- The Study on Vitrification and Ultrarapid Thawing of Human Embryonic Stem Cells
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Moon SY, Park YB, Kim HS, Sung KC, Oh SK, Chun DW, Suh CS, Choi YM, Kim JG, Lee JY, Kim SH
- KMID: 1979163
- Korean J Fertil Steril.
- 2002 Mar;29(1):13-20.
OBJECTIVE: This study was carried out to establish the effectiveness of the vitrification method and the optimal cryoprotectants in the cryopreservation of human embryonic stem cells (ESC). MATERIALS AND METHODS: Human... -
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- The potential role of COX-2 in cancer stem cell-mediated canine mammary tumor initiation: an immunohistochemical study
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Huang J, Zhang D, Xie F, Lin D
- KMID: 2164533
- J Vet Sci.
- 2015 Jun;16(2):225-231.
- doi: 10.4142/jvs.2015.16.2.225
Increasing evidence suggests that cancer stem cells (CSCs) are responsible for tumor initiation and maintenance. Additionally, it is becoming apparent that cyclooxygenase (COX) signaling is associated with canine mammary tumor... -
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- Correlation of Cancer Stem-Cell Markers OCT4, SOX2, and NANOG with Clinicopathological Features and Prognosis in Operative Patients with Rectal Cancer
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You L, Guo X, Huang Y
- KMID: 2418846
- Yonsei Med J.
- 2018 Jan;59(1):35-42.
- doi: 10.3349/ymj.2018.59.1.35
PURPOSE: To investigate the association of cancer stem-cell markers [octamer-binding transcription factor 4 (OCT4), sex determining region Y-box 2 (SOX2), and Nanog homebox (NANOG)] expression with clinicopathological properties and overall... -
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- Establishment of Hepatocellular Cancer Induced Pluripotent Stem Cells Using a Reprogramming Technique
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Kim HJ, Jeong J, Park S, Jin YW, Lee SS, Lee SB, Choi D
- KMID: 2412193
- Gut Liver.
- 2017 Mar;11(2):261-269.
- doi: 10.5009/gnl15389
BACKGROUND/AIMS: Cancer is known to be a disease by many factors. However, specific results of reprogramming by pluripotency-related transcription factors remain to be scarcely reported. Here, we verified potential effects... -
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- Constitutive stabilization of hypoxia-inducible factor alpha selectively promotes the self-renewal of mesenchymal progenitors and maintains mesenchymal stromal cells in an undifferentiated state
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Park IH, Kim KH, Choi HK, Shim JS, Whang SY, June Hahn , Kwon OJ, Oh IH
- KMID: 2154263
- Exp Mol Med.
- 2013 Sep;45(9):e44.
With the increasing use of culture-expanded mesenchymal stromal cells (MSCs) for cell therapies, factors that regulate the cellular characteristics of MSCs have been of major interest. Oxygen concentration has been... -
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- Enhanced proliferation and differentiation of Oct4- and Sox2-overexpressing human adipose tissue mesenchymal stem cells
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Han SM, Han SH, Coh YR, Jang G, Chan Ra J, Kang SK, Lee HW, Youn HY
- KMID: 2155366
- Exp Mol Med.
- 2014 Jun;46(6):e101.
- doi: 10.1038/emm.2014.28
Mesenchymal stem cells (MSCs) are attractive candidates for clinical repair or regeneration of damaged tissues. Oct4 and Sox2, which are essential transcription factors for pluripotency and self-renewal, are naturally expressed... -
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- Stemness Evaluation of Mesenchymal Stem Cells from Placentas According to Developmental Stage: Comparison to Those from Adult Bone Marrow
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Sung HJ, Hong SC, Yoo JH, Oh JH, Shin HJ, Choi IY, Ahn KH, Kim SH, Park Y, Kim BS
- KMID: 2157843
- J Korean Med Sci.
- 2010 Oct;25(10):1418-1426.
- doi: 10.3346/jkms.2010.25.10.1418
This study was done to evaluate the stemness of human mesenchymal stem cells (hMSCs) derived from placenta according to the development stage and to compare the results to those from... -
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- Alterations of proliferative and differentiation potentials of human embryonic stem cells during long-term culture
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Park YB, Kim YY, Oh SK, Chung SG, Ku SY, Kim SH, Choi YM, Moon SY
- KMID: 1103593
- Exp Mol Med.
- 2008 Feb;40(1):98-108.
- doi: 10.3858/emm.2008.40.1.98
Human embryonic stem cells (hESCs) are considered to be able to stably maintain their characteristics in vitro for prolonged periods, but we had previously encountered changes in proliferative ability and... -
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