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Effects of Interleukin-13 and Montelukast on the Expression of Zonula Occludens-1 in Human Podocytes

Park SJ, Saleem MA, Nam JA, Ha TS, Shin JI

PURPOSE: The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and...
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The reno-protective effect of a phosphoinositide 3-kinase inhibitor wortmannin on streptozotocin-induced proteinuric renal disease rats

Kim SH, Jang YW, Hwang P, Kim HJ, Han GY, Kim CW

Diabetic nephropathy (DN) is a progressive kidney disease that is caused by injury to kidney glomeruli. Podocytes are glomerular epithelial cells and play critical roles in the glomerular filtration barrier....
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