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Effects of Mumps Virus Nucleocapsid Protein on the Viral Replication and Apoptosis in VeroE6 Cells

Kim SH, Song KJ

  • KMID: 1615500
  • J Bacteriol Virol.
  • 2003 Sep;33(3):193-201.
Apoptosis, as a part of the natural defense mechanisms that protect against viral infection, plays a vital role in the pathogenic mechanisms. It also plays a key role in the...
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The Role of Noncoding Region in Hantaan Viral S Genome for Expression of Nucleocapsid Protein

Yu CH, Lee YS, Lee HD, Park C, Park KY, Lee PW

  • KMID: 1896561
  • J Korean Soc Virol.
  • 2000 Mar;30(1):39-49.
The genome of Hantaan virus, the prototype of the hantavirus genus, is composed of three segmented, single stranded negative sense RNA genome. The 5' and 3' termini of the Hantaan...
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Genetic diversity of nucleocapsid genes of recent porcine epidemic diarrhea viruses isolated in Korea

Kim K, Park Y, Park B, Truong QL, Park S, Kim J, Hahn TW

Porcine epidemic diarrhea virus (PEDV), a porcine enteropathogenic coronavirus, causes lethal watery diarrhea in piglets, resulting in large economic losses because of high mortality. In November 2013, PEDV reemerged in...
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Development and characterization of stable cell lines constitutively expressing the porcine reproductive and respiratory syndrome virus nucleocapsid protein

Sagong M, Park CK, Kim SH, Moon SU, Cho SC, Lee C

Despite global efforts to control porcine reproductive and respiratory syndrome virus (PRRSV) infection, the virus continues to cause economic problems in the swine industry worldwide. In this study, we attempted...
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Intracellular Localization of the Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein

Yun SI, Choi YJ, Song BH, Kang SY, Lee YM

Porcine reproductive and respiratory syndrome virus (PRRSV) is a small enveloped, positive-stranded RNA virus belonging to the family Arteriviridae. It causes the porcine reproductive and respiratory syndrome in swine. The...
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Production of specific antibodies against SARS-coronavirus nucleocapsid protein without cross reactivity with human coronaviruses 229E and OC43

Lee HK, Lee BH, Seok SH, Baek MW, Lee HY, Kim DJ, Na YR, Noh KJ, Park SH, Kumar DN, Kariwa H, Nakauchi M, Heo SJ, Park JH

Severe acute respiratory syndrome (SARS) is a life-threatening disease for which accurate diagnosis is essential. Although many tools have been developed for the diagnosis of SARS, false-positive reactions in negative...
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Comparative study of synonymous codon usage variations between the nucleocapsid and spike genes of coronavirus, and C-type lectin domain genes of human and mouse

Ahn I, Jeong BJ, Son HS

Coronaviruses (CoVs) are single-stranded RNA viruses which contain the largest RNA genomes, and severe acute respiratory syndrome coronavirus (SARS-CoV), a newly found group 2 CoV, emerged as infectious disease with...
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Molecular characterizations of phosphoprotein of rabies virus circulating in Korea

Kim HH, Yang DK, Jeon JK, Cho SD, Song JY

  • KMID: 1435794
  • Korean J Vet Res.
  • 2012 Mar;52(1):9-18.
Rabies is a major zoonotic disease that causes approximately 55,000 human deaths worldwide on an annual basis. The nucleocapsid protein and glycoprotein genes of the Korean rabies virus (RABV) have...
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Detection of canine respiratory coronavirus from dogs with respiratory disease

Hong S, Lee HY, Kim O

Canine respiratory coronavirus (CRCoV) is commonly associated with canine kennel cough worldwide. Clinically infected dogs present coughing, sneezing, and nasal discharge. Severe infections may progress to pneumonia. Through serological surveys,...
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Production and Characterization of Monoclonal Antibodies Against Seoul Virus

Lee HW, Lee YJ, Song KJ, Kee SH, Choi YJ, Song JW, Cho HW

  • KMID: 2146935
  • J Korean Soc Microbiol.
  • 1998 Feb;33(1):27-38.
Hantaviruses are members of the family Bunyaviridae, the etiologic agents of Hemorrhagic fever with renal syndrome (HFRS) and Hantavirus Pulmonary Syndrome (HPS). They are negative-sense, single-stranded RNA viruses possessing a...
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In vitro Transcription of Prospect Hill virus S Genome Segment Produced by RT-PCR

Lee PW, Park MS

  • KMID: 2146936
  • J Korean Soc Microbiol.
  • 1998 Feb;33(1):39-48.
Prospect Hill virus (PHV) is related antigenically but distinct to Hantaan virus. As a member of genus Hantavirus, PHV has three segmented RNA genome. Among these segments, Small segment(S) encodes...
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Production and Characterization of Monoclonal Antibodies to Mumps Virus Isolated in Korea

Kim SH, Kee SH, Ahn JE, Song JW, Song KJ

  • KMID: 1615501
  • J Bacteriol Virol.
  • 2003 Sep;33(3):203-208.
Classical mumps patients develop bilateral or less commonly unilateral parotitis. Mumps virus belongs to the genus Rubulavirus in the family Paramyxoviridae. It contains single stranded RNA genome with negative polarity....
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Evaluation of two different enzyme-linked immunosorbent assay for severe fever with thrombocytopenia syndrome virus diagnosis

Yu MA, Jeong HW, Park SJ, Kim YI, Kwon HI, Kim EH, Si YJ, Yu KM, Robles NJ, Han HJ, Choi YK

To develop the large scale serological assay for severe fever with thrombocytopenia syndrome virus (SFTSV) infection, we evaluated two different enzyme-linked immunosorbent assay (ELISA) methods using nucleocapsid protein (NP) and...
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Targeted RNA recombination of the membrane and nucleocapsid protein genes between mouse hepatitis virus and bovine coronavirus

Koljesar G, Yoo D

  • KMID: 1119210
  • J Vet Sci.
  • 2001 Dec;2(3):149-157.
The targeted RNA recombination was attempted to substitute the membrane (M) protein gene and part of the nucleocapsid (N) protein gene of mouse hepatitis virus with the corresponding sequences from...
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An enhanced immunochromatographic strip test using colloidal gold nanoparticle-labeled dual-type N proteins for detection of antibodies to PRRS virus

Yu JE, Ouh IO, Kang H, Lee HY, Cheong KM, Cho IS, Cha SH

Porcine reproductive and respiratory syndrome (PRRS) is recognized as one of the most important infectious diseases causing serious economic loss in the swine industry worldwide. Due to its increasing genetic...
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Simultaneous Detection and Identification of Human Respiratory Syncytial Virus, Influenza Virus A ( H3N2 , H1N1 ) and B by One - tube Multiplex Reverse Transcription Polymerase Chain Reaction

Park YH, Woo YD, Kim SK, Bae HJ, Park SW

  • KMID: 1571509
  • J Bacteriol Virol.
  • 2001 Sep;31(3):269-274.
Respiratory syncytial virus (RSV) and Influenza virus are the most common pathogen for causing severe upper respiratory infection in all age groups. A multiplex reverse transcription polymerase chain reaction (RT-PCR)...
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The Supressive Effects of Integrin Antibodies on the Infection of Hantaan Virus in Fibroblasts

Park HS, Kim KD, Kim SK

Pathophysiological mechanism of hemorrhagic fever with renal syndrome (HFRS) is not fully understood. Major clinical findings of HFRS patients are widespread hemorrhage, acute renal failure and shock. Basic lesion is...
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Application of Hantavirus N Protein Expressed by E. coli System

Yu CH, Nam JH, Choi TK, Ju YR, Lee CH, Shin YH, Park KY

  • KMID: 2055007
  • J Bacteriol Virol.
  • 2004 Jun;34(2):147-155.
Hantaan viruses cause haemorrhagic fever with renal syndrome (HFRS), resulting in severe morbidity and mortality in humans. The genome of Hantaan virus is composed of three segmented and single stranded...
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A recombinant rabies virus (ERAGS) for use in a bait vaccine for swine

Yang DK, Kim HH, Choi SS, Lee SH, Cho IS

PURPOSE: Rabies viruses (RABV) circulating worldwide in various carnivores occasionally cause fatal encephalitis in swine. In this study, the safety and immunogenicity of a recombinant rabies virus, the ERAGS strain...
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Pathobiology of Paget's Disease of Bone

Galson DL, Roodman GD

Paget's disease of bone is characterized by highly localized areas of increased bone resorption accompanied by exuberant, but aberrant new bone formation with the primary cellular abnormality in osteoclasts. Paget's...
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