- Topographical Propagation of alpha-synuclein Pathology in Parkinson's Disease: Phenomenology and Hypothetical Mechanism
-
Hyun M, Lee SJ
- KMID: 2165292
- Exp Neurobiol.
- 2009 Jun;18(1):19-25.
- doi: 10.5607/en.2009.18.1.19
Parkinson's disease is an age-related, slowly progressing neurodegenerative disorder characterized by abnormal deposition of aggregated alpha-synuclein in neuronal cell bodies (Lewy bodies) and neurites (Lewy neurites), as well as in... -
- CITED
-
- Close
- SHARE
-
- Close
- Neurotrophic and Neuritogenic Effects of Water Extracts of Rhizoma of Coptis chinensis Franch in PC12 Cells
-
Kwon GY, Choe BK, Kim SK
- KMID: 2071593
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):175-179.
Coptis chinensis (CC) is one of the traditional herbs used in Oriental medicine for the treatment of gastrointestinal disorders, anxiety, and insomnia. In this study, neurotrophic and neuritogenic effects of... -
- CITED
-
- Close
- SHARE
-
- Close
- An Autopsy Case of Alzheimer's Disease
-
Kwon T, Wona YJ, Lee JS, Ha H
- KMID: 2082727
- Korean J Leg Med.
- 2009 May;33(1):53-56.
Alzheimer's disease is the leading cause of dementia. We experienced a case of Alzheimer's disease who is 83-year-old woman killed by stab with a knife. She had been suffered from... -
- CITED
-
- Close
- SHARE
-
- Close
- Activation of small Rho GTPases by blebbistatin in PC12 cells
-
Kim EG, Shin EY
- KMID: 1498922
- J Biomed Res.
- 2013 Jun;14(2):60-64.
Neuronal differentiation is a complex biological process accompanying cytoskeletal reorganization, including neurite outgrowth and growth cone formation. Therefore, neuronal differentiation is critically regulated by actin-related signaling proteins, such as small... -
- CITED
-
- Close
- SHARE
-
- Close
- Reactive Oxygen Species are Involved in Y-27632-induced Neurite Outgrowth in PC12 Cells
-
Park SY, Moon SA, An JM, Kim DS, Seo JT
- KMID: 2368587
- Int J Oral Biol.
- 2016 Dec;41(4):231-236.
- doi: 10.11620/IJOB.2016.41.4.231
Inhibition of Rho-associated coiled coil-containing kinase (ROCK) has been reported to promote differentiation of neuronal cells. Here, we examined the effect of Y-27632, a ROCK inhibitor, on the outgrowth of... -
- CITED
-
- Close
- SHARE
-
- Close
- Alpha-Synuclein Function and Dysfunction on Cellular Membranes
-
Snead D, Eliezer D
- KMID: 2165535
- Exp Neurobiol.
- 2014 Dec;23(4):292-313.
- doi: 10.5607/en.2014.23.4.292
Alpha-synuclein is a small neuronal protein that is closely associated with the etiology of Parkinson's disease. Mutations in and alterations in expression levels of alpha-synuclein cause autosomal dominant early onset... -
- CITED
-
- Close
- SHARE
-
- Close
- Differentiation of adult canine bone marrow stem cells into neurons
-
Choi BH, Huh JY, Park DJ, Kim BY, Lee SH, Park SY
- KMID: 2058786
- J Korean Assoc Oral Maxillofac Surg.
- 2003 Feb;29(1):1-4.
In this study, we showed that neurons could be generated from adult canine bone marrow stem cells by culturing with DMSO/BHA/FeCl2. These neurons differentiated from the bone marrow stem cells... -
- CITED
-
- Close
- SHARE
-
- Close
- Differential Expressions of Synaptogenic Markers between Primary Cultured Cortical and Hippocampal Neurons
-
Kim YG, Lee YI
- KMID: 1438550
- Exp Neurobiol.
- 2012 Jun;21(2):61-67.
- doi: 10.5607/en.2012.21.2.61
Primary dissociated neuronal cultures are widely used research tools to investigate of pathological mechanisms and to treat various central and peripheral nervous system problems including trauma and degenerative neuronal diseases.... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effects of Venlafaxine on Neurite Growth of PC12 Cells
-
Oh HS, Choi JH, Lee JS, Lee JN, Choi MR, Chai YG, Kim SH, Yang BH
- KMID: 2202782
- J Korean Soc Biol Psychiatry.
- 2003 Nov;10(2):126-132.
OBJECTIVES: The purpose of this study is to examine the effects of venlafaxine, one of novel antidepressant drugs, on neurite growth in PC12 cells. METHODS: PC12 cells were cultured with NGF... -
- CITED
-
- Close
- SHARE
-
- Close
- Early Gastric Cancer with Neurofibroma Mimicking a Metastatic Node: A Case Report
-
Kim S, Kim YS, Kim JH, Min YD, Hong R
- KMID: 2372468
- J Gastric Cancer.
- 2013 Sep;13(3):185-187.
Neurofibromas are benign tumors that originate from the peripheral nerves, including neurites and fibroblasts. Generally, a solitary neurofibroma is located in the skin and rarely in other places. A 72-year-old... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of glial-neuronal cell co-culture on GFAP expression of astrocytes
-
Bae H, Park J, Yeon D
- KMID: 2285172
- Korean J Physiol Pharmacol.
- 1997 Jun;1(3):285-296.
Injury to brain transforms resting astrocytes to their reactive form, the hallmark of which is an increase in glial fibrillary acidic protein (GFAP), the major intermediate filament protein of their cell type.... -
- CITED
-
- Close
- SHARE
-
- Close
- beta-Amyloid Neurotoxicity on Basal Forebrain Cholinergic Neuron Cultures
-
Kim DH, Lee JH, Hong HN, Ko JY
- KMID: 1529459
- Korean J Anat.
- 1997 Jun;30(3):225-234.
beta-amyloid[Abeta] peptide consisting of 40 of 42 amino acids peptide is the principal constituent of senile plaques in Alzheimer`s disease. Recently, it has been demonstrated that this peptide and its... -
- CITED
-
- Close
- SHARE
-
- Close
- Nidogen Plays a Role in the Regenerative Axon Growth of Adult Sensory Neurons Through Schwann Cells
-
Lee HK, Seo IA, Suh DJ, Park HT
- KMID: 1779199
- J Korean Med Sci.
- 2009 Aug;24(4):654-659.
- doi: 10.3346/jkms.2009.24.4.654
We previously reported that nidogen is an extracellular matrix protein regulating Schwann cell proliferation and migration. Since Schwann cells play a critical role in peripheral nerve regeneration, nidogen may play... -
- CITED
-
- Close
- SHARE
-
- Close
- Centella asiatica enhances neurogenesis and protects neuronal cells against H2O2-induced oxidative injury
-
Kim H, Hong JT, Park MH
- KMID: 2169099
- J Biomed Res.
- 2015 Sep;16(3):121-128.
- doi: 10.12729/jbr.2015.16.3.121
Traditionally, Centella asiatica leaf extracts are used to treat neurodegenerative diseases in India. Centella asiatica is reportedly used to enhance memory and treat dementia, but its promoting effect on neural... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Midkine (MK) on Cultured Spinal Motor Neurons Damaged by Oxidative Stress
-
Park ST, Chung YT
- KMID: 2376329
- Korean J Phys Anthropol.
- 1996 Jun;9(1):101-107.
- doi: 10.11637/kjpa.1996.9.1.101
To evaluate the effect of midkine (MK), neurotrophic factor on cultured mouse spinal motor neuron, NSC-19 which was inhibited by glucose oxidase (GO)-induced oxygen radicals, MTT assay and neurofilament enzymeimmunoassay... -
- CITED
-
- Close
- SHARE
-
- Close
- Gangliosides Expression in Normal and Alzheimer Brains
-
Lee MC, Kim DL, Woo YJ, Kim SU, McGeer PL, Tai T
- KMID: 2274997
- Chonnam Med J.
- 2001 Sep;37(3):285-292.
Gangliosides are one of the major molecules in the central nervous system, however; localization of gangliosides has been hampered due to lack of sensitive and specific antibodies. We developed gangliosides... -
- CITED
-
- Close
- SHARE
-
- Close
- Axon Formation Follows Dendritic Differentiation in the Cultured Ventral Spinal Cord Neurons of Rat
-
Uhm CS, Park CH, Kwon KS, Rhyu IJ, Park SH, Chun YH
- KMID: 1530054
- Korean J Anat.
- 1998 Apr;31(2):181-189.
To understand the early cellular differentiation of neurons, we studied the differentiation of ventral spinal cord (VSC) neurons in culture. Immunofluorescence techniques with myelin associated protein 2 (MAP2) and phosphorylated... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibition of Neurite Outgrowth by Overexpression of Goa
-
Ghil SH, Kim BJ, Lee YD, Suh HY
- KMID: 1530296
- Korean J Anat.
- 1998 Dec;31(6):937-944.
G proteins mediate signal transductions generated by neurotransmitters and hormones. Among G proteins, Go is found in a large quantity in brain, but its precise role in the nervous tissue... -
- CITED
-
- Close
- SHARE
-
- Close
- Antioxidant Effect of Allopurinol on Oxygen Radical-Induced Toxicity in Cultured Mouse Cerebral Neurons
-
Park ST, Oh JM, Kim JJ, Choi MK, Chung YT
- KMID: 2283104
- Korean J Phys Anthropol.
- 1998 Dec;11(2):307-315.
In order to elucidate the neurotoxic effect of oxygen radicals on cultured mouse cerebral neurons, the neurotoxicity induced by xanthine oxidase (XO) and hypoxanthine (HX), was evaluated by MTT assay.... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibition of Neurite Outgrowth by Stably Expressed Go alpha in F11 Cells
-
Ghil SH, Suh-Kim HY
- KMID: 2030748
- Korean J Anat.
- 2002 Apr;35(2):125-131.
Heterotrimeric G proteins mediate signals generated by neurotransmitters and hormones. Among G proteins, Go is found in a large quantity in brain and growth cone membranes of neurons. In spite... -
- CITED
-
- Close
- SHARE
-
- Close
