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Specific and common antigens of Clonorchis sinensis and Opisthorchis viverrini (Opisthorchidae, Trematoda)

Choi MH, Ryu JS, Lee MJ, Li S, Chung BS, Chai JY, Sithithaworn P, Tesana S, Hong ST

The antigenic characterizations and serological reactions of human liver flukes, Clonorchis sinensis and Opisthorchis viverrini, were analyzed by immunoblot. The antigenic profiles of the crude extract of Clonorchis contained major...
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Chronic Opisthorchis viverrini Infection and Associated Hepatobiliary Disease Is Associated with Iron Loaded M2-like Macrophages

Bility MT, Sripa B

Chronic Opisthorchis viverrini-induced hepatobiliary disease is associated with significant leukocyte infiltration, including activated macrophages; however, the polarization of infiltrating macrophages remains to be fully characterized. In this study, we characterized...
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Prevalence of Opisthorchis viverrini-Like Fluke Infection in Ducks in Binh Dinh Province, Central Vietnam

Dao TT, Abatih EN, Nguyen TT, Tran HT, Gabriël S, Smit S, Le PN, Dorny P

Following the first report of Opisthorchis viverrini infection in a domestic duck in Phu My District of Binh Dinh Province, Central Vietnam, many other cases were observed in the province....
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Opisthorchis felineus and Metorchis bilis Metacercariae in Cyprinid Fish Leuciscus idus in Nura-Sarysu River, Kazakhstan

Kiyan VS, Bulashev A, Katokhin A

Aim of the present study was to provide presence of opisthorchiid metacercariae in cyprinid fish Leuciscus idus in Nura-Sarysu river, Kazakhstan. Infection rate of the ides by the metacercariae was...
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Liver Flukes: the Malady Neglected

Lim JH

Liver fluke disease is a chronic parasitic inflammatory disease of the bile ducts. Infection occurs through ingestion of fluke-infested, fresh-water raw fish. The most well-known species that cause human infection...
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Comparative Characterization of Four Calcium-Binding EF Hand Proteins from Opisthorchis viverrini

Emmanoch P, Kosa N, Vichasri-Grams S, Tesana S, Grams R, Geadkaew-Krenc A

Four isoforms of calcium binding proteins containing 2 EF hand motifs and a dynein light chain-like domain in the human liver fluke Opisthorchis viverrini, namely OvCaBP1, 2, 3, and 4,...
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Curcumin Prevents Bile Canalicular Alterations in the Liver of Hamsters Infected with Opisthorchis viverrini

Jattujan P, Pinlaor S, Charoensuk L, Arunyanart C, Welbat JU, Chaijaroonkhanarak W

Opisthorchis viverrini infection causes inflammation and liver injury leading to periductal fibrosis. Little is known about the pathological alterations in bile canaliculi in opisthorchiasis. This study aimed to investigate bile...
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Molecular and Biochemical Characterization of Opisthorchis viverrini Calreticulin

Chaibangyang W, Geadkaew-Krenc A, Vichasri-Grams S, Tesana S, Grams R

Calreticulin (CALR), a multifunctional protein thoroughly researched in mammals, comprises N-, P-, and C-domain and has roles in calcium homeostasis, chaperoning, clearance of apoptotic cells, cell adhesion, and also angiogenesis....
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Archaeoparasitological Analysis of Samples from the Cultural Layer of Nadym Gorodok dated Back to the 14th-Late 18th Centuries

Slepchenko SM, Kardash OV, Slavinsky , Ivanov SN, Sergeyevna RD, Tsybankov , Shin DH

An archaeoparasitological analysis of the soil samples from Nadym Gorodok site of Western Siberia has been carried out in this study. The archaeological site was dated as the 13 to...
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Distribution and Abundance of Opisthorchis viverrini Metacercariae in Cyprinid Fish in Northeastern Thailand

Pinlaor S, Onsurathum S, Boonmars T, Pinlaor P, Hongsrichan N, Chaidee A, Haonon O, Limviroj W, Tesana S, Kaewkes S, Sithithaworn P

To increase public health awareness for prevention of opisthorchiasis caused by eating raw freshwater fish, the distribution and abundance of Opisthorchis viverrini metacercariae (OV MC) was investigated in freshwater fish...
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Effect of Temperature on the Killing of Opisthorchis viverrini Eggs In Vitro

Boueroy P, Duenngai K, Eamudomkarn C, Sripan P, Boonmars T, Pumhirunroj B, Artchayasawat A, Songsri J, Chomphumee K, Rattanasuwan P, Laummaunwai P, Khueangchiangkhwang S, Boonjaraspinyo S

Contaminated liver fluke egg in the environment has led to the high prevalence of human opisthorchiasis associated with cholangiocarcinoma in Southeast Asia. To find the effective lessening methods of Opisthorchis...
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The epidemiology and risk factors of hilar cholangiocarcinoma

Ryu JK

  • KMID: 2259042
  • Korean J Med.
  • 2010 Dec;79(6):593-596.
A hilar cholangiocarcinoma is a cholangiocarcinoma occurring at the confluence of the right and left hepatic bile ducts which is called as Klatskin tumor. Because hilar cholangiocarcinoma is the most...
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Molecular Differentiation of Opisthorchis viverrini and Clonorchis sinensis Eggs by Multiplex Real-Time PCR with High Resolution Melting Analysis

Kaewkong W, Intapan PM, Sanpool O, Janwan P, Thanchomnang T, Laummaunwai P, Lulitanond V, Doanh PN, Maleewong

Opisthorchis viverrini and Clonorchis sinensis are parasites known to be carcinogenic and causative agents of cholangiocarcinoma in Asia. The standard method for diagnosis for those parasite infections is stool examination...
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The prevalence of feline parasites in Suwon, Korea

Youn H, Cho MR, Lim YS, Kim KH, Bae BK, Shin N, Nam HW

  • KMID: 1435815
  • Korean J Vet Res.
  • 2012 Jun;52(2):65-68.
Feline parasites were investigated in the area of Suwon in Korea from September to October, 2003. Wild cat had spread to zoonotic parasites, these parasites could cause infection with a...
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Codon Usage Patterns of Tyrosinase Genes in Clonorchis sinensis

Bae YA

Codon usage bias (CUB) is a unique property of genomes and has contributed to the better understanding of the molecular features and the evolution processes of particular gene. In this...
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Subsets of Inflammatory Cytokine Gene Polymorphisms are Associated with Risk of Carcinogenic Liver Fluke Opisthorchis viverrini-Associated Advanced Periductal Fibrosis and Cholangiocarcinoma

Surapaitoon A, Suttiprapa S, Mairiang E, Khuntikeo , Pairojkul , Bethony J, Brindley P, Sripa B

Opisthorchis viverrini infection induces chronic inflammation, and a minor proportion of infected individuals develop advanced periductal fibrosis (APF) and cholangiocarcinoma (CCA). Inflammatory cytokines and/or their gene polymorphisms may link to...
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Liver Flukes and Cholangiocarcinoma: Mechanism of Carcinogenesis

Lee SO, Kim SH

  • KMID: 2258992
  • Korean J Med.
  • 2011 Mar;80(3):273-279.
It has been clarified that chronic infection with viruses such as hepatitis B virus, bacteria such as Helicobacter pylori and parasites contribute to carcinogenesis in human. Three helminth infections have...
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High Prevalence of Opisthorchis viverrini Infection in a Riparian Population in Takeo Province, Cambodia

Yong TS, Shin EH, Chai JY, Sohn WM, Eom KS, Lee DM, Park K, Jeoung HG, Hoang EH, Lee YH, Woo HJ, Lee JH, Kang SI, Cha JK, Lee KH, Yoon CH, Sinuon M, Socheat D

Opisthorchis viverrini infection was found to be highly prevalent in 3 riverside villages (Ang Svay Chek A, B, and C) of the Prey Kabas District, Takeo Province. This area is...
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Echinostoma ilocanum Infection in Two Residents of Savannakhet Province, Lao PDR

Chai JY, Sohn WM, Cho J, Eom KS, Yong TS, Min DY, Hoang EH, Phommasack B, Insisiengmay B, Rim HJ

Adult specimens of Echinostoma ilocanum (Garrison, 1908) Odhner, 1911 (Trematoda: Echinostomatidae) were recovered from 2 riparian people who resided along the Mekong River in Savannakhet Province, Lao PDR. In fecal...
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Studies on the Transmissibility of Pathogenic-Organisms to Liver by Larvae of Liver Fluke and Hookworm

Soh CT, Im KI, Lim HC

In order to confirm whether the migrating larvae of parasites could carry pathogenic organisms into liver and cause hepatitis, a series of experiments has been carried out. The summary of...
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