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Clinical Observation on Antihypertensive Effect of Nicardipine Hydrochloride(Perdipine(R))

Song JS, Kim MS, Kim KS, Bae JH

The antihypertensive effect and side reactions of nicardipine were observed in 30 cases of essential hypertension, and following results were obtained. 1) Nicardipine has very good antihypertensive effect. After medication...
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Effect of Nicardipine on Pressor Response to Raised Intracranial Pressure and alpha-Adrenoceptor Agonist

Jung S, Kang SS

  • KMID: 1953084
  • J Korean Neurosurg Soc.
  • 1989 Jan;18(1):23-31.
The effect of nicardipine was investigated on hypertension due to raised intracranial pressure, pressor response of alpha-adrenoceptor agonists in the dissected thoracic aorta. Intracerebroventricular(icv) and intravenous(iv) nicardipine produced dose-dependent depressor...
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Effect of nicardipine nitroprusside and enalapril on the survival of random pattern skin flaps in rats

Kim HY, Kim BS, Im GY, Lee SY, Cho BH

  • KMID: 1921318
  • J Korean Soc Plast Reconstr Surg.
  • 1991 Nov;18(6):998-1005.
No abstract available.
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The Effects of Nicardipine in Experimentally-induced Retinal Ischemia-reperfusion Injury in Cats and Rabbits

Kim SY, Kwak MS, Lee SH, Lim JH

  • KMID: 2205682
  • J Korean Ophthalmol Soc.
  • 1999 Dec;40(12):3361-3367.
We investigated the effect of nicardipine on the retinal ischemia-reperfusion injury. After intravenous administration[30 microgram/kg] or intravitreal injection[10microgram] of nicardipine, total retinal ischemia for 60~90 minutes was induced in the...
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Effect of Nicardipine on Hemodynamic Responses to Endotracheal Intubation

Yoo ES, Han SG, Min SK, Park KS, Kim JH, Lee SY, Kim JS

BACKGROUD: Laryngoscopy and tracheal intubation often provoke an undesirable increase in blood pressure and heart rate. This study was done to examine the blunting effect of nicardipine on the adverse...
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Use of Nicardipine and Esmolol in the Anesthetic Management for Bilateral Pheochromocytoma: A case report

Lim PJ, Kwak HJ, Kwak HS

Pheochromocytoma stems from the chromaffin cell and mostly is located in the adrenal medulla. It is an important cause of secondary hypertension due to correction of hypertension by a resection...
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Nicardipine Augments Local Myocardial Perfusion after Coronary Artery Reperfusion in Dogs

Jang YH, Kim JM

Nicardipine is a potent coronary and systemic vasodilator without depression of ventricular function. We investigated the changes in local myocardial perfusion (LMP) according to the nicardipine administration after coronary reperfusion...
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Effect of Preventive Nicardipine on Hemodynamics Induced by Pneumoperitoneum during Laparoscopic Cholecystectomy

Jeong JH, Lim DG

BACKGROUND: Pneumoperitoneum for a laparoscopic cholecystectomy induces hemodynamic changes. The present study investigated the effect of preventive nicardipine on the hemodynamics induced by pneumoperitoneum during a laparoscopic cholecystectomy. METHODS: Forty five...
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The Effects of Continuous Nicardipine Infusion on Blood Pressure and Heart Rate during Endotracheal Intubation

Kim YS, Kang WJ, Kim SY, Choi YK, Shin OY

BACKGROUND: Laryngoscopy and tracheal intubation often induced an undesirable increase in blood pressure and heart rate. We evaluated the preventing effect of nicardipine infusion on the increase of the blood...
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Clinical Observation on Antihypertensive Effects of Nicardipine Hydrochloride(Perdipine(R))

Ryu WS, Oh BH, Lee MM, Seo JD, Lee YW

The antihypertensive effect of nicardipine was studied in 31 cases of essential hypertension and following results were obtained. 1) Daily dose was 30-60mg for 10 weeks. 2) Mean systolic and...
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Hypotensive Effect of Nicardipine(Perdipine(R)), A Clinical Study

Jeong MH, Kim SG, Park SJ, Park JC, Kang JC, Park OK

  • KMID: 2424974
  • Korean Circ J.
  • 1986 Dec;16(4):543-548.
A clinical study on the hypertensive effect of nicardipine was performed in 36 patients with essential hypertension. Nicardipine was administered 60mg a day in three divided doses for at least...
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The Effect of Nicardipine on Hemodynamic Responses to Tracheal Intubation during Inhalation with Sevoflurane

Jin IB, Lim HS, Son JS, Han YJ

BACKGROUND: Laryngoscopy and tracheal intubation often provoke an undesirable increase in blood pressure and heart rate. Nicardipine-induced reduction in blood pressure was greater with inhalational anesthetics than nicardipine alone. This...
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The Hemodynamic Response of Nicardipine for Hypertension Control during an Off-Pump Coronary Artery Bypass Graft

Kim SK, Park TK, Sin WH, Jang YH, Kim JM, Kim AR, Cheun JK

Drugs for acute blood pressure control are often required during a cardiovascular operation. Hypertension frequently occurs in an off-pump coronary artery bypass graft. The purpose of this study...
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Prolonged effect of nicardipine used for deliberate hypotension in scoliosis surgery: A case report

Oh SC, Chung K, Cho HS, Ryu KH, Cho SA, Lee SM

  • KMID: 1803582
  • Anesth Pain Med.
  • 2010 Oct;5(4):317-320.
Postoperative respiratory complications following scoliosis surgery are high incidence. In this case, fifty year-old male patient was admitted for thoracolumbar screw fixations and developed postoperative pulmonary edema. This was most...
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Blood Pressure Stabilizing Effect of Nicardipine at Endotracheal Intubation during Cesarean Section under General Anesthesia

Kim HS, Lee KC, Jung WS, Park YS, Lee D

  • KMID: 1741473
  • Anesth Pain Med.
  • 2006 Oct;1(2):111-115.
BACKGROUND: General anesthesia for cesarean section is usually maintained at a low dose after induction with using other agents. Many anesthesiologists have experience difficulty in maintaining stable blood pressure at...
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The relaxant effect of nicardipine on the isolated uterine smooth muscle of the pregnant rat

Kim DJ, Hwang MH, An TH, Jung KT

BACKGROUND: Nicardipine, a calcium channel blocker, is used to treat hypertension in pregnancy or preterm labor. The current study was conducted to investigate the relaxant effects of nicardipine on the...
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Inhibitory Effect of Nicardipine on Cardiovascular Stimulation by Tracheal Intubation

Lim JM, Kang KC, Chung CK

BACKGROUND: Direct laryngoscopy and tracheal intubation frequently induce transient hypertension, tachycardia and arrhythmia. This study was to evaluate the effect of nicardipine on the changes of the blood pressure and...
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The Comparison of the Effects of Nicardipine and Remifentanil on Fluctuation of Blood Pressure during Controlled Hypotension

Kim ES, Hwang BY, Kim CH

BACKGROUND: Controlled hypotension is used to reduce bleeding and improve surgical conditions during surgery. Nicardipine and remifentanil have been used to induce controlled hypotension in healthy patients. This study compared...
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Effects of a Combination of Nicardipine and Alfentanil on Hemodynamic Response after Endotracheal Intubation

Kim CM, Jeong ST, Kim SJ, Bae HB, Choi JI, Jeong SW, Chung SS, Yoo KY, Jeong CY, Yoon MH

BACKGROUND: The present study was designed to examine the effect of a combination of nicardipine and low dose alfentanil on hemodynamic response following endotracheal intubation. METHODS: Thirty patients (20-65 yr) were...
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The Effect of Systemic Nicardipine and Intracisternal Nicardipine on the Experimental Cerebral Vasospasm

Yoo KH, Park YK, Chong YK, Jeong HS, Suh JK, Lee HK, Lee KC, Chu JW

  • KMID: 2187747
  • J Korean Neurosurg Soc.
  • 1990 Sep;19(8-9):1169-1178.
This study reports the protective of systemic nicardipine and intracisternal nicardipine administration in the three-hemorrhage canine model of chronic cerebral vasospasm. Twenty-one dogs were assigned to one of three groups...
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