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Relative biological effectiveness of fast neutrons for apoptosis in mouse hair follicles

Lee HJ, Kim SH

This study compared the effects of high linear energy transfer (LET) fast neutrons on the induction of apoptosis in the hair follicles of ICR mice with those of low LET...
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Neutron Generation from a 24 MV Medical Linac

Lee JO, Jeong DH, Kang JK

  • KMID: 1591056
  • Korean J Med Phys.
  • 2005 Jun;16(2):97-103.
The energy spectra and dose calculations were performed for secondary neutrons from a 24 MV LINAC using MCNPX code (V2, 4, 0). The energy spectra for neutrons and photons emitted...
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Frequency of Micronuclei in Lymphocytes Following Gamma and Fast-neutron Irradiations

Kim SH, Cho CK, Kim TH, Chung IY, Yoo SY, Koh KH, Yun HG

  • KMID: 2196898
  • J Korean Soc Ther Radiol.
  • 1993 Jun;11(1):35-42.
The dose response of the number of micronuclei in cytokinesis-blocked (CB) lymphocytes after in vitro irradiation with -rays and neutrons in the 5 dose ranges was studied for a heterogeneous...
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Assembly Neutron Moderation System for BNCT Based on a ²⁵²Cf Neutron Source

Gheisari R, Mohammadi

In this paper, a neutron moderation system for boron neutron capture therapy (BNCT) based on a ²⁵²Cf neutron source is proposed. Different materials have been studied in order to produce...
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Trace element analysis by neutron activastion analysis in the human cancer tissue

Lim SM, Zo JI, Shim YM

  • KMID: 1685943
  • Korean J Nucl Med.
  • 1993 May;27(1):104-111.
No abstract available.
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Secondary Neutron Dose Measurement for Proton Line Scanning Therapy

Lee C, Lee S, Chung K, Han Y, Chung YH, Kim JS

Proton therapy is increasingly being actively used in the treatment of cancer. In contrast to photons, protons have the potential advantage of delivering higher doses to the cancerous tissue and...
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Dosimetric Characteristics of the KCCH Neutron Therapy Facility

Yoo SY, Noh SW, Chung HW, Cho CK, Koh KH, Bak JS, Eenmaa J

  • KMID: 1657615
  • J Korean Soc Ther Radiol.
  • 1988 Jun;6(1):85-92.
For the physical characterization of neutron beam, dosimetric measurements had been performed to obtain physical data of KCCH cyclotron-produced neutrons for clinical use. The results are presented and compared with...
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The RBE of Fractionated Fast Neutron on Walker 256 Carcinosarcoma with KCCH-Cyclotron

Yoo SY, Koh KH, Cho CK, Park CI, Kang WS

  • KMID: 2097254
  • J Korean Soc Ther Radiol.
  • 1987 Dec;5(2):75-82.
For evaluation of biological effect of p+(50.5 MeV) Be neutron beam produced by Korea Cancer Center Hospital(KCCH) cyclotron the RBE had been measured in experimental tumor Walker 256 carcinosarcoma as...
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Fast neutron irradiation deteriorates hippocampus-related memory ability in adult mice

Yang M, Kim H, Kim J, Kim SH, Kim JC, Bae CS, Kim JS, Shin T, Moon C

Object recognition memory and contextual fear conditioning task performance in adult C57BL/6 mice exposed to cranial fast neutron irradiation (0.8 Gy) were examined to evaluate hippocampus-related behavioral dysfunction following acute...
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The Combined Effect of Fast Neutron and hyperthermia according to the Sequence and Interval in MKN-45 Cells

Park WY, Ryu SR, Cho CG

  • KMID: 2198726
  • J Korean Soc Ther Radiol Oncol.
  • 1999 Mar;17(1):65-69.
PURPOSE: It has been well established that response of cells and tissues to low LET radiations(X- or grmma-ray) can enhanced by comdining with hyperthermia. However, There has been relatively little...
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Histopathological changes of testes and eyes by neutron irradiation with boron compounds in mice

Kim YJ, Yoon WK, Ryu SY, Chun KJ, Son HY, Cho SW

This study was performed to investigate the biological effects of boron neutron capture therapy (BNCT) on the testes and eyes in mice using HANARO Nuclear Reactor, Korea Atomic Energy Research...
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Dosimetry of the Low Fluence Fast Neutron Beams for Boron Neutron Capture Therapy

Lee DH, Ji YH, Lee DH, Park HJ, Lee S, Lee KH, Suh SH, Kim MS, Cho CK, Yoo SY, Yu HJ, Gwak HS, Rhee CH

  • KMID: 2323757
  • J Korean Soc Ther Radiol Oncol.
  • 2001 Mar;19(1):66-73.
PURPOSE: For the research of Boron Neutron Capture Therapy (BNCT), fast neutrons generated from the MC-50 cyclotron with maximum energy of 34.4 MeV in Korea Cancer Center Hospital were moderated...
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Different Expressions of HIF-1alpha, Bcl-2 and Baxin DU145 Prostate Cancer Cells Transplanted in Nude Mouse between X-Ray and Neutron Irradiation

Kong M, Kang JO, Kim SK, Shin DO, Park SH, Kim CJ, Chang HK

PURPOSE: To investigate the radiobiologic effects of neutron and X-ray irradiation on DU-145 prostate carcinoma cells by identifying the differences of HIF-1alpha expression and apoptosis. MATERIALS AND METHODS: Nude mice...
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Dosimetric Characteristics of a Thermal Neutron Beam Facility for Neutron Capture Therapy at HANARO Reactor

Lee DH, Kim MS, Suh S, Ji YH, Choi MS, Park JH, Kim KB, Yoo SY, Kim MS, Lee BC, Chun KJ, Cho JW

  • KMID: 1512443
  • Korean J Med Phys.
  • 2007 Jun;18(2):87-92.
A thermal neutron beam facility utilizing a typical tangential beam port for Neutron Capture Therapy was installed at the HANARO, 30 MW multi-purpose research reactor. Mixed beams with different physical...
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Development of Manual Multi-Leaf Collimator for Proton Therapy in National Cancer Center

Lee N, Kim TY, Kang DY, Choi JH, Jeong JH, Shin D, Lim YK, Park J, Kim TH, Lee SB

Multi-leaf collimator (MLC) systems are frequently used to deliver photon-based radiation, and allow conformal shaping of treatment beams. Many proton beam centers currently make use of aperture and snout systems,...
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Production of Re-188

Yang SD, Suh YS, Kim SU, Lim SM

  • KMID: 1926599
  • Korean J Nucl Med.
  • 1999 Apr;33(2):189-192.
188Re (beta=22 MeV; gamma=155 keV; T1/2=16.9 hours) is an attractive therapeutic radioisotope which is produced from decay of reactor-produced tungsten-188 parent (T1/2=69 days). 188W has been produced from the double...
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Basics of particle therapy I: physics

Park SH, Kang JO

With the advance of modern radiation therapy technique, radiation dose conformation and dose distribution have improved dramatically. However, the progress does not completely fulfill the goal of cancer treatment such...
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A Case of the Rhabdomyosarcoma Involving Maxillary Sinus and Orbit

Oh KK, Kwon SU, Kim YJ, Kim KH

  • KMID: 1873966
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Oct;41(10):1335-1338.
Recently, the 5-year survival rate of rhabdomyosarcoma has been greatly increased by combining therapy with radical surgery, radiation and chemotherapy. But it still has poor prognosis and there are few...
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Development of 166Ho-phytate Complex for Radiosynovectomy

Jalilian A, Anvari A, Bahrami-Samani A, Mazidi M, Ghannadi-Maragheh M

  • KMID: 2313131
  • Nucl Med Mol Imaging.
  • 2011 Jun;45(2):87-92.
BACKGROUND: 66Ho-chloride was obtained by bombardment of natural Ho(NO3)3 dissolved in acidic media using thermal neutron flux (4-5x10(13) n.cm(-2).s(-1)). METHODS: 166Ho-holmium chloride (185 MBq) was used successfully for preparation of 166Ho-phytate...
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Neutron Therapy of Unresectable and Recurrent Rectal Cancer

Yoo SY, Koh KH, Cho CK, Park WY, Yun HG, Shim JW

  • KMID: 2196910
  • J Korean Soc Ther Radiol.
  • 1993 Jun;11(1):127-132.
Total of 53 patients of unresectable and recurrent rectal cancer treated with neutron beam during the period from Oct. 1987 to Apr. 1992 were analyzed. Dose fractionation for the neutron...
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