- Mildly Increased Mechanical Nociceptive Sensitivity in REV-ERBα Knock-out Mice
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Lee J, Ko HG, Kim K, Kaang BK
- KMID: 2362831
- Exp Neurobiol.
- 2016 Dec;25(6):342-346.
- doi: 10.5607/en.2016.25.6.342
Nociception is one of the most complex senses that is affected not only by external stimulation but also internal conditions. Previous studies have suggested that circadian rhythm is important in... -
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- Long-term effect of vehicle resolving capsaicin applied locally to rat peripheral nerves on heat nociception : Measured by behavioral tests
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Cheon JS
- KMID: 1692486
- J Korean Neuropsychiatr Assoc.
- 1993 Jul;32(4):554-563.
No abstract available. -
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- Nociception monitoring tools using autonomic tone changes for intraoperative analgesic guidance in pediatric patients
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Lim BG
- KMID: 2465334
- Anesth Pain Med.
- 2019 Oct;14(4):380-392.
- doi: 10.17085/apm.2019.14.4.380
Nociception monitoring devices using changes in autonomic nervous system activity have been developed in numerous ways. Although there have been few studies conducted on children, compared to the relatively higher... -
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- Intraoperative nociception monitoring
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Kang H
- KMID: 2148005
- Anesth Pain Med.
- 2015 Oct;10(4):227-234.
- doi: 10.17085/apm.2015.10.4.227
Monitoring depth of anesthesia has been an aim of anesthesia for several decades. Monitoring of clinical parameters, such as cardiovascular signs, sweating, tearing and pupil signs has been routinely used.... -
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- Participation of IL-1β in temporomandibular nociception in rats with CFA-induced inflammation
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Ju JS, Choi SH, Kim HJ, Son JY, Ahn DK
- KMID: 2354200
- Int J Oral Biol.
- 2016 Sep;41(3):125-131.
- doi: 10.11620/IJOB.2016.41.3.125
The aim of the present study was to develop an animal model for evaluation of temporomandibular (TMJ) nociception under TMJ inflammation. We also investigated the participation of IL-1β in inflammation-induced... -
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- Introduction of Visceral Pain Model to Test of Visceral Nociception in the Rats
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Lee CW
- KMID: 2104665
- J Korean Pain Soc.
- 1995 Apr;8(1):25-30.
Anlgesic agents against visceral pain typically rely on a noxious chemical irritation of the peritoneum, e. g., acetic acid and phenylquinone writhing test. While useful, this type of assay depends... -
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- The Correlation between Perception and Nociception Thresholds by Selected Current Stimuli in Adults
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Kang HC, Kim YI, Hwang KH, Kwak SD, Park W, Kim SY
- KMID: 2032292
- Korean J Anesthesiol.
- 1999 Mar;36(3):474-480.
- doi: 10.4097/kjae.1999.36.3.474
BACKGROUND: This study was designed to investigate the correlation between pain and non-pain sensation of the cutaneous nociceptors in healthy adults use 250 Hz and 5 Hz evoking neuroselective sinusoidal... -
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- Myofascial headache
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Choi SS
- KMID: 2046773
- Anesth Pain Med.
- 2008 Oct;3(4):233-240.
Pericranial myofascial tenderness is a common phenomenon in primary headache. Nociception from pericranial muscles may play a role in provoking or aggravating headaches. Conversely, the central mechanisms of headache are... -
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- The Role of Transient Receptor Potential Channel in Pain
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Jung SJ
- KMID: 2168188
- Hanyang Med Rev.
- 2011 May;31(2):116-122.
- doi: 10.7599/hmr.2011.31.2.116
Transient receptor potential (TRP) channels, a large family of receptor channel proteins, initially attracted researchers in the pain field as key molecules in nociception, but later they became known as... -
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- Antinociceptive Effects of Prim-O-Glucosylcimifugin in Inflammatory Nociception via Reducing Spinal COX-2
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Wu LQ, Li Y, Li YY, Xu SH, Yang ZY, Lin Z, Li J
- KMID: 2351691
- Biomol Ther.
- 2016 Jul;24(4):418-425.
- doi: 10.4062/biomolther.2015.168
We measured anti-nociceptive activity of prim-o-glucosylcimifugin (POG), a molecule from Saposhnikovia divaricate (Turcz) Schischk. Anti-nociceptive or anti-inflammatory effects of POG on a formalin-induced tonic nociceptive response and a complete Freund's... -
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- Acute Phase Protein Lipocalin-2 Is Associated with Formalin-induced Nociception and Pathological Pain
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Jha MK, Jeon S, Jin M, Lee WH, Suk K
- KMID: 2150790
- Immune Netw.
- 2013 Dec;13(6):289-294.
- doi: 10.4110/in.2013.13.6.289
Lipocalin-2 (LCN2) is an acute-phase protein induced by injury, infection, or other inflammatory stimuli. LCN2 binds small hydrophobic ligands and interacts with cell surface receptor to regulate diverse cellular processes.... -
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- Antinociceptive Effect of Intraperitoneally Administered 5,5-dimethyl-1-pyrroline N-oxide on Formalin Induced Nociception in Rats
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Chung WS, Go YG, Lee WH
- KMID: 2239836
- Korean J Anesthesiol.
- 2008 Mar;54(3):S35-S39.
- doi: 10.4097/kjae.2008.54.3.S35
BACKGROUND: Reactive oxygen species (ROS) is known to be involved in chronic and persistent pain.By using the ROS scavenger 5,5-dimethyl-1-pyrroline N-oxide (DMPO), we studied the effects of ROS on formalin-induced... -
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- Transient Receptor Potential (TRP) Channels
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Park SW
- KMID: 1455710
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2010 Feb;53(2):65-70.
- doi: 10.3342/kjorl-hns.2010.53.2.65
Transient receptor potential (TRP) protein is a superfamily of cation channels which have 6 transmembrane domains and mainly pass calcium ion through themselves. There are seven types of subfamilies in... -
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- The Ultrastructure of TRPV1-positive Nerve Terminals in the Human Tooth Pulp
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Kim YK, Ma SK, Jin MU, Kim SK, Bae YC
- KMID: 1510196
- Korean J Anat.
- 2006 Aug;39(4):297-303.
The vanilloid receptor TRPV1 has been suggested to play an important role in thermal nociception and inflammatory hyperalgesia. In our previous study, we examined the expression of TRPV1 and colocalization of TRPV1... -
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- Defensive Behavior against Noxious Heat Stimuli Is Declined with Aging Due to Decreased Pain-Associated Gene Expression in Drosophila
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Ghimire S, Kim MS
- KMID: 2380340
- Biomol Ther.
- 2015 May;23(3):290-295.
- doi: 10.4062/biomolther.2014.147
Aging is defined as a collective process that alters organism's functional capacity and appearance over the course of life. Apart from an increase in susceptibility to many diseases, aging affects... -
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- Antinociceptive Effects of Intrathecal Adenosine Receptors Subtype Agonists in the Formalin Test
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Yoon MH, Bae HB, Park HC, Choi JC, Choi JI
- KMID: 2104837
- J Korean Pain Soc.
- 2004 Dec;17(2):99-104.
- doi: 10.3344/jkps.2004.17.2.99
BACKGROUND: Adenosine has shown an antinociceptive action, which is mediated via spinal adenosine receptors. Previous studies have revealed the presence of four subtypes of adenosine receptor, A1, A2A, A2B and... -
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- Anti-nociceptive and Anti-inflammatory Properties of Ilex latifolia and its Active Component, 3,5-Di-caffeoyl Quinic Acid Methyl Ester
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Kim JY, Lee HK, Seong YH
- KMID: 2443106
- Nat Prod Sci.
- 2019 Mar;25(1):64-71.
- doi: 10.20307/nps.2019.25.1.64
The present study was conducted to investigate anti-nociceptive and anti-inflammatory effects of the leaves of Ilex latifolia Thunb (I. latifolia) in in vivo and in vitro. Writhing responses induced by... -
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- Antinociceptive Effects of Intrathecal Melatonin on Formalin: and Thermal-induced Pain in Rats
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Chung ST, Jin WJ, Bae HB, Kim SJ, Choi JI, Kang MW, Jeong CY, Yoon MH
- KMID: 2073918
- Korean J Pain.
- 2006 Dec;19(2):137-141.
- doi: 10.3344/kjp.2006.19.2.137
BACKGROUND: It has been known that melatonin is involved in the modulation of nociceptive transmission. However, the effect of melatonin administered spinally has not been examined. Therefore, we... -
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- Evaluation for the Effects of Intrathecal Sildenafil on the Formalin- and Thermal-induced Nociception of Rats
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Yoon MH, Bae HB, Shin DJ, Kim CM, Jeong ST, Kim SJ, Choi JI
- KMID: 2278011
- Korean J Pain.
- 2006 Jun;19(1):17-21.
- doi: 10.3344/kjp.2006.19.1.17
BACKGROUND: Cyclic guanosine monophosphate (cGMP) plays an important role in the modulation of nociception. Although local sildenafil produces antinociception, by increasing cGMP through the inhibition of phosphodiesterase 5, the effect... -
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- The Antinociceptive Effect of Intrathecal Anticholinesterase on the Formalin Test in Rats
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Jung G, Yoon MH, Jeong SW, Kwak SH, Chung SS, Jeong CY
- KMID: 1936304
- Korean J Anesthesiol.
- 2000 May;38(5):887-893.
- doi: 10.4097/kjae.2000.38.5.887
BACKGROUND: Spinal anticholinesterase has been shown to have an antinociceptive action to acute noxious stimuli. The purpose of this study was to determine the effect of intrathecal anticholinesterase on the... -
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