- A Novel KIT INDEL Mutation in Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1
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Lee JH, Park C, Kim SH, Shin MG
- KMID: 2373559
- Ann Lab Med.
- 2016 Jul;36(4):371-374.
- doi: 10.3343/alm.2016.36.4.371
No abstract available. -
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- Concomitance of P-gp/LRP Expression with EGFR Mutations in Exons 19 and 21 in Non-Small Cell Lung Cancers
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Wei H, Lu W, Li M, Zhang Q, Lu S
- KMID: 2466351
- Yonsei Med J.
- 2016 Jan;57(1):50-57.
- doi: 10.3349/ymj.2016.57.1.50
PURPOSE: Traditional chemotherapy is the main adjuvant therapy for the treatment of non-small cell lung cancer (NSCLC). However, the emergence of multi-drug resistance (MDR) has greatly restricted the curative effect... -
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- Activation of KRAS promotes the mesenchymal features of basal-type breast cancer
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Kim RK, Suh Y, Yoo KC, Cui YH, Kim H, Kim MJ, Kim IG, Lee SJ
- KMID: 2155402
- Exp Mol Med.
- 2015 Jan;47(1):e137.
- doi: 10.1038/emm.2014.99
Basal-type breast cancers are among the most aggressive and deadly breast cancer subtypes, displaying a high metastatic ability associated with mesenchymal features. However, the molecular mechanisms underlying the maintenance of... -
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- Functional characterization of human oncoprotein gankyrin in Zebrafish
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Kim SY, Hur W, Choi JE, Kim D, Wang JS, Yoon HY, Piao LS, Yoon SK
- KMID: 756281
- Exp Mol Med.
- 2009 Jan;41(1):8-16.
- doi: 10.3858/emm.2009.41.1.002
Gankyrin is an oncoprotein containing seven ankyrin repeats that is overexpressed in hepatocellular carcinoma (HCC). Gankyrin binds to Mdm2, which results in accelerated ubiquitylation via degradation of p53, and it... -
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- Mutational Analysis of KRAS, BRAF, and TP53 Genes of Ovarian Serous Carcinomas in Korean Women
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Cho YH, Kim DY, Kim JH, Kim YM, Kim KR, Nam JH, Kim YT
- KMID: 2396071
- Yonsei Med J.
- 2009 Apr;50(2):266-272.
PURPOSE: To assess the prevalence of KRAS, BRAF, and TP53 mutations in cases of low-grade and high-grade serous carcinomas and to evaluate the clinical outcomes of these morphologically distinct carcinomas.... -
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- Near-tetraploidy Acute Myeloid Leukemia with RUNX1-RUNX1T1 Rearrangement Due to Cryptic t(8;21)
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Im M, Lee JK, Lee DY, Hong YJ, Hong SI, Kang HJ, Chang YH
- KMID: 1781603
- Korean J Lab Med.
- 2009 Dec;29(6):510-514.
- doi: 10.3343/kjlm.2009.29.6.510
Tetraploidy or near-tetraploidy is a rare cytogenetic abnormality found in AML, and is divided into primary and secondary forms. The secondary tetraploidy or near-tetraploidy found in AML is known to... -
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- LIN28B confers radio-resistance through the posttranscriptional control of KRAS
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Jeong SH, Wu HG, Park WY
- KMID: 1099867
- Exp Mol Med.
- 2009 Dec;41(12):912-918.
- doi: 10.3858/emm.2009.41.12.097
To screen the differentially expressed microRNAs related to radio-resistance, we compared the microRNA profiles of lung cancer cells with different responses to ionizing radiation (IR). Of 328 microRNAs in microarray,... -
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- The Impact of Cigarette Smoking on the Frequency of and Qualitative Differences in KRAS Mutations in Korean Patients with Lung Adenocarcinoma
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Kim HR, Ahn JR, Lee JG, Bang DH, Ha SJ, Hong YK, Kim SM, Nam KC, Rha SY, Soo RA, Riely GJ, Kim JH, Cho BC
- KMID: 2158219
- Yonsei Med J.
- 2013 Jul;54(4):865-874.
- doi: 10.3349/ymj.2013.54.4.865
PURPOSE: This study was designed to determine the relationship of cigarette smoking to the frequency and qualitative differences among KRAS mutations in lung adenocarcinomas from Korean patients. MATERIALS AND METHODS: Detailed... -
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- A Novel Translocation t(1;5)(p32;q31) that Was Not Associated with the TAL1 Rearrangement in a Case of T Lymphoblastic Leukemia/Lymphoma
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Cho HS, Kim MK, Bae YK
- KMID: 1096970
- Korean J Lab Med.
- 2009 Jun;29(3):199-203.
- doi: 10.3343/kjlm.2009.29.3.199
Chromosome 1 band p32 (1p32) aberrations are common in T lymphoblastic leukemia/lymphoma (T-ALL/LBL). Two types of 1p32 aberrations include translocations with different partners and submicroscopic interstitial deletion. Both aberrations are... -
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- Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide
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Cha HS, Bae EK, Ahn JK, Lee J, Ahn KS, Koh EM
- KMID: 1078358
- Exp Mol Med.
- 2010 Jun;42(6):428-436.
- doi: 10.3858/emm.2010.42.6.044
Inadequate apoptosis contributes to synovial hyperplasia in rheumatoid arthritis (RA). Recent study shows that low expression of Puma might be partially responsible for the decreased apoptosis of fibroblast-like synoviocytes (FLS).... -
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