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The Need for Actions Against Polypharmacy in Older People With Frailty

Kojima T

Providing safe and effective drug therapy to older patients is challenging for physicians since there is not sufficient evidence to support the efficacy of these drugs and this population is...
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Treatment Principles of Atiepileptic Drug Therapy and Rational Polypharmacy Including new antiepileptic Drugs

Kim YC

  • KMID: 2137183
  • J Korean Child Neurol Soc.
  • 2001 May;9(1):228-238.
No abstract available.
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Recent Trends of Antipsychotics Polypharmacy in Schizophrenia

Chang JG, Roh D, Kim CH

  • KMID: 2287447
  • Korean J Psychopharmacol.
  • 2013 Oct;24(4):137-146.
Antipsychotics polypharmacy is a common practice in clinical settings despite the opposition of most guidelines for treatment of schizophrenia. This article reviews the evidence of antipsychotics polypharmacy and summarizes advantages...
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Risk Factors of Potentially Inappropriate Medications and Cost by Polypharmacy among Elderly Patients of a Community Pharmacy near a Top Tier General Hospital

Kim A, Kim HA, Rhie SJ

OBJECTIVE: Polypharmacy is one of the main causes of inappropriate medication use, adverse drug-related events and cost. It aimed to investigate the status of polypharmacy and potentially inappropriate medication (PIM),...
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Factors Associated with Drug Misuse Behaviors among Polypharmacy Elderly

Lee JK

  • KMID: 2298353
  • Korean J Adult Nurs.
  • 2011 Dec;23(6):554-563.
PURPOSE: The purpose of this study was to investigate factors associated with drug misuse behaviors among polypharmacy elderly. METHODS: This was a cross-sectional survey. Participants consisted of 116 polypharmacy elderly who...
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Polypharmacy is a risk factor for disease flare in adult patients with ulcerative colitis: a retrospective cohort study

Wang J, Nakamura T, Tuskey AG, Behm BW

BACKGROUND/AIMS: Polypharmacy is a common clinical problem with chronic diseases that can be associated with adverse patient outcomes. The present study aimed to determine the prevalence and patient-specific characteristics associated...
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Antipsychotic Polypharmacy in the Treatment of Patients with Related Psychoses at a University Hospital

Chang JG, Roh D, An SK, Cho HS, Kim CH

  • KMID: 2287455
  • Korean J Psychopharmacol.
  • 2013 Apr;24(2):69-75.
OBJECTIVE: The practice of antipsychotic polypharmacy is common, despite lack of supporting evidence. The aims of this study were to estimate the prevalence of antipsychotic polypharmacy in a psychiatric university...
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Antipsychotics Prescribing Patterns of Patients with Schizophrenia Admitted to Korean General Hospital Psychiatric Unit: 2001 to 2008

Choi HJ, Jung SH, Kang MH, Lee JS, Bae JN, Kim CE

  • KMID: 2171281
  • Clin Psychopharmacol Neurosci.
  • 2011 Apr;9(1):17-22.
OBJECTIVE: Although the standard of treatment for schizophrenia is antipsychotic monotherapy, overall psychotropic polypharmacy including antipsychotic polypharmacy is increasingly practiced by clinicians. However, there are very few studies that assess...
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Prescription Patterns for Patients with Schizophrenia in Korea: A Focus on Antipsychotic Polypharmacy

Kim HY, Lee HW, Jung SH, Kang MH, Bae JN, Lee JS, Kim CE

  • KMID: 2279944
  • Clin Psychopharmacol Neurosci.
  • 2014 Aug;12(2):128-136.
OBJECTIVE: This study investigated the prescription patterns for Korean patients with schizophrenia with a particular focus on antipsychotic polypharmacy. All data were gathered from patients presenting at 41 tertiary university...
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The Influence of Previous Antipsychotic Polypharmacy Versus Monotherapy on the Effectiveness of Antipsychotic after Switching to Paliperidone Extended-release

Lee HW, Na KS, Jung SH, Kang MH, Lee JS, Bae JN, Kim HY, Kim CE

  • KMID: 2171149
  • Clin Psychopharmacol Neurosci.
  • 2013 Dec;11(3):152-157.
OBJECTIVE: Although antipsychotic polypharmacy is widely used in the pharmacotherapy of schizophrenia, its effectiveness is controversial. In particular, clinicians tend to avoid switching to monotherapy in patients who have been...
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A Study on Polypharmacy in the Elderly Psychiatric Outpatients with Persistent Treatments for 3 years

Yoo HS, Jung IK

  • KMID: 1462768
  • J Korean Geriatr Psychiatry.
  • 2010 Jun;14(1):50-57.
OBJECTIVES: The objective of this study was to investigate the prescription trends for the elderly psychiatric outpatients at a university hospital. METHODS: We performed a retrospective study based on medical records....
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Medications as Risk Factor for Falls

Lee YW, Nam SI

Falls are the most common cause of accidents among the older population, leading to both fatal and non-fatal injuries. Falls is a syndrome resulting from the cumulative effect of various...
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Patterns of Drug Use and Factors Associated with Polypharmacy in Elderly Patients Visiting Psychiatric Outpatient Clinic

Jung YK, Lee KJ, Kim H

  • KMID: 2342329
  • J Korean Neuropsychiatr Assoc.
  • 2012 Sep;51(5):312-317.
OBJECTIVES: The objective of this study was to investigate the patterns and recent trends in polypharmacy among elderly patients visiting psychiatric outpatient clinic. METHODS: 289 elderly patients visiting psychiatric outpatient clinic...
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Evaluation and management of frailty

Won CW

Physical frailty is a state in which the functional capacity of various organs in the body drops below a certain level, making an individual vulnerable to a variety of stresses;...
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Examining Patterns of Polypharmacy in Bipolar Disorder: Findings from the REAP-BD, Korea

Kim K, Yang H, Na E, Lee H, Jang OJ, Yoon HJ, Oh HS, Ham BJ, Park SC, Lin SK, Tan CH, Shinfuku N, Park YC

Based on Korean data from the Research on Asian Psychotropic Prescription Pattern for Bipolar Disorder, this study tried to present prescription patterns in biopolar disorder (BD) and its associated clinical...
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Prescribing Pattern of Clozapine and Clinical Factors associated with Discontinuation of Clozapine

Kang SH, Lee HW

OBJECTIVES: Clozapine is the drug of choice in treatment-resistant schizophrenia. However, its use is often delayed and a significant proportion of clozapine treated patients fails to respond and experience potentially...
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Use of Antiepileptic Drugs in the Elderly

Kwon OY

  • KMID: 1480897
  • J Korean Epilepsy Soc.
  • 2008 Dec;12(2):67-77.
The incidence of epilepsies and seizures is higher in the age group over 65-year-old than any other age group. The reduction of the dosages of antiepileptic drugs is recommended and...
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Risk Factors Associated with the Severity of Delirium

Seo YE, Kim TS, Won WY, Lee CU, Lee C

  • KMID: 2341825
  • J Korean Neuropsychiatr Assoc.
  • 2010 Nov;49(6):586-592.
OBJECTIVES: The purpose of this study was to investigate the relationship between the sum of the risk factors for delirium and the severity of delirium and to identify those risk...
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Management of multimorbidity in the ederly

Kim SW, Kim KI

As the population ages, more people are living with multiple medical conditions, and patients are suffering from functional decline or disabilities as part of multimorbidity. Multiple chronic diseases are the...
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Polypharmacy in Older Patients Admitted to a General Hospital

Seo DS, Yoon JL, Kim SJ, Park JS, Lee WJ, Kim MY

  • KMID: 2339435
  • J Korean Geriatr Soc.
  • 2012 Sep;16(3):133-140.
BACKGROUND: The elderly population is rapidly growing in numbers in Korea. According to the high prevalence of chronic disease in older persons, the issue of polypharmacy becomes one of the...
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