- Validation of a Multiplexed Opsonophagocytic Assay for 11 Additional Pneumococcal Serotypes and Its Application to Functional Antibody Evaluation Induced by Pneumococcal Polysaccharide Vaccine
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Cha J, Kim HW, Lee JH, Lee S, Kim KH
- KMID: 2428639
- J Korean Med Sci.
- 2018 Dec;33(51):e340.
- doi: 10.3346/jkms.2018.33.e340
BACKGROUND: Various pneumococcal vaccines have been evaluated for immunogenicity by opsonophagocytic assay (OPA). A multiplexed OPA (MOPA) for 13 pneumococcal serotypes was developed by Nahm and Burton, and expanded to... -
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- Opsonophagocytic Antibodies to Serotype Ia, Ib, and III Group B Streptococcus among Korean Infants and in Intravenous Immunoglobulin Products
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Kim HW, Lee JH, Cho HK, Lee H, Seo HS, Lee S, Kim KH
- KMID: 2375072
- J Korean Med Sci.
- 2017 May;32(5):737-743.
- doi: 10.3346/jkms.2017.32.5.737
Group B streptococcus (GBS) infection is a leading cause of sepsis and meningitis among infants, and is associated with high rates of morbidity and mortality in many countries. Protection against... -
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- Functional Immunity to Cross-Reactive Serotype 6A Induced by Serotype 6B in Pneumococcal Polysaccharide Vaccine
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Kim KH
- KMID: 2278624
- Korean J Pediatr.
- 2005 May;48(5):506-511.
PURPOSE: Streptococcus pneumoniae serotype 6B and 6A are important pathogens in pneumococcal infections. It is commonly assumed that the 6B vaccines elicit antibodies cross-reacting with the 6A serotype and the... -
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- Functional Antibody Responses to Seven Serotypes in Pneumococcal Polysaccharide Vaccine in Children
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Park JH, Kim HJ, Hong YM, Kim KH
- KMID: 1655412
- Korean J Pediatr.
- 2004 Nov;47(11):1173-1180.
PURPOSE: Streptococcus pneumoniae is an important pathogen in children as well as in elderly people. The aim of this study was to assess the opsonization activity of pneumococal capsular antibody... -
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- Neutrophil Function and the Effect of Chemotherapy on Neurophil Function in Patients with Cancer
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Lee SN, Park LG
- KMID: 1965797
- Ewha Med J.
- 1989 Dec;12(4):253-263.
- doi: 10.12771/emj.1989.12.4.253
It has been recognized for a long time that human malignant diseases are associated with immune deficiency states. Impaired phagocytic function, low levels of plasma opsonins, impaired bactericidal activity of... -
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- Downstream components of RhoA required for signal pathway of superoxide formation during phagocytosis of serum opsonized zymosans in macrophages
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Kim JS, Kim JG, Jeon CY, Won HY, Moon MY, Seo JY, Kim JI, Kim J, Lee JY, Choi SY, Park J, Yoon Park , Ha KS, Kim PH, Park JB
- KMID: 1116203
- Exp Mol Med.
- 2005 Dec;37(6):575-587.
Rac1 and Rac2 are essential for the control of oxidative burst catalyzed by NADPH oxidase. It was also documented that Rho is associated with the superoxide burst reaction during phagocytosis... -
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