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Oxidation-reduction potential as a new marker for oxidative stress: Correlation to male infertility

Agarwal A, Bui AD

Male infertility affects men worldwide. Oxidative stress (OS), characterized by an overabundance of reactive oxygen species (ROS) or a deficiency of antioxidants, is one of the major causes of male...
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Characterization of Binding and Phagocytosis of Oxidatively Damaged Erythrocyte to Macrophage

Ko HS, Kim IS, Lee KJ, Kim SW, Kim CJ, Ryu WS

  • KMID: 759614
  • Korean J Intern Med.
  • 2002 Dec;17(4):220-226.
BACKGROUND: Scavenger receptors are thought to be involved in the recognition of oxidized low-density lipoprotein (oxLDL) and oxidized erythrocyte (oxRBC). However, there are controversies about the kind of receptors...
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Oxidation-dependent effects of oxidized LDL: proliferation or cell death

Han CY, Kim Pak YM

  • KMID: 1029922
  • Exp Mol Med.
  • 1999 Dec;31(4):165-173.
Oxidized low-density lipoprotein (oxLDL) induces a wide range of cellular responses to produce atherosclerotic lesion, but key factors determining the response are not understood. In this study, purified...
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Activation domain in P67phox regulates the steady state reduction of FAD in gp91phox

Han CH, Lee MH

  • KMID: 1103471
  • J Vet Sci.
  • 2000 Jun;1(1):27-31.
An activation domain in p67(phox) (residues 199-210) is critical for regulating NADPH oxidase activity in cell-free system [10] To determine the steady state reduction of FAD, thioacetamide-FAD was reconstituted in...
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Enhancement of O-dealkylation in Mouse Liver by Dietary Administrations of BHA and BHT: Studies with Isolated Perfused Livers and Hepatic Microsomes

Ji SC, Conway JG, Thurman RG, Cha YN

Effects of feeding 2(3)-tert-butyl 4-hydroxyanisole (BHA) and 3, 5-di-tert-butyl 4-hydroxytoluene (BHT) on the rates of mixed function oxidation and conjugation enzyme reactions have been determined using isolated hepatic microsomal fractions...
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Autophagy in Redox Signalling

Choi TG, Kim SS

Autophagy is a major catabolic process that is involved in cellular degradation of unnecessary or dysfunctional cellular components via the lysosomal machinery. Autophagy is involved in a variety of biological...
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Antimicrobial effect of slightly acidic electrolyzed water on oral microorganisms

Park YK

  • KMID: 2321421
  • J Korean Acad Oral Health.
  • 2013 Dec;37(4):187-193.
OBJECTIVES: The purpose of this study was to evaluate the antibacterial effect of slightly acidic electrolyzed water (SAEW) for use as a mouth-rinse on seven oral pathogens. METHODS: In this study,...
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The Effect of Cytochrome C in Ophthalmic Diseases

Kim HC, Kim JJ, Pak BG

  • KMID: 1675861
  • J Korean Ophthalmol Soc.
  • 1968 Mar;9(1):1-8.
Cytochrome compounds which act as electron transfer agents in oxidation-reduction reactions. An important example is cytochrome c, which has a molecular weight of about 13,000 and contains one atom of...
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Hypoxic Pulmonary Vasoconstriction and Change in Outward K Current in Pulmonary Arterial Smooth Muscle Cell of the Rabbit

Song DK, Park MK

  • KMID: 1546021
  • Korean J Aerosp Environ Med.
  • 1999 Jun;9(2):171-175.
Hypoxic pulmonary vasoconstriction (HPV) is well-known characteristic of pulmonary artery during the exposure of low O2 conditions. It has been demonstrated that hypoxia inhibits an outward K current, thus causing...
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A Study of Oxidative Stress Parameters in Anti-Helicobacter Pylorus Immunoglobulin G Positive and Negative Gastric Cancer Patients

Noyan T, Guducuoglu H, Ilhan M

PURPOSE: Helicobacter pylorus (HP) is a Gram-negative spiral-shaped microaerophilic bacterium, which colonizes in the gastric mucosa of humans. The gastric human pathogen HP causes chronic gastritis and ulcers, and has...
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Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein

Choi S, Joo HK, Jeon BH

Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multifunctional protein that plays a central role in the cellular response to DNA damage and redox regulation against oxidative stress. APE1/Ref-1 functions in...
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Wear of Retrieved UHMWPE Hip Liners

Lee KY, Kim SY, Shin DH, Lee SJ, Kim SY

  • KMID: 2428326
  • Yonsei Med J.
  • 2004 Apr;45(2):293-299.
After the gamma-irradiation sterilization, the most widely used orthopaedic grade polymer bearing liner material for the total joint replacement, ultra-high molecular weight polyethylene (UHMWPE), degrades through the progressive in vivo...
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Studies on In Vivo Function of Peroxiredoxins in Knockout Mice

Yu DY

Peroxiredoxins (Prxs) are a family of antioxidant proteins that reduce peroxide levels by using reducing agents such as thioredoxin. These proteins were characterized to have a number of cellular functions,...
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Effects of Free Fatty Acids on Glutathione Redox Status in Cultured Endothelial Cells

Park JY, Kim CH, Chung YE, Kim HK, Kim YI, Hong SK, Lee JD, Lee KU

  • KMID: 2331668
  • J Korean Diabetes Assoc.
  • 1998 Sep;22(3):262-270.
BACKGROUND: Although plasma free fatty acids (FFA) are frequently elevated in diabetes mellitus, its role in the pathogenesis of diabetic vascular complications has not been well investigated. Recent stuclies reported...
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A reconstituted HDL containing V156K or R173C apoA-I exhibited anti-inflammatory activity in apo-E deficient mice and showed resistance to myeloperoxidase-mediated oxidation

Cho KH, Kim JR

It has been hypothesized that blood infusion of reconstituted HDL (rHDL) is a possible therapeutic strategy for the treatment of coronary artery disese. To compare short-term anti-inflammatory activity of wildtype...
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A Memory Molecule, Ca2+/Calmodulin-Dependent Protein Kinase II and Redox Stress; Key Factors for Arrhythmias in a Diseased Heart

Song YH

Arrhythmias can develop in various cardiac diseases, such as ischemic heart disease, cardiomyopathy and congenital heart disease. It can also contribute to the aggravation of heart failure and sudden cardiac...
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Ritalinic Acid Stimulates Human Sperm Motility and Maintains Vitality In Vitro

Harlev A, Henkel R, Samanta L, Agarwal A

PURPOSE: To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. MATERIALS AND...
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Glucose-6-phosphate dehydrogenase deficiency does not increase the susceptibility of sperm to oxidative stress induced by Hâ‚‚Oâ‚‚

Roshankhah S, Rostami-Far Z, Shaveisi-Zadeh F, Movafagh A, Bakhtiari , Shaveisi-Zadeh J

OBJECTIVE: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzyme defect. G6PD plays a key role in the pentose phosphate pathway, which is a major source of nicotinamide adenine...
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Rapid uptake of oxidized ascorbate induces loss of cellular glutathione and oxidative stress in liver slices

Song JH, Simons C, Cao L, Shin SH, Hong M, Chung IM

  • KMID: 1097253
  • Exp Mol Med.
  • 2003 Apr;35(2):67-75.
The observation that ascorbate known to retain pro-oxidant properties induces cell death in a number of immortal cell lines, led us to examine its mechanism and whether it is involved...
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Effects of Reactive Oxygen Metabolite on the Calcium Transport of Cardiac Mitochondria

Kim MS, Lee YS, Hong SC

BACKGROUND: Intracellular calcium overload is a common final feature of the ischemic-reperfused heart and mediates the genesis of irreversible cell damage. Reactive oxygen medabolites have been known to play and...
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