In order to investigate the implication of viral replication in acute, subacute, and chronic infections of coxsackievirus B3 (CVB3), we examined the histopathological changes and plus- and minus-strand viral RNA...
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KASL clinical practice guidelines: management of hepatitis C

The Korean Association for the Study of the Liver (KASL)

No abstract available.
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Comparison of RNA Extraction Kits for Detection of HCV RNA

Cho SS, Jang SJ, Lym YM, Moon DS, Park YJ

  • KMID: 2055433
  • J Clin Pathol Qual Control.
  • 2000 Dec;22(2):287-292.
BACKGROUND: The efficiency of RNA isolation method is one of the important factors in hepatitis C virus (HCV) reverse transcription-polymerase chain reaction (RT-PCR) optimization. The standard methods for RNA isolation...
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Assessment of Porcine Reproductive and Respiratory Syndrome Virus RNA Load in Sera and Tissues during Acute Infection

Shin JH, Molitor TW

  • KMID: 1095365
  • J Vet Sci.
  • 2002 Jun;3(2):75-85.
Porcine reproductive and respiratory syndrome virus (PRRSV) RNA load in sera and tissues during acute phase of infection was evaluated using a PCR- based quantitative assay. More than 80% of...
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Predictors of spontaneous viral clearance and outcomes of acute hepatitis C infection

Cho YK, Kim YN, Song BC

BACKGROUND/AIMS: This study evaluated the predictors of spontaneous viral clearance (SVC), as defined by two consecutive undetectable hepatitis C virus (HCV) RNA tests performed > or =12 weeks apart, and...
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Biochemical properties of full-length hepatitis C virus RNA-dependent RNA polymerase expressed in insect cells

Choi HB, Kim YG, Oh JW

  • KMID: 1119328
  • Exp Mol Med.
  • 2003 Dec;35(6):475-485.
The hepatitis C virus (HCV) RNA-dependent RNA polymerase, NS5B protein, is the key viral enzyme responsible for replication of the HCV viral RNA genome. Although several full-length and truncated forms...
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Genome Size Constraint in Replication and Packaging of Turnip Yellow Mosaic Virus

Kim HB, Chae KH, Cho TJ

Turnip yellow mosaic virus (TYMV) is a spherical plant virus that has a single 6.3 kb positive strand RNA as a genome. Previously, we have made the recombinant TYMV construct...
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Isolation and Complete Nucleotide Analysis of a Noncytopathic BVDV Variant using a Dominant Selective Marker

Lee YM

  • KMID: 1572914
  • J Bacteriol Virol.
  • 2002 Mar;32(1):63-72.
Upon infection, bovine viral diarrhea virus (BVDV), one of the pestiviruses in the Flaviviridae family, is divided into two biotypes, cytopathic (cp) and noncytopathic (ncp). The mechanism of cytopathogenicity, however,...
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Rapid detection of deformed wing virus in honeybee using ultra-rapid qPCR and a DNA-chip

Kim JM, Lim SJ, Kim S, Kim M, Kim B, Tai TA, Kim S, Yoon B

Fast and accurate detection of viral RNA pathogens is important in apiculture. A polymerase chain reaction (PCR)-based detection method has been developed, which is simple, specific, and sensitive. In this...
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KASL clinical practice guidelines: Management of Hepatitis C

The Korean Association for the Study of the Liver (KASL)

No abstract available.
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Hepatitis C virus: virology and life cycle

Kim CW, Chang KM

Hepatitis C virus (HCV) is a positive sense, single-stranded RNA virus in the Flaviviridae family. It causes acute hepatitis with a high propensity for chronic infection. Chronic HCV infection can...
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Cysteine-Added Mutants of Turnip Yellow Mosaic Virus

Shin IS, Kim D, Cho TJ

Native turnip yellow mosaic virus (TYMV) is relatively unreactive to maleimide agents, indicating few reactive thiol groups on TYMV. In the present study, we aimed to construct TYMV mutants that...
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Antiviral Activity of Gemcitabine Against Echovirus 30 Infection in Vitro

Choi HJ, Song JH, Yoon K

Echovirus 30 is one of the major causes of meningitis in children and adults. The purpose of our current study was to investigate whether selected antiviral drugs could provide antiviral...
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Characterization of a Replication Element in the Coat Protein ORF of Turnip Yellow Mosaic Virus

Shin HI, Cho TJ

Turnip yellow mosaic virus (TYMV) is a non-enveloped icosahedral virus that has a single 6.3 kb positive-strand RNA as a genome. Previously, it was observed that the recombinant construct TY-eGFP2,...
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The Generation of Reassortants by Genetic Reassortment between Different Serotypes of Hantaviruses

Park MS, Chung DH, Lee PW

  • KMID: 1615426
  • J Bacteriol Virol.
  • 2003 Mar;33(1):69-80.
Hantaviruses are negative-strand RNA viruses that contain three segmented (L/M/S) genome and belong to the genus hantavirus of the family Bunyaviridae. Due to such an unique structure of segmented RNA...
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Sensing DNA Viruses and Bacteria by Intracellular DNA Sensors

Lee NR, Shin HB, Kim HI, Choi MS, Inn KS

The innate immune system confers first-line defense against various pathogens including bacteria and viruses. Early detection of invading pathogens by the host depends on a limited number of specific pattern...
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Hepatitis G virus

Jang SJ

  • KMID: 2425649
  • Korean J Clin Microbiol.
  • 1998 Sep;1(1):15-21.
Recently, two groups reported independently on the isolation of new positive-trand RNA viruses, designated hepatitis G virus (HGV) & GB virus C (GBV-C). Sequence analysis revealed that both genomes are...
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Establishment of reverse transcription polymerase chain reaction for detection of Getah virus infection in livestock

Lee SH, Yang DK, Kim HH, Choi SS, Cho IS

Getah virus (GETV) infection causes sporadic outbreaks of mild febrile illness in horses and reproductive failure in pigs. In this study, we established a reverse transcription polymerase chain reaction (RT-PCR)...
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