- Current status and perspectives of researches on programmed cell death in immune system
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Chung YH
- KMID: 2365358
- Allergy.
- 1995 Dec;15(4):569-595.
Programmed cell death(PCD), or apoptosis, is a distinct process of cell death in response to specific physiological or toxic signal. This genetically programmed form of cellular suicide is intimately involved... -
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- Correlation between Cervical Neoplasia and Apoptosis
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Noh HT, Lee CH
- KMID: 2261322
- Korean J Obstet Gynecol.
- 1999 Feb;42(2):369-376.
OBJECTIVE: The kinetic indices of apoptosis and cell proliferation m a histopathologic spectrum of the cervical neoplasia were evaluated to clarify the correlation between cervical neoplasm and apoplasis. Specific lesioas... -
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- Study of Detection Method of Apoptosis in Colorecteal Cancer Tissue
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Kim KH, Shim KS, Kim SS, Koo H, Park EB
- KMID: 1964772
- Ewha Med J.
- 1997 Jun;20(2):165-172.
- doi: 10.12771/emj.1997.20.2.165
OBJECTIVES: Apoptosis is a specific mode of cell death recognized by a characteristic pattern of morphological, biochemical, and molecular changes, There are several methods of detection of apoptosis. Morphological changes... -
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- ENCODE: A Sourcebook of Epigenomes and Chromatin Language
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Yavartanoo M, Choi JK
- KMID: 1806264
- Genomics Inform.
- 2013 Mar;11(1):2-6.
- doi: 10.5808/GI.2013.11.1.2
Until recently, since the Human Genome Project, the general view has been that the majority of the human genome is composed of junk DNA and has little or no selective... -
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- Systemic Lupus Erythematosus and Apoptosis
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Yoo DH
- KMID: 1542329
- J Korean Rheum Assoc.
- 1997 Jan;4(1):1-10.
Systemic lupus erythematosus is a prototype of systemic autoimmune disease which is characterized by polyclonal B cell activation and production of various autoantibodies, especially antibodies against nucleosome. The pathogenesis of... -
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- Epigenetics: A key paradigm in reproductive health
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Bunkar N, Pathak N, Lohiya NK, Mishra PK
- KMID: 2308892
- Clin Exp Reprod Med.
- 2016 Jun;43(2):59-81.
- doi: 10.5653/cerm.2016.43.2.59
It is well established that there is a heritable element of susceptibility to chronic human ailments, yet there is compelling evidence that some components of such heritability are transmitted through... -
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- Comparison between Therapeutic Efficacies of Histone Deacetylase Inhibitors and Established Drug Regimens Against Breast Cancer Cells using the Histoculture Drug Response Assay
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Seo JY, Lee YM, Cho DH, Roh SA, Ro SG, Hyun YL, Kim SY, Kim YS, Kim TW, Ahn SH, Kim JC
- KMID: 2175513
- J Breast Cancer.
- 2009 Dec;12(4):241-248.
- doi: 10.4048/jbc.2009.12.4.241
PURPOSE: Histone deacetylase inhibitors (HDACIs) induce accumulation of acetylated histones in nucleosomes, which lead to reactivate gene expression and inhibit the growth and survival of tumor cells. This study evaluated... -
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- The Mechanism of Interferon-gamma Induced Cytotoxicity on the Lung Cancer Cell Line, A549
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Oh YM, Yoo CG, Chung HS, Kim YW, Han SK, Shim YS
- KMID: 2317974
- Tuberc Respir Dis.
- 1996 Feb;43(1):63-68.
BACKGROUND: Interferon-gamma has various biologic effects, including antiviral effect, antitumor proliferative effect, activation of macrophage and B lymphocyte, and increased expression of major histocompatibility complex. Especially, antitumor proliferative effect of... -
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- Analysis of Gene Expression in Cyclooxygenase-2-Overexpressed Human Osteosarcoma Cell Lines
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Han JA, Kim JY, Kim JI
- KMID: 2391504
- Genomics Inform.
- 2014 Dec;12(4):247-253.
- doi: 10.5808/GI.2014.12.4.247
Osteosarcoma is the most common primary bone tumor, generally affecting young people. While the etiology of osteosarcoma has been largely unknown, recent studies have suggested that cyclooxygenase-2 (COX-2) plays a... -
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- Epigenetic Modification in Systemic Rheumatic Diseases
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Lee J, Kim HR, Lee SH, Kim HY
- KMID: 2222752
- J Rheum Dis.
- 2013 Jun;20(3):140-148.
- doi: 10.4078/jrd.2013.20.3.140
Epigenetics is defined as an inheritable effect that influences gene activity, but does not involve a change in DNA sequence. Epigenetic gene regulation has an essential role in determining individual... -
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- Methylglyoxal Induces Apoptosis Mediated by Reactive Oxygen Species in Bovine Retinal Pericytes
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Kim J, Son JW, Lee JA, Oh YS, Shinn SH
- KMID: 1785701
- J Korean Med Sci.
- 2004 Feb;19(1):95-100.
- doi: 10.3346/jkms.2004.19.1.95
One of the histopathologic hallmarks of early diabetic retinopathy is the loss of pericytes. Evidences suggest that the pericyte loss in vivo is mediated by apoptosis. However, the underlying cause... -
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