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Post-traumatic Intramuscular Hemangioma of the Chest Wall

Ryu KM, Lee WA

Intramuscular hemangioma originated in chest wall is a rare benign tumor, with no relevant reports in Korea. In most cases, the tumor is discovered before the age of 30 years...
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Sarcopenia: Ammonia metabolism and hepatic encephalopathy

Jindal A, Jagdish RK

Sarcopenia (loss of muscle mass and/or strength) frequently complicates liver cirrhosis and adversely affects the quality of life; cirrhosis related liver decompensation and significantly decreases wait-list and post-liver transplantation survival....
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Proteomic Analysis of Hepatic Ischemia and Reperfusion Injury in Mice

Cho EH, Sung JH, Koh PO

Hepatic ischemia/reperfusion (I/R) injury is an inevitable consequence during liver surgery. I/R injury induces serious hepatic dysfunction and failure. In this study, we identified proteins that were differentially expressed between...
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RNA Granules and Stress Granules in Virus Systems

Kim K

Viruses initiate a number of cellular stress responses and modulate gene regulation and compartmentalization of RNA upon infection to be successful parasites. Virus infections may induce or impair stress granule...
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Preliminary Report of Short-Term Proteomic Changes following Bilateral Oophorectomy in the Female Rat Bladder Tissue

Kim HJ, Jeong H, Ryu YG

  • KMID: 2330534
  • J Korean Continence Soc.
  • 2006 Dec;10(2):121-125.
PURPOSE: The pathophysiological mechanisms of the bladder dysfunction in postmenopausal state are not well understood especially in moleclular level. Therefore we investigated the changes of bladder in female rat following...
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Differential gene expression pattern in brains of acrylamide-administered mice

Han CH

  • KMID: 1435820
  • Korean J Vet Res.
  • 2012 Jun;52(2):99-104.
The present study was performed to evaluate the relationship between the neurotoxicity of acrylamide and the differential gene expression pattern in mice. Both locomotor test and rota-rod test showed that...
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Non-negligible Occurrence of Errors in Gender Description in Public Data Sets

Kim JH, Park JL, Kim SY

Due to advances in omics technologies, numerous genome-wide studies on human samples have been published, and most of the omics data with the associated clinical information are available in public...
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Proteomic Changes in the Female Rat Bladder Tissue following Bilateral Oophorectomy

Lee HC, Kim HJ

  • KMID: 2331554
  • J Korean Continence Soc.
  • 2009 Dec;13(2):134-141.
PURPOSE: To explore the effect of bilateral oophorectomy on the several proteins of female rat bladder via a proteomic approach. MATERIALS AND METHODS: A total of 20 female Sprague-Dawley rats were...
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Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model

Ayyappan J, lizardo K, Wang S, Yurkow E, Nagajyothi JF

Trypanosoma cruzi infection results in debilitating cardiomyopathy, which is a major cause of mortality and morbidity in the endemic regions of Chagas disease (CD). The pathogenesis of Chagasic cardiomyopathy (CCM)...
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Inhibition of Mast Cell Function and Proliferation by mTOR Activator MHY1485

Rakhmanova V, Jin M, Shin J

Mast cells integrate innate and adaptive immunity and are implicated in pathophysiological conditions, including allergy, asthma, and anaphylaxis. Cross-linking of the high-affinity IgE receptor (FcεRI) initiates diverse signal transduction pathways...
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4-phenylbutyric Acid Regulates Collagen Synthesis and Secretion Induced by High Concentrations of Glucose in Human Gingival Fibroblasts

Lee GH, Oh HW, Lim HD, Lee W, Chae HJ, Kim HR

High glucose leads to physio/pathological alterations in diabetes patients. We investigated collagen production in human gingival cells that were cultured in high concentrations of glucose. Collagen synthesis and secretion were...
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The Effects of Glyburide on Apoptosis and Endoplasmic Reticulum Stress in INS-1 Cells in a Glucolipotoxic Condition

Kwon MJ, Chung HS, Yoon CS, Ko JH, Jun HJ, Kim TK, Lee SH, Ko KS, Rhee BD, Kim MK, Park JH

BACKGROUND: beta-cell death due to endoplasmic reticulum (ER) stress has been regarded as an important pathogenic component of type 2 diabetes. The possibility has been suggested that sulfonylurea, currently being...
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Guanabenz Acetate Induces Endoplasmic Reticulum Stress–Related Cell Death in Hepatocellular Carcinoma Cells

Kang HJ, Seol HS, Lee SE, Suh YA, Kim J, Jang SJ, Yu E

BACKGROUND: Development of chemotherapeutics for the treatment of advanced hepatocellular carcinoma (HCC) has been lagging. Screening of candidate therapeutic agents by using patient-derived preclinical models may facilitate drug discovery for...
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A Catalogue of Gene Expression Difference in Biliary Cirrhosis due to Biliary Atresia Using Differential Expressed Sequence Tags(EST) Screening

Choe BH, Lee HM, Kim MK, Kim JC

  • KMID: 1946275
  • J Korean Pediatr Soc.
  • 2000 Jan;43(1):60-69.
PURPOSE: Extrahepatic biliary atresia is the most common indication for liver transplantation in children, but the etiology of this disorders remains unknown. It would be very signficant to identify genes...
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Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells

Hong SW, Lee J, Cho JH, Kwon H, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY

BACKGROUND: The nuclear receptor peroxisome proliferator-activator gamma (PPARγ) is a useful therapeutic target for obesity and diabetes, but its role in protecting β-cell function and viability is unclear. METHODS: To identify...
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