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Cyclooxygenase and Prostaglandin in Cancer

Kim JW

No abstract available.
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Targeting Cyclooxygenase 2 and HER - 2 / neu Pathways Inhibits Colorectal Carcinoma Growth

Kim YS, Kim YB, Chun HJ

  • KMID: 2085000
  • Korean J Gastroenterol.
  • 2001 Aug;38(2):144-145.
No abstract available.
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The role of cyclooxygenase metabolities in the pathogeneticmechanism of endotoxin-induced acute lung injury in domestic pigs

Yoo CG, Jeong KH, Choi HS, Lee HP, Kim YW, Han SK, Shim YS, Kim KY, Han YC

  • KMID: 1699802
  • Tuberc Respir Dis.
  • 1992 Feb;39(1):42-54.
No abstract available.
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The Effects of Lipoxygenase and Cyclooxygenase Inhibitors to Meningioma Cell Proliferation in vitro

Park YS, Koo TH, Lee JH, Lee YB, Lee KC, Mok JH, Kim HS

  • KMID: 1546426
  • J Korean Neurosurg Soc.
  • 2000 Jan;29(1):28-34.
No abstract available.
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Alteration in Contact Hypersensitivity of Mice induced by Indomethacin Treatment

Hann SK, Park YK, Kim HI, Choi EH

  • KMID: 2231250
  • Korean J Dermatol.
  • 1990 Jun;28(3):278-282.
To study the effect of indomethacin treatment on the reactivity of contact hypersensitivity and discuss relevant mediators which could affect contact hypersensitivity, the following items were evaluated: the change in...
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Treatment of PDA in premature newborns with mefenamic acid

Lee JJ, Lee YH, Shin SM

  • KMID: 2320418
  • Yeungnam Univ J Med.
  • 1993 Dec;10(2):506-511.
This study was conducted to examine the effect of mefenamic acid for treatment of PDA in premature newborns. Ductus arteriosus is reopened by locally produced prostaglandin E2 in a premature...
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The Effect of Indomethacin on Biphasic Intraocular Pressure Response to Laser Irradiaion of the Iris

Kim YY

  • KMID: 2336754
  • J Korean Ophthalmol Soc.
  • 1999 Jan;40(1):192-196.
Laser irradiation of the iris can induce acute increase in intraocular pressure (IOP) as well as hypotony. the author evaluated the effect of the prostaglandin on the biphasic IOP response....
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Colorectal Cancer and Prostaglandin

Chang WK

  • KMID: 1626393
  • J Korean Soc Coloproctol.
  • 2003 Feb;19(1):52-59.
The possibility for cyclooxygenase (COX) inhibitors in colorectal cancer prevention and theraphy is evident from epidemiologic data (reduction of colorectal cancer in nonsteroidal anti-inflammatory drugs (NSAIDs) users), animal experiments (nude...
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Hyponatremia and Generalized Edema Associated with Ibuprofen Therapy in a Neonate

Kim SH, Kim EY, Park SK

  • KMID: 2188595
  • J Korean Soc Neonatol.
  • 2006 May;13(1):176-179.
Ibuprofen is a nonsteroidal anti-inflammatory, analgesic, and antipyretic agent which has used for the treatment of rheumatoid and musculoskeletal disorders. Its side effects have generally been minor; these include dyspepsia,...
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New COX-2 Inhibitors

Kim D, Sung YK

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain and inflammation. There are two kinds of NSAID classified according to the selectivity of COX-2 inhibition: non-selective NSAIDs and cyclooxygenase...
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Physiology and pathophysiology of cyclooxygenase-2 and prostaglandin E2 in the kidney

Norregaard R, Kwon TH, Frokiaer J

The cyclooxygenase (COX) enzyme system is the major pathway catalyzing the conversion of arachidonic acid into prostaglandins (PGs). PGs are lipid mediators implicated in a variety of physiological and pathophysiological...
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Chemoprevention of Gastric Cancer: Non-steroidal Anti-inflammatory Drugs Including Aspirin

Choi KD

Many reports have been published that provide epidemiological evidence supporting the efficacy of aspirin and non-steroidal anti- inflammatory drugs (NSAIDs) in cancer prevention. The presumed mechanism of chemoprevention is inhibition...
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A case of acetaminophen induced bronchial asthma without aspirin sensitivity

Kim SS, Lee SK, Nahm DH, Park HS

  • KMID: 2285986
  • J Asthma Allergy Clin Immunol.
  • 2000 Jun;20(3):545-550.
Acetaminophen is a widely used analgesic-antipyretic. Hypersensitivity reactions to acetaminophen are rare and selective sensitivity to acetaminophen without aspirin or non-steroidal antiinflammatory drug intolerance is even rarer. We experienced a...
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Inhibition of the Apraclonidine induced Reduction of Intraocular Presure by Topical Suprofen in Normal Human Eyes

Kim CI, Kim HM, Jung HR

  • KMID: 2122976
  • J Korean Ophthalmol Soc.
  • 1991 Jan;32(1):74-77.
We studied the effect of prostaglandin synthesis inhibitor on the ocular hypotensive action of apraclonidine in a prospective, double-masked study. Twenty normal volunteers were studied. Suprofen, cyclooxygenase;nhibitor and apraclonidine were...
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Increased Expression of Prostaglandin H synthase by Aspirin in Cultured Cells from Amnionic Cell Line WISH Cells

Cha MS, Kwak JY

  • KMID: 2026745
  • Korean J Obstet Gynecol.
  • 1998 Nov;41(11):2821-2826.
Prostaglandins which are produced from amnionic cells are known to play a major role in uterine contraction and cervical dilatation in human. Recently it is reported that aspirin increases the...
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Contact Urticaria: Etiology and Blocking Effect of Some Drugs

Yang JM

  • KMID: 2231513
  • Korean J Dermatol.
  • 1986 Dec;24(6):766-770.
This study was undertaken to investigate the response of nonimmunologic contact urticaria(NICU) test before and after ingestion of cimetidine, homoclorcyclizine and indomethacin. Thirty-five patients who showed positive reaction to 5%...
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Two cases of anaphylaxis to diclofenac with aspirin tolerance

Lee JY, Byun YH, Cho YB, Lee BH, Ahn Y, Kim SH

  • KMID: 1984652
  • Korean J Med.
  • 2005 Jul;69(1):113-116.
Anaphylaxis is an acute life-threatening reaction, usually mediated by immunologic and non- immunologic mechanisms. Non-steroidal anti-inflammatory drugs (NSAIDs) can produce anaphylactic reactions by different pathogenic mechanisms. The most of these...
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The Role of Prostaglandins in Surgically Induced Miosis

Lee KW, Lee SS

  • KMID: 2022994
  • J Korean Ophthalmol Soc.
  • 1991 Nov;32(11):964-969.
In cataract surgery, the surgically induced miosis complicate the removal of lens materials and implantation of a posterior chamber intraocular lens, which increase the risk of ocular trauma and its...
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The Role of Neutrophil on Nonsteroidal Anti-Inflammatory Drugs Induced Acute Gastric Mucosal Injury

Yun BY, Kim JH, Lee HJ, Jang BI, Kim TN, Chung MK, Choi JH

  • KMID: 1571054
  • Korean J Gastroenterol.
  • 2000 Feb;35(2):154-162.
BACKGROUND/AIMS: Gastric mucosal injury caused by nonsteroidal anti-inflammatory drugs (NSAIDs) is one of the most frequent adverse reactions. However, the precise mechanism of such injury remains still unclear. The present study was...
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Molecular Targeted Therapy in Colorectal Cancer

Yun SH

  • KMID: 1835450
  • J Korean Soc Coloproctol.
  • 2004 Jun;20(3):180-188.
In the last few years, the knowledge of molecular oncology has led to the development of many new biological agents whose targets are extracellular or intracellular molecules involved in the...
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