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The Role of Proteinases in Tumor Invasion and Metastasis

Lim YT

  • KMID: 2335263
  • J Korean Pediatr Soc.
  • 1997 Jul;40(7):901-907.
No abstract available.
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Acute Pancreatitis with Purtscher's-like Retinopathy

Han JS, Nam SE, Jang DK, Lee JK

A 28-year-old man with a history of alcohol abuse was diagnosed with acute pancreatitis based on clinical symptoms, laboratory findings and computed tomography findings. On the second day of hospitalization,...
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Pathophysiology of Chronic Obstructive Pulmonary Disease

Lee SD

Chronic obstructive pulmonary disease (COPD) is a chronic progressive disease that is characterized by irreversible airflow limitation with a partially reversible component. The pathologic abnormalities of COPD are associated with...
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Herpesvirus-encoded Deubiquitinating Proteases and Their Roles in Regulating Immune Signaling Pathways

Kwon KM, Ahn JH

Viruses interact with the host ubiquitination system in a variety of ways. Viral proteins are often a substrate for ubiquitination, which leads to proteasomal degradation. Viruses also have functions to...
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Optimization of Protein Extraction for Lichen Thalli

Kondratiuk AS, Savchuk OM, Hur JS

Lichen-forming fungal proteins have been seldom searched due to many difficulties in their extraction. Phenols, quinones, proteases, and other components released during cell disruption have been known to be the...
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Hyponatremia in schizophrenia after water intoxification: a potential cause of rhabdomyolysis

Jun DW, Kim SH, Kim KH, Jang WY, Na KS, Kim HJ

  • KMID: 2080783
  • Korean J Med.
  • 2000 Sep;59(3):335-338.
Electrolyte disturbance that can produce rhabdomyolysis include hyperosmolar states, especially with marked hyperglycemia, or hypernatremia, severe hypokalemia, and hypophosphatemia, which is commonly seen in alcholics. Hyponatremia, however, is often an...
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Effects of RGD Protein on the Bone Resorptive Activity of Osteoclast

Chang JS, Kim KY, Kim YT, Lee CS, Han BH, Hong SW

  • KMID: 2190008
  • J Korean Orthop Assoc.
  • 1997 Apr;32(2):457-463.
Osteoclasts resorb bone by the hydrogen ions and proteolytic enzymes in the localize environment under the ruffled border. Before releasing hydrogen ion and enzymes, osteoclast should attach to bone surface...
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Atopic Dermatitis and Epidermal Barrier

Lee HH

  • KMID: 2314937
  • Pediatr Allergy Respir Dis.
  • 2009 Jun;19(2):95-105.
Atopic dermatitis (AD) is a multifactorial, chronic inflammatory skin disease in which genetic mutations and cutaneous hyperreactivity to environment stimuli play a role. The skin barrier is known to be...
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Matrix Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-1 levels in Exudative Pleural Effusions

Cho JH, Nam JH, Lee KH, Yoon BK, Ryu JS, Kwak SM, Lee HL

  • KMID: 2318695
  • Tuberc Respir Dis.
  • 2005 Nov;59(5):517-521.
BACKGROUND: The balances of the proteinases and antiproteinases system have been implicated in the pathogenesis of various exudative pleural effusions. The aim of this study was to examine the matrix...
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Potential role(s) of cysteine cathepsins in cancer progression and metastasis

Lee HR, Choi KC

  • KMID: 2055088
  • J Biomed Res.
  • 2013 Mar;14(1):1-7.
Cancer is the result of damage to the genetic system, i.e., dysfunction of the DNA repair system, resulting in dysregulated expression of various molecules, leading to cancer formation, migration, and...
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Partial Purification and Characterization of 41 kDa Serine Proteinase from Culture Filtrate of Trichophyton tonsurans

Yoo JI, Lee YS, Choi YH, Joo HY, Kim BS, Suh SB

  • KMID: 2146911
  • J Korean Soc Microbiol.
  • 1999 Jun;34(3):303-310.
Dermatophytes infect the human hair, skin, nail and cause the dermatophytosis. The extracellular and intracellular proteinases of the dermatophytes commonly occur in the genus Trichophyton like T. rubrum, T. mentagrophytes,...
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Characterization of proteases isolated from Kudoa septempunctata

Shin SP, Zenke K, Yokoyama H

Proteases play important roles in parasite development and host parasite interactions. The protease of Kudoa spp. has been recognized as a key factor of severe proteolysis of fish muscle post-mortem;...
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A Case of Thrombosis of the Inferior Vena Cava and Right Iliac Vein Complicated by Chronic Pancreatitis

Lee SW, Kim YS, Moon JH, Cho YD, Lee MS, Shim CS

  • KMID: 1929450
  • Korean J Gastrointest Endosc.
  • 2000 Feb;20(2):158-162.
Vascular thrombosis and systemic hypercoagulable states are known complications of pancreatitits. The incidence of vascular obstruction associated with pancreatitis has been reported at 0.9%. They are thought to be secondary...
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Atopic dermatitis and skin barrier dysfunction

Kim H, Shin JU, Lee KH

Atopic dermatitis is a chronic relapsing eczematous dermatosis, which usually starts in childhood, and various causes are intricately associated with the development of the disease. Recently, various abnormalities in barrier...
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Effects of Epigallocatechin Gallate on Adhesion, Invasion and Matrix Metalloproteinase Activity in MDA-MB-231 Human Breast Cancer Cells

Bang MH, Kim JH, Kim WK

  • KMID: 2269820
  • Korean J Nutr.
  • 2005 Mar;38(2):104-111.
Tumor invasion is composed of four steps: cell adhesion to the extracellular matrix, degradation of the extracellular matrix components, tumor cell motility followed by cell detachment. Matrix metalloproteinases (MMPs) are...
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Antagonistic Evaluation of Chromobacterium sp. JH7 for Biological Control of Ginseng Root Rot Caused by Cylindrocarpon destructans

Han JH, Park GC, Kim KS

Cylindrocarpon destructans is an ascomycete soil-borne pathogen that causes ginseng root rot. To identify effective biocontrol agents, we isolated several bacteria from ginseng cultivation soil and evaluated their antifungal activity....
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Caspase 3 and Ki-67 Immunoreactivity and Its Correlation with Frequency of Apoptosis in Gastric Adenomas and Carcinomas

Sohn JH, Chae SW, Choi KC, Shin HS

  • KMID: 1725815
  • Korean J Pathol.
  • 2001 Aug;35(4):286-290.
BACKGROUND: Apoptosis, also known as programmed cell death, is under genetic control and is mediated by apoptosis-specific genes, certain oncogenes and tumor suppressor genes. Caspase 3, a group of cystein...
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The Study of K Channels in Smooth Muscle Cells of Rabbit Seminal Vesicle

Yang KS, Lee JS, Han SH, Lee MY

  • KMID: 2298728
  • Korean J Androl.
  • 2009 Dec;27(3):177-184.
PURPOSE: Ionic currents in smooth muscle have fundamental roles in initiation and maintenance of excitability and contractile status. So we studied and characterized potassium ion channels in smooth muscle cells...
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The Study of the Cytotoxic Mechanism of Cisplatin in HeLa Cells

Choi JH, Cho H, Lee SY, Oh SH, Kim HG, Park RG

  • KMID: 2076939
  • Korean J Obstet Gynecol.
  • 2003 Oct;46(10):1989-1998.
Cis-diamminedichloroplatinum II (cisplatin) has been reported to induce cell death. However, the mechanism by which cisplatin is induced the apoptosis of cancer cells is still unclear. To evaluate the mechanistic...
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iRhoms; Its Functions and Essential Roles

Lee MY, Nam KH, Choi KC

In Drosophila, rhomboid proteases are active cardinal regulators of epidermal growth factor receptor (EGFR) signaling pathway. iRhom1 and iRhom2, which are inactive homologs of rhomboid intramembrane serine proteases, are lacking...
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