- Cleavage of purified neuronal clathrin assembly protein (CALM) by caspase 3 and calpain
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Kim JA, Kim HL
- KMID: 1457537
- Exp Mol Med.
- 2001 Dec;33(4):245-250.
The most efficient means of protein internalization from the membrane are through clathrin-coated pits, which concentrate protein interactions with the clathrin-associated assembly protein complex AP-2 and internalization signals in the... -
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- Homophilic interaction of the L1 family of cell adhesion molecules
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Wei CH, Ryu SE
- KMID: 1397445
- Exp Mol Med.
- 2012 Jul;44(7):413-423.
Homophilic interaction of the L1 family of cell adhesion molecules plays a pivotal role in regulating neurite outgrowth and neural cell networking in vivo. Functional defects in L1 family members... -
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- A molecular model of a point mutation (Val297Met) in the serine protease domain of protein C
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Song KS, Park YS, Choi JR, Kim HK, Park Q
- KMID: 755027
- Exp Mol Med.
- 1999 Mar;31(1):47-51.
A heterozygous GTG to ATG (Val297Met) mutation was detected in a patient with inherited protein C deficiency and deep vein thrombosis. Cosegregation of the mutation with protein C deficiency was observed through... -
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- The centrosomal localization of KM-HN-1 (MGC33607) depends on the leucine zipper motif and the C-terminal coiled-coil domain
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Park HJ, Seo HJ, Kim HW, Kim JS, Hwang SY, Seong YS
- KMID: 1091078
- Exp Mol Med.
- 2007 Dec;39(6):828-838.
KM-HN-1 is a C-terminal coiled-coil domain containing protein previously referred to as image clone MGC33607. This protein has been previously identified as a cancer/testis antigen and reported as nuclear and... -
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- Functional Role of Serine Residues of Transmembrane Dopamin VII in Signal Transduction of CB2 Cannabinoid Receptor
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Rhee MH
- KMID: 1095120
- J Vet Sci.
- 2002 Sep;3(3):185-191.
Using site-directed mutagenesis technique, I have replaced serine 285 and serine 292 with the alanine, and assessed the binding of agonist and signaling such as the inhibition of adenylyl cyclase... -
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- In Vitro and In Vivo Effect of Parathyroid Hormone Analogue (1-14) Containing alpha-amino-iso-butyric Acid Residue (Aib)1,3
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Rhee Y, Lee W, Lee EJ, Ma S, Park SY, Lim SK
- KMID: 1110745
- Yonsei Med J.
- 2006 Apr;47(2):214-222.
- doi: 10.3349/ymj.2006.47.2.214
Firstly, parathyroid hormone (1-14) [PTH (1-14)] analogue containing various alpha-amino-iso-butyric acid residue (Aib) was synthesized by exchanging the 1st and 3rd Ala residues of alpha carbon of PTH (1-14). This... -
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- Identification and Molecular Characterization of Parkin in Clonorchis sinensis
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Bai X, Kim TI, Lee JY, Dai F, Hong SJ
- KMID: 2381798
- Korean J Parasitol.
- 2015 Feb;53(1):65-75.
- doi: 10.3347/kjp.2015.53.1.65
Clonorchis sinensis habitating in the bile duct of mammals causes clonorchiasis endemic in East Asian countries. Parkin is a RING-between-RING protein and has E3-ubiquitin ligase activity catalyzing ubiquitination and degradation... -
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- Biochemical characterizations reveal different properties between CDK4/cyclin D1 and CDK2/cyclin A
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Kim DM, Yang K, Yang BS
- KMID: 1093615
- Exp Mol Med.
- 2003 Oct;35(5):421-430.
CDK2 and CDK4 known promoter of cell cycling catalyze phosphorylation of RB protein. Enzyme specificity between two CDKs that work at a different cell cycle phase is not clearly understood.... -
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- p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases
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El-Benna J, Dang PM, Gougerot-Pocidalo MA, Marie JC, Braut-Boucher F
- KMID: 1088596
- Exp Mol Med.
- 2009 Apr;41(4):217-225.
- doi: 10.3858/emm.2009.41.4.058
Phagocytes such as neutrophils play a vital role in host defense against microbial pathogens. The anti-microbial function of neutrophils is based on the production of superoxide anion (O2(.-)), which generates... -
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- Heterozygous Mutations of The Gene for Kir 1.1 (ROMK) in Antenatal Bartter Syndrome Presenting with Transient Hyperkalemia, Evolving to a Benign Course
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Cho JT, Guay-Woodford LM
- KMID: 1099795
- J Korean Med Sci.
- 2003 Feb;18(1):65-68.
- doi: 10.3346/jkms.2003.18.1.65
Bartter-like syndrome encompasses a set of inherited renal tubular disorders associated with hypokalemic metabolic alkalosis, renal salt wasting, hyperreninemic hyperaldosteronism, and normal blood pressure. Antenatal Bartter syndrome, a subtype of... -
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- The Critical Roles of Zinc: Beyond Impact on Myocardial Signaling
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Lee SR, Noh SJ, Pronto JR, Jeong YJ, Kim HK, Song IS, Xu Z, Kwon HY, Kang SC, Sohn EH, Ko KS, Rhee BD, Kim N, Han J
- KMID: 2285583
- Korean J Physiol Pharmacol.
- 2015 Sep;19(5):389-399.
- doi: 10.4196/kjpp.2015.19.5.389
Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile reactive zinc (Zn2+) is the key form of zinc involved in signal transductions, which are mainly driven... -
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- Immunogenetics of the HLA system
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Choo SY
- KMID: 1117730
- Yonsei Med J.
- 1991 Mar;32(1):1-8.
- doi: 10.3349/ymj.1991.32.1.1
The study of the HLA system was primarily initiated to understand the basis for the histocompatibility between recipients and tissue donors. HLA typing methods are being continuously improved and biochemical... -
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- Voltage Regulation of Connexin Channel Conductance
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Oh S, Bargiello
- KMID: 2352783
- Yonsei Med J.
- 2015 Jan;56(1):1-15.
- doi: 10.3349/ymj.2015.56.1.1
Voltage is an important parameter that regulates the conductance of both intercellular and plasma membrane channels (undocked hemichannels) formed by the 21 members of the mammalian connexin gene family. Connexin... -
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- Novel CLCN1 Mutations and Clinical Features of Korean Patients with Myotonia Congenita
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Moon IS, Kim HS, Shin JH, Park YE, Park KH, Shin YB, Bae JS, Choi YC, Kim DS
- KMID: 1783130
- J Korean Med Sci.
- 2009 Dec;24(6):1038-1044.
- doi: 10.3346/jkms.2009.24.6.1038
Myotonia congenita (MC) is a form of nondystrophic myotonia caused by a mutation of CLCN1, which encodes human skeletal muscle chloride channel (CLC-1). We performed sequence analysis of all coding... -
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