- Is Thalidomide Safe and Effective for the Inhibition of Neointima Hyperplasia?
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Kim W, Jeong MH
- KMID: 2294358
- Korean Circ J.
- 2004 Apr;34(4):343-345.
- doi: 10.4070/kcj.2004.34.4.343
No abstract available. -
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- Formation and Transformation of Neointima after Drug-eluting Stent Implantation: Insights from Optical Coherence Tomographic Studies
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Lee SY, Hong MK, Jang Y
- KMID: 2396474
- Korean Circ J.
- 2017 Nov;47(6):823-832.
- doi: 10.4070/kcj.2017.0157
After coronary stent implantation, neointima formation resembles the wound healing process as it involves the sequential processes of inflammation, granulation, and remodeling. Because antiproliferative drugs and polymers of drug-eluting stents... -
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- Optical Coherence Tomographic Observation of Morphological Features of Neointimal Tissue after Drug-Eluting Stent Implantation
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Lee SY, Shin DH, Kim JS, Kim BK, Ko YG, Choi D, Jang Y, Hong MK
- KMID: 2130818
- Yonsei Med J.
- 2014 Jul;55(4):944-952.
- doi: 10.3349/ymj.2014.55.4.944
PURPOSE: The impacts of different time courses and the degree of neointimal growth on neointimal morphology have not yet been sufficiently investigated. Therefore, we evaluated the morphological features of neointimal... -
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- A Case of Neointimal Calcification in a Drug-Eluting Stent
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Yang YJ, Shim J, Kim JS, Ko YG, Choi D, Jang Y, Hong MK
- KMID: 2263951
- Korean J Med.
- 2011 Jul;81(1):98-101.
Neointimal hyperplasia is the main mechanism of stent restenosis. Therefore, drug-eluting stents have replaced bare metal stents because there is less neointima and scar formation. Recently, some cases of stent... -
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- The Effects of Macrophage on Neointimal Formation after Balloon or Stent Injury in Hypercholesterolemic Rabbits
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Rhee MY, Kim YK, Lee MY, Park BE, Kim DW, Cho MC
- KMID: 2297958
- Korean Circ J.
- 2005 Nov;35(11):801-811.
- doi: 10.4070/kcj.2005.35.11.801
BACKGROUND AND OBJECTIVES: The present study investigated differences in the effects of macrophages between neointimal formation after balloon (BI) and that after stent injury (SI) in hypercholesterolemic rabbits. We also... -
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- The Effect of L-arginine on Neointima Formation in a Rat Vascular Injury Model
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Jeon DS, Kim JH, Yoo KD, Chae JS, Hong SJ, Choi KB
- KMID: 1894777
- Korean Circ J.
- 1997 Dec;27(12):1350-1360.
- doi: 10.4070/kcj.1997.27.12.1350
BACKGROUND: The inhibitory effects of nitric oxide(NO) on platelet adhesion and vascular smooth muscle cell(VSMC) proliferation may have a possible role inhibiting development of neointima following balloon catheter induced injury.... -
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- A Slight Variation in the Age of Rats Commonly used as a Carotid Artery Injury Model Results in a Large Difference in Neointima Formation
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Kwon JS, Park NK, Jeong IH, Kim YK, Bae JH, Hwang KK, Kim DW, Cho MC
- KMID: 1859085
- Korean Circ J.
- 2007 Feb;37(2):78-83.
- doi: 10.4070/kcj.2007.37.2.78
BACKGROUND AND OBJECTIVES: The degree of neointima formation after infliction of a carotid artery balloon injury in rats varies greatly depending on the sex, age, species and operational method. Strong... -
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- The Effects of Pioglitazone in Reducing Atherosclerosis Progression and Neointima Volume in Type 2 Diabetic Patients: Prospective Randomized Study With Volumetric Intravascular Ultrasonography Analysis
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You SH, Kim BS, Hong SJ, Ahn CM, Lim DS
- KMID: 2225160
- Korean Circ J.
- 2010 Dec;40(12):625-631.
- doi: 10.4070/kcj.2010.40.12.625
BACKGROUND AND OBJECTIVES: Pioglitazone has been known for its anti-atherogenic effects. We compared the effects of pioglitazone in reducing atherosclerosis progression and neointima volume in type 2 diabetic patients. SUBJECTS AND... -
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- Inhibition of TGF-beta by Gene Delivery does not Alter the Neointima Area, but Enhances Inflammation in In-Stent Stenosis of Pig Coronary Arteries
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Chung IM
- KMID: 2227174
- Korean Circ J.
- 2004 Nov;34(11):1022-1032.
- doi: 10.4070/kcj.2004.34.11.1022
BACKGROUND: We have shown that extracellular matrix (ECM) rather than cell proliferation contributes to in-stent restenosis. Transforming growth factor-beta (TGF-beta), a positive regulator of ECM deposition by vascular cells, may... -
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- A Newly Formed and Ruptured Atheromatous Plaque within Neointima after Drug-Eluting Stent Implantation: 2-Year Follow-Up Intravascular Ultrasound and Optical Coherence Tomography Studies
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Oh CM, Moon J, Yu HT, Jang JY, Kim JS, Ko YG, Choi D, Jang Y, Hong MK
- KMID: 1058827
- Yonsei Med J.
- 2011 Nov;52(6):1028-1030.
- doi: 10.3349/ymj.2011.52.6.1028
Late stent thrombosis (LST) which is a life threatening complication has emerged as a serious problem of drug-eluting stents (DES). Several studies have suggested that incomplete neointimal coverage of stent... -
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- A Case of In-Stent Neointimal Plaque Rupture 10 Years After Bare Metal Stent Implantation: Intravascular Ultrasound and Optical Coherence Tomographic Findings
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Yoon HJ, Hur SH, Kim SK, Kim H, Park HS, Cho YK, Nam CW, Kim YN, Kim KB
- KMID: 2225076
- Korean Circ J.
- 2011 Nov;41(11):671-673.
- doi: 10.4070/kcj.2011.41.11.671
Neointimal hyperplasia mainly develops within several months of coronary stent deployment, after which it stabilizes. Although it was widely accepted, particularly during the bare-metal stent (BMS) era, that in-stent restenosis... -
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- An Experimental Study on the Influence of New Spiral Stent(Hanaro) on the Vascular Structures
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Lim MK, Park JH, Chung JW, Jeong YK, Kook MC, Seo JW
- KMID: 2347016
- J Korean Radiol Soc.
- 1996 Jun;34(6):745-756.
PURPOSE: The purpose of this study was to evaluate basic experimental data for the clinical application of a self-expandable stainless steel intravascular Hanaro spiral stent. MATERIALS AND METHODS: For evaluation of... -
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- Tumor Suppressor Serine/Threonine Kinase LKB1 Expression, Not Kinase Activity, Increased in the Vascular Smooth Muscle Cells and Neointima in the Rat Carotid Artery Injury Model
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Jeong JO, Kim JH, Ahn KT, Park HS, Jang WI, Park JH, Lee JH, Choi SW, Kim JM, Seong IW
- KMID: 1826173
- Korean Circ J.
- 2010 Nov;40(11):552-557.
- doi: 10.4070/kcj.2010.40.11.552
BACKGROUND AND OBJECTIVES: Vascular smooth muscle cell (VSMC) proliferation is responsible for the restenosis of previously inserted coronary stents. Angiotensin II (Ang II) is known to regulate VSMC proliferation. LKB1,... -
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- The change in phospholipase C-gamma1 expression following balloon injury to the rat carotid artery
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Lim SH, Heo YS, Kim HJ, Lee WS, Ahn JH, Song YB, Kim SW, Kim TH, Kim CJ, Ryu WS, Ryoo UH
- KMID: 2253148
- Korean J Med.
- 2001 Mar;60(3):234-241.
BACKGROUND: While inositol phospholipid-specific phospholipase C (PLC) plays a central role in signal transduction pathways, little is known about its role in the vascular response to injury. Recent studies have... -
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- The Histologic Study of the Neoendothelialization of Polytetrafluoroethylene as an Arterial Substitute in Rabbit
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Lee KS, Kang KH, Kyon KH
- KMID: 2105495
- J Korean Orthop Assoc.
- 1998 Dec;33(7):1909-1920.
The purpose of this study was to investigate the patency rates and the histologic findings of neoen- dothelialization according to the length of implanted polytetrafluoroethylene (PTFE) with an internal diameter... -
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- Bortezomib Reduces Neointimal Hyperplasia in a Rat Carotid Artery Injury Model
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Kim KS, Kim SY, Choi JH, Joo SJ, Kim DW, Cho MC
- KMID: 2224814
- Korean Circ J.
- 2013 Sep;43(9):592-599.
- doi: 10.4070/kcj.2013.43.9.592
BACKGROUND AND OBJECTIVES: The ubiquitin-proteasome system is the major intracellular protein degradation pathway in the eukaryotic cells. Bortezomib inhibits 26S proteasome-induced I-kappaBalpha degradation and suppresses nuclear factor-kappa B (NF-kappaB) activation.... -
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- Inhibition of Neointima Formation by Anti-Vascular Endothelial Growth Factor and Receptor-1 Peptides in a Balloon-Injured Rat Carotid Artery
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Lee JM, Moon KW, Yoo KD, Her SH, Yoon HJ, Jin SW, Jeon DS, Youn HJ, Chung WS, Seung KB, Kim CM, Kim JH, Choi KB, Hong SJ
- KMID: 2227048
- Korean Circ J.
- 2007 Oct;37(10):475-482.
- doi: 10.4070/kcj.2007.37.10.475
BACKGROUND AND OBJECTIVES: Vascular endothelial growth factor (VEGF) is a potent endothelial cell-specific mitogen. This study was undertaken to test the hypothesis that the neointima hyperplasia induced by a balloon... -
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- The Role of Extracellular Matrix within the Neointima in A Porcine Coronary Stent Restenosis Model
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Park OY, Jeong MH, Kim JH, Kim W, Lee SH, Hong YJ, Kim JH, Park WS, Ahn YK, Park JT, Cho JG, Park JC, Kang JC
- KMID: 2029614
- Korean Circ J.
- 2003 Feb;33(2):121-129.
- doi: 10.4070/kcj.2003.33.2.121
BACKGROUND AND OBJECTIVES: Coronary stent restenosis remains a major limitation to percutaneous coronary intervention. The most important mechanism of coronary stent restenosis is neointimal hyperplasia (NIH). In addition to neointimal... -
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- Experimental Study of the Histologic Findings of the Neoendothelialization according to Length of Polytetrafluoroethylene in Rabbit
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Lee KS, Kang KH, Kyon KH
- KMID: 2199179
- J Korean Orthop Res Soc.
- 1998 Oct;1(2):174-187.
The purpose of this study was to investigate the patency rates and the histologic findings of neoendothelialization according to the length of implanted polytetrafluoroethylene (PTFE) with an internal diameter of... -
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- Oral Everolimus Reduces Adventitial Cell Activation and Neointima Formation in Balloon-Injured Rat Carotid Artery
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Moon KW, Lee JM, Chang K, Yoo KD, Jeon DS, Youn HJ, Chung WS, Lee MY, Kim JJ, Seung KB, Kim CM, Hong SJ
- KMID: 2227194
- Korean Circ J.
- 2004 Oct;34(10):983-991.
- doi: 10.4070/kcj.2004.34.10.983
BACKGROUND AND OBJECTIVES: Previous studies suggest that phenotypic conversion, proliferation and migration of adventitial fibroblasts after balloon injury have an important role in neointimal formation and vascular remodeling. The present... -
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