- Pathogenesis and Management of Serrated Polyps: Current Status and Future Directions
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Anderson J
- KMID: 2070073
- Gut Liver.
- 2014 Nov;8(6):582-589.
- doi: 10.5009/gnl14248
Hyperplastic or serrated polyps were once believed to have little to no clinical significance. A subset of these polyps are now considered to be precursors to colorectal cancers (CRC) in... -
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- Lack of Aberrant Methylation in an Adjacent Area of Left-Sided Colorectal Cancer
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Sambuudash O, Kim HS, Cho MY
- KMID: 2419080
- Yonsei Med J.
- 2017 Jul;58(4):749-755.
- doi: 10.3349/ymj.2017.58.4.749
PURPOSE: The molecular nature and the rate-limiting step of epigenetic field defects in the evolution of left-sided colorectal cancer (LCA) remain uncertain. MATERIALS AND METHODS: The methylation status of 27 candidate... -
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- CpG Island Methylator Phenotype-High Colorectal Cancers and Their Prognostic Implications and Relationships with the Serrated Neoplasia Pathway
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Rhee YY, Kim KJ, Kang GH
- KMID: 2412153
- Gut Liver.
- 2017 Jan;11(1):38-46.
- doi: 10.5009/gnl15535
The concept of a CpG island methylator phenotype (CIMP) was first introduced by Toyota and Issa to describe a subset of colorectal cancers (CRCs) with concurrent hypermethylation of multiple CpG... -
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- The effect of 5-aminoimidazole-4-carboxamide-ribonucleoside was mediated by p38 mitogen activated protein kinase signaling pathway in FRO thyroid cancer cells
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Kim WG, Choi HJ, Kim TY, Shong YK, Kim WB
- KMID: 2070111
- Korean J Intern Med.
- 2014 Jul;29(4):474-481.
BACKGROUND/AIMS: 5'-Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a cellular energy sensor that monitors intracellular AMP/adenosine triphosphate (ATP) ratios and is a key regulator of the proliferation and survival of... -
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