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Targeting the protein kinases for anti-cancer therapy

Bang SM

No abstract available.
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Role of Protein Kinase C in Normal and Preconditioned Myocardium

Na HS

No abstract available.
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Role of Mitogen Activated Protein Kinase and PI 3-kinase on Cell Proliferation in Pancreatic Cancer Cell Lines with K-ras Mutation

Ryu JK, Kim J, Chang YH, Lee WJ, Kim YT, Yoon YB, Kim CY

  • KMID: 2240269
  • Korean J Gastroenterol.
  • 2000 Sep;36(3):372-382.
No Abstract Available.
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Mitogen-activated Protein Kinases in Inflammation

Manzoor Z, Koh YS

Mitogen-activated protein kinases (MAPKs) play critical regulatory roles in the production of the pro-inflammatory cytokines and downstream signaling events which lead to inflammation. Inflammation is a primarily localized and protective...
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Role of 5´-AMP-Activated Protein Kinase Activators in Regulating Nuclear Factor Kappa B Signaling

Lee T

No abstract available.
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Effects of psychotropic drugs on phospholipase C and protein kinase C in vitro

Choi Y, Lee KY, Lee HY

  • KMID: 2197826
  • J Korean Neuropsychiatr Assoc.
  • 1992 Sep;31(5):837-845.
No abstract available.
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Involvement of Mitogen-Activated Protein Kinase in Aspirin-induced Expression of Cyclooxygenase-2 in Amnionic Cell Line WISH Cells

Je GH, Cha MS, Gwak JY

  • KMID: 2036197
  • Korean J Obstet Gynecol.
  • 2000 Dec;43(12):2191-2197.
No abstract available.
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The Role of Protein Kinase in Head and Neck Cancer

Chu HR

  • KMID: 2276486
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Oct;48(10):1198-1204.
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Mitogen-activated Protein Kinase Signaling in Inflammation-related Carcinogenesis

Manzoor Z, Koo JE, Koh YS

The role of mitogen-activated protein kinases (MAPKs) in regulation of inflammation is well known. MAPK family is activated by various stimuli and involved in transmitting extracellular signals to nucleus leading...
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Multiple Regulation of Roundabout (Robo) Phosphorylation in a Heterologous Cell System

Park HT

  • KMID: 1611238
  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):111-115.
Roundabout (Robo) is the transmembrane receptor for slit, the neuronal guidance molecule. In this study, the tyrosine phosphorylation of Robo was observed in Robo-transfected human embryonic kidney cells and developing...
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p21-Activated Kinases (PAKs) as a Therapeutic Target

Koo BS

p21-activated kinases (PAKs) are a family of serine/threonine protein kinases comprised of six isoform (PAK1-6), all of which are direct targets of the small GTPases Rac and Cdc42. PAKs have...
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Regulation of Protein Kinase in KCl-induced Contraction of Cat Gastric Smooth Muscle

Kim MS, Jo YH, Yoon SH, Hahn SJ, Sim SS, Shim HS, Rhie DJ, Kim SR

  • KMID: 2304693
  • Korean J Gastroenterol.
  • 1998 Sep;32(3):290-297.
BACKGROUND AND AIMS: Smooth muscle contraction and relaxation are suggested to be modulated by intracellular Ca2+, protein kinases and tyrosine kinases. To investigate whether protein kinases are invelved in the...
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Screening of protein kinase C-inhibiting herbs using TPA-induced adherence of HL-60 cell

Kim SH, Ahn JS, Kim SY, Yoo KH, Ahn BJ

  • KMID: 1694286
  • J Korean Cancer Assoc.
  • 1993 Feb;25(1):9-14.
No abstract available.
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Role of protein kinases on NF- kappaB activation and cell death in bovine cerebral endothelial cells

Ahn YS, Kim CH, Kim JH

  • KMID: 1917065
  • Korean J Physiol Pharmacol.
  • 1999 Feb;3(1):11-18.
Nuclear factor kappaB (NF- kappaB) activation is modulated by various protein kinases. Activation of NF- kappaB is known to be important in the regulation of cell viability. The present study investigated the effect...
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Analysis of Histopathology of the Irradiated Adult Rat Brain During First 3 Post-Irradiation Months: Expression of Protein Kinase C and the Role of Apoptosis in Radiation Encephalopathy

Koo H, Lee KJ

No abstract available in English.
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Letter to the Editor: 17Beta-estradiol Stimulates Glucose Uptake Through Estrogen Receptor and AMP-activated Protein Kinase Activation in C2C12 Myotubes (Korean J Obes 2016;25:190-6)

Kwak HB

No abstract available.
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Effect of kainic acid on the phosphorylation of mitogen activated protein kinases in rat hippocampus

Won JS, Lee JK, Choi SS, Song DK, Huh SO, Kim YH, Suh HW

  • KMID: 1607133
  • Korean J Physiol Pharmacol.
  • 2001 Dec;5(6):451-456.
In rat hippocampus, kainic acid (KA; 10 mg/kg; i.p.) increased the phosphorylated forms of ERK1/2 (p-ERK1/2) and Jun kinase1 (p-JNK1), but not p-JNK2 and p38 (p-p38). The preadministration with cycloheximide...
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A Role of Mitogen Activated Protein Kinases and Inflammatory Responses in Gender Differences in Kidney Ischemia Injury

Park KM, Han HJ

  • KMID: 2285245
  • Korean J Physiol Pharmacol.
  • 2002 Jun;6(3):155-160.
It is not known whether gender differences play a role in susceptibility to ischemic acute renal failure. Thus, we examined if there were any differences in susceptibility between male and...
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Regulation of exercise-stimulated glucose uptake in skeletal muscle

Koh HJ

AMP-activated protein kinase (AMPK) is a Ser/Thr kinase that has been thought to be an important mediator for exercise-stimulated glucose uptake in skeletal muscle. Liver kinase B1 (LKB1) is an...
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AMPK and Type 2 Diabetes Mellitus

Son HS

  • KMID: 2008286
  • J Korean Diabetes Assoc.
  • 2002 Dec;26(6):443-450.
No abstract available.
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