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An Experimental Study on the Efficacy of Vitamin E against Oxygen Toxicity

Lee SG, Lee SI, Cho SH, Yun DR

  • KMID: 2282238
  • Korean J Prev Med.
  • 1986 Nov;19(2):184-192.
Since the wide spread application of hyperbaric oxygenation in clinical setting, the problems of oxygen toxicity have been attracting a deep interest from the researchers on hyperbaric medicine as a...
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An experimental study on the effect of maltol against oxygen toxicity

Hwang SJ, Cho SH, Yon DR

  • KMID: 2282655
  • Korean J Prev Med.
  • 1993 Dec;26(4):551-564.
Since the widespread application of hyperbaric oxygenation in clinical medicine, the problems of oxygen toxicity have been attracting a deep interest from the researchers on hyperbaric medicine as a practical...
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An Experimental Study for Sunscreening Effect of Several Sunscreen Agents

Jang JE, Kook HI, Byun JH

The change of the skin are acute reaction of erythema or sunburn, and/or prolonged and accumulated exposure commonly associated with degenerative changes, skin, aging, actinic keratosis and carcinoma after exposure...
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The Protective Effects of Garlic against Carbon tetrachloride-induced Hepatotoxicity

Choi BS, Lee JM, Park JD, Hong YP

  • KMID: 2283257
  • Korean J Prev Med.
  • 2002 Aug;35(3):221-228.
OBJECTIVES: The purpose of this study was to find the protective effects of garlic on the halogenated hydrocarbon induced hepatotoxicities, and the possible protection mechanisms involved. METHODS: Male Sprague-Dawley rats received...
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The Effects of Diethyldithiocarbamate on the Metabolism and Hepatotoxicity of Trichloroethylene

Choi BS, Park JD, Hong YP

  • KMID: 2028185
  • Korean J Occup Environ Med.
  • 2002 Sep;14(3):257-269.
OBJECTIVES: The purpose of this study was to evaluate the trichloroethylene (TCE) metabolism, acute toxicity, and the effects of diethyldithiocarbamate (DDTC) on the acute toxicity in TCE-intoxicated rats. METHODS: TCE was...
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The Effect of Free Radical Scavengers on Reperfusion Injury after Testicular Torsion

Jung SY, Cho DH, Chun CS

  • KMID: 1913762
  • Korean J Urol.
  • 1996 Feb;37(2):121-125.
The free radicals generated during the ischemic/reperfusion period have been suggested as a possible cause for tissue damage in organs. This state was conducted to investigate protective effects of free...
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Radioprotective effect of mefenamic acid against radiation-induced genotoxicity in human lymphocytes

Hosseinimehr SJ, Nobakht R, Ghasemi A, Pourfallah TA

PURPOSE: Mefenamic acid (MEF) as a non-steroidal anti-inflammatory drug is used as a medication for relieving of pain and inflammation. Radiation-induced inflammation process is involved in DNA damage and cell...
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Gastrointestinal Risk Assessment in the Patients Taking Nonsteroidal Anti-inflammarory Drugs for Lumbar Spinal Disease

Lee BH, Shin BJ, Kim DJ, Lee JC, Suk KS, Park YS, Kim KW, Cho KJ, Shin KY, Koh MS, Moon SH

STUDY DESIGN: A cross-section observational study. OBJECTIVES: To evaluate the current prescription patterns of non-steroidal anti-inflammatory drugs (NSAIDs) and gastrointestinal (GI) risk assessment in patients with lumbar spine disease. SUMMARY OF LITERATURE...
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Trend in the Eradication Rates of Helicobacter pylori Infection Over the Last 10 Years in West Gyeonggi-do, Korea: A Single Center Experience

Park JS, Park JE, Oh BS, Yoon BW, Kim HK, Lee JW, Kim NH, Cho WS, Woo YS, Jahng J, Kim YS

BACKGROUND/AIMS: The eradication rate of Helicobacter pylori (H. pylori) has been decreasing recently in Korea due to antibiotics resistance. The aim of this study was to investigate the trend of...
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Protective Effects of Epigallocatechin Gallate After UV Irradiation of Cultured Human Lens Epithelial Cells

Heo J, Lee BR, Koh JW

PURPOSE: To evaluate the protective effects of epigallocatechin gallate (EGCG) against UV irradiation of cultured human lens epithelial cells. METHODS: We irradiated cultured human lens epithelial cells with...
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Protective Effects of Female Reproductive Factors on Lauren Intestinal-Type Gastric Adenocarcinoma

Kim SM, Min BH, Lee J, An JY, Lee JH, Sohn TS, Bae JM, Kim JJ, Kang WK, Kim S, Choi MG

PURPOSE: Gastric cancer shows a male predominance that might be explained by protective effects from estrogens in females. Two Lauren classification histological subtypes, intestinal and diffuse, have distinct carcinogeneses. The...
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Factors affecting drug-induced liver injury: antithyroid drugs as instances

Heidari R, Niknahad H, Jamshidzadeh A, Abdoli N

Methimazole and propylthiouracil have been used in the management of hyperthyroidism for more than half a century. However, hepatotoxicity is one of the most deleterious side effects associated with these...
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Protective Effects of Epigallocatechin Gallate after UV Irradiation in Cultured Human Retinal Pigment Epithelial Cells

Yang SW, Lee BR, Koh JW

PURPOSE: To evaluate the protective effects of Epigallocatechin gallate (EGCG) against UV irradiation in cultured human retinal pigment epithelial (RPE) cells. METHODS: UV irradiation was produced by a UV...
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Galpha12 Protects Vascular Endothelial Cells from Serum Withdrawal-Induced Apoptosis through Regulation of miR-155

Lee HJ, Lee EJ, Seo M

PURPOSE: Apoptosis of vascular endothelial cells is a type of endothelial damage that is associated with the pathogenesis of cardiovascular diseases such as atherosclerosis. Heterotrimeric GTP-binding proteins (G proteins), including...
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Therapeutic effect of topical application of curcumin during treatment of radiation burns in a mini-pig model

Kim J, Park S, Jeon BS, Jang WS, Lee SJ, Son Y, Rhim KJ, Lee SI, Lee SS

Curcumin protects the skin against radiation-induced epidermal damage and prevents morphological changes induced by irradiation skin, thereby maintaining the epidermal thickness and cell density of basal layers. In this study,...
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A Novel Synthetic Compound 3-Amino-3-(4-Fluoro-Phenyl)-1H-Quinoline-2,4-Dione (KR22332) Exerts a Radioprotective Effect via the Inhibition of Mitochondrial Dysfunction and Generation of Reactive Oxygen Species

Baek SJ, Chang JW, Park KH, Yang GY, Hwang HS, Koh YW, Jung YS, Kim CH

PURPOSE: Acute side effects of radiation such as oral mucositis are observed in most patients. Although several potential radioprotective agents have been proposed, no effective agent has yet been identified....
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Protective effect of 4,4'-diaminodiphenylsulfone against paraquat-induced mouse lung injury

Cho SC, Rhim JH, Choi HR, Son YH, Lee SJ, Song KY, Park SC

Although 4,4'-diaminodiphenylsulfone (DDS, dapsone) has been used to treat several dermatologic conditions, including Hansen disease, for the past several decades, its mode of action has remained a topic of debate....
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Protective Role of Purified Cysteine Proteinases against Fasciola gigantica Infection in Experimental Animals

EL-Ahwany , Rabia I, Nagy F, Zoheiry M, Diab T, Zada S

Fascioliasis is one of the public health problems in the world. Cysteine proteinases (CP) released by Fasciola gigantica play a key role in parasite feeding, migration through host tissues, and...
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Effect-Site Concentration of Remifentanil for Minimizing Cardiovascular Changes by Inhalation of Desflurane

Jeong HJ, Baik HJ, Kim JH, Kim YJ, Bahk JH

PURPOSE: This study aims to investigate the most appropriate effect-site concentration of remifentanil to minimize cardiovascular changes during inhalation of high concentration desflurane. MATERIALS AND METHODS: Sixty-nine American Society of Anesthesiologists...
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Protective Effect of Sauchinone Against Regional Myocardial Ischemia/Reperfusion Injury: Inhibition of p38 MAPK and JNK Death Signaling Pathways

Kim SJ, Jeong CW, Bae HB, Kwak SH, Son JK, Seo CS, Lee HJ, Lee J, Yoo KY

Sauchinone has been known to have anti-inflammatory and antioxidant effects. We determined whether sauchinone is beneficial in regional myocardial ischemia/reperfusion (I/R) injury. Rats were subjected to 20 min occlusion of...
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