- Function of the pentose phosphate pathway and its key enzyme, transketolase, in the regulation of the meiotic cell cycle in oocytes
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Kim Y, Kim EY, Seo YM, Yoon TK, Lee WS, Lee KA
- KMID: 1743692
- Clin Exp Reprod Med.
- 2012 Jun;39(2):58-67.
- doi: 10.5653/cerm.2012.39.2.58
OBJECTIVE: Previously, we identified that transketolase (Tkt), an important enzyme in the pentose phosphate pathway, is highly expressed at 2 hours of spontaneous maturation in oocytes. Therefore, this study was... -
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- The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy
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Cho ES, Cha YH, Kim HS, Kim NH, Yook JI
- KMID: 2400812
- Biomol Ther.
- 2018 Jan;26(1):29-38.
- doi: 10.4062/biomolther.2017.179
During cancer progression, cancer cells are repeatedly exposed to metabolic stress conditions in a resource-limited environment which they must escape. Increasing evidence indicates the importance of nicotinamide adenine dinucleotide phosphate... -
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- In Silico Identification of 6-Phosphogluconolactonase Genes that are Frequently Missing from Completely Sequenced Bacterial Genomes
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Jeong H, Kim JF, Park HS
- KMID: 2166245
- Genomics Inform.
- 2006 Dec;4(4):182-187.
6-Phosphogluconolactonase (6PGL) is one of the key enzymes in the ubiquitous pathways of central carbon metabolism, but bacterial 6PGL had been long known as a missing enzyme even after complete bacterial... -
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- Species-specific Expression of Rpia Transcript in Cumulus-oocyte-complex
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Kim YS, Yoon SJ, Kim EY, Lee KA
- KMID: 2288276
- Korean J Reprod Med.
- 2007 Jun;34(2):95-106.
OBJECTIVE: We previously identified differentially expressed genes (DEGs) between germinal vesicle (GV) and metaphase II (MII) mouse oocyte.(1) The present study was accomplished as a preliminary study to elucidate the... -
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- Protective Mechanism of Glucose against Alloxan-Indeved HIT-T15 Cell Damage
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Lee TH, Park TS, Kim HR
- KMID: 2177941
- J Korean Diabetes Assoc.
- 1999 Aug;23(4):530-540.
BACKGROUND: Glucose prevents the development of alloxan-induced diabetes, but the precise protective mechanism of glucose is not yet clearly known. METHODS: The protective mechanism of glucose on alloxan-induced B-cell damage... -
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- My Sweetheart Is Broken: Role of Glucose in Diabetic Cardiomyopathy
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Brahma MK, Pepin ME, Wende AR
- KMID: 2368523
- Diabetes Metab J.
- 2017 Feb;41(1):1-9.
- doi: 10.4093/dmj.2017.41.1.1
Despite overall reductions in heart disease prevalence, the risk of developing heart failure has remained 2-fold greater among people with diabetes. Growing evidence has supported that fluctuations in glucose level... -
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- Glucose-6-phosphate dehydrogenase deficiency does not increase the susceptibility of sperm to oxidative stress induced by Hâ‚‚Oâ‚‚
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Roshankhah S, Rostami-Far Z, Shaveisi-Zadeh F, Movafagh A, Bakhtiari , Shaveisi-Zadeh J
- KMID: 2364655
- Clin Exp Reprod Med.
- 2016 Dec;43(4):193-198.
- doi: 10.5653/cerm.2016.43.4.193
OBJECTIVE: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect. G6PD plays a key role in the pentose phosphate pathway, which is a major source of nicotinamide adenine... -
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- Obesity-Associated Metabolic Signatures Correlate to Clinical and Inflammatory Profiles of Asthma: A Pilot Study
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Liu Y, Zheng J, Zhang HP, Zhang X, Wang L, Wood L, Wang G
- KMID: 2441813
- Allergy Asthma Immunol Res.
- 2018 Nov;10(6):628-647.
- doi: 10.4168/aair.2018.10.6.628
PURPOSE: Obesity is associated with metabolic dysregulation, but the underlying metabolic signatures involving clinical and inflammatory profiles of obese asthma are largely unexplored. We aimed at identifying the metabolic signatures... -
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