- Small Heterodimer Partner and Innate Immune Regulation
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Yuk JM, Jin HS, Jo EK
- KMID: 2169687
- Endocrinol Metab.
- 2016 Mar;31(1):17-24.
- doi: 10.3803/EnM.2016.31.1.17
The nuclear receptor superfamily consists of the steroid and non-steroid hormone receptors and the orphan nuclear receptors. Small heterodimer partner (SHP) is an orphan family nuclear receptor that plays an... -
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- Effect of cell-penetrating peptide-conjugated estrogen-related receptor beta on the development of mouse embryos cultured in vitro
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Yang NJ, Seol DW, Jo J, Jang HM, Yoon SY, Lee DR
- KMID: 2167483
- Clin Exp Reprod Med.
- 2014 Mar;41(1):1-8.
- doi: 10.5653/cerm.2014.41.1.1
OBJECTIVE: Estrogen related receptor beta (Esrrb) is a member of the orphan nuclear receptors and may regulate the expression of pluripotency-related genes, such as Oct4 and Nanog. Therefore, in the... -
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- Estrogen modulates transactivations of SXR-mediated liver X receptor response element and CAR-mediated phenobarbital response element in HepG2 cells
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Min G
- KMID: 994396
- Exp Mol Med.
- 2010 Nov;42(11):731-738.
- doi: 10.3858/emm.2010.42.11.074
The nuclear receptors, steroid and xenobiotic receptor (SXR) and constitutive androstane receptor (CAR) play important functions in mediating lipid and drug metabolism in the liver. The present study demonstrates modulatory... -
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- Effect of Thyroid Hormone to the Expression of ATP-binding Cassette Transporter ABCG5
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Ahn HY, Jang JM, Lee KJ, Kim SH, Kim KW, Park DJ, Jang HC, Park YJ
- KMID: 2012970
- J Korean Thyroid Assoc.
- 2011 May;4(1):39-46.
BACKGROUND AND OBJECTIVES: Excretion of bile acid and free cholesterol of bile was important to maintain cholesterol homeostasis. ATP-binding cassette transporter G5 (ABCG5) and G8 (ABCG8) promoted biliary cholesterol excretion.... -
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- Over-expression of Liver X Receptor-alpha(LXR alpha by TO901317 Exaggerated the Production of Mesangial Matrix
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Chin HJ, Fu YY, Song YR, Lee ES, Lee YM, Kim SG, Na KY, Kim S, Chae DW
- KMID: 2253063
- Korean J Nephrol.
- 2010 Mar;29(2):189-197.
PURPOSE: To provide the insight into the role of LXR alpha on the progression of diabetic nephropathy, we measured the production of extracellular matrix in the cultured mesangial cells treated... -
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- Cilostazol inhibits insulin-stimulated expression of sterol regulatory binding protein-1c via inhibition of LXR and Sp1
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Jung YA, Kim HK, Bae KH, Seo HY, Kim HS, Jang BK, Jung GS, Lee IK, Kim MK, Park KG
- KMID: 2155338
- Exp Mol Med.
- 2014 Jan;46(1):e73.
- doi: 10.1038/emm.2013.143
Hepatic steatosis is common in obese individuals with hyperinsulinemia and is an important hepatic manifestation of metabolic syndrome. Sterol regulatory binding protein-1c (SREBP-1c) is a master regulator of lipogenic gene... -
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- Effect of Bilirubin on Triglyceride Synthesis in Streptozotocin-Induced Diabetic Nephropathy
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Xu J, Lee ES, Baek SH, Ahn SY, Kim S, Na KY, Chae DW, Chin HJ
- KMID: 2069807
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S155-S163.
- doi: 10.3346/jkms.2014.29.S2.S155
We aimed to elucidate the effect of bilirubin on dyslipidemia and nephropathy in a diabetes mellitus (DM) type I animal model. Sprague-Dawley rats were separated into control, DM, and bilirubin-treated... -
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