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Naltrexone-associated Visual Hallucinations: A Case Report

Lee DB, Woo YS, Bahk WM

Naltrexone is a competitive antagonist of μ, δ, and κ opioid receptors. Naltrexone has been investigated for use an as anti-obesity agent in both the general population and in patients...
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Effect of Combined Administration of Acamprosate and Naltrexone on Alcohol Intake in C57BL/6 Mice

Kim SG, Han BD, Park JM, Kim MJ

  • KMID: 2340608
  • J Korean Neuropsychiatr Assoc.
  • 2001 Sep;40(5):981-990.
OBJECTIVES: For the relapse prevention in alcohol dependence, a lot of studies suggested that combined administration of two or more drugs which have different mechanism of action is more effective...
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A Case of Prurigo Nodularis Treated with Narrow-band UVB and Naltrexone

Park HS, Lee SY, You CE, Park MY, Son SJ

  • KMID: 2302511
  • Korean J Dermatol.
  • 2005 Aug;43(8):1113-1115.
Prurigo nodularis is a distressing, chronic disease, which is considered to be very resistant to therapy. Treatment choice is quite limited. Among them, opiate antagonist and phototherapy have been used...
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Effect of Naltrexone on Acute Alcohol Response in Social Drinker

Kim JH, Kim SG, Shin SH, Park JM, Kim MJ

  • KMID: 2341046
  • J Korean Neuropsychiatr Assoc.
  • 2004 Nov;43(6):689-696.
OBJECTIVES: We investigated the effects of naltrexone on acute alcohol response, stimulant and sedative, in healthy social drinkers using two doses of alcohol intake. METHODS : Twenty four healthy male medical...
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A Case Report: Irbesartan and Naltrexone Treatment of Polydipsia in a Patient with Schizophrenia

Dong HS, Kim SH, Park SY

Polydipsia in schizophrenic patients is not uncommon, but a frequently underdiagnosed condition. The etiology of polydipsia remains unclear, and its complications can be life-threatening, while often being difficult to manage...
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Clinical Efficacy and Safety of Naltrexone Combination Therapy in Older Patients with Severe Pruritus

Lee J, Shin JU, Noh S, Park CO, Lee KH

BACKGROUND: Severe pruritus is a challenging condition, and it is more difficult to deal with in older patients due to their limitations in taking oral medication because of underlying diseases,...
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Blockade by Naloxone and Naltrexone of the TRH-induced Stimulation of Colonic Transit in the Rabbit

Pae YS

Thyrotropin releasing hormore(TRH) administered intracerebroventricularly (i.c.v) in microgram quantities to anesthetized rabbits, produces marked stimulation of colonic motility, transit and fluid accumulation. These effects depend on an intact vagal system....
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Effect of Naltrexone and Olanzapine on Alcohol Consumption of C57BL-6 Type Rats

Yun KB, Kwon YJ, Han SW

  • KMID: 2340657
  • J Korean Neuropsychiatr Assoc.
  • 2002 Mar;41(2):246-253.
OBJECTIVE: This study compared the effects of opioids antagonist naltrexone and serotonin-dopamine recepter antagonist olanzapine on the reduction of alcohol consumption level of alcohol intake reinforced C57BL-6 type rat. METHODS: Small...
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Pharmacological and Behavioral Approaches in the Treatment of Pathological Gambling

Shin YC

  • KMID: 1985332
  • Korean J Psychopharmacol.
  • 2001 Dec;12(4):287-293.
Pathological gambling is classified as impulse control disorder in DSM-IV, but in clinical aspects it is similar with addictive disorder. Hence some pharmacological agents which are used to addictive disorders...
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Alcohol Urge and Plasma beta-endorphin Change after Alcohol Challenge in Naltrexone Pretreated Social Drinker

Kim EH, Sohn IK, Lee YS, Na C

  • KMID: 2340477
  • J Korean Neuropsychiatr Assoc.
  • 2000 Jul;39(4):754-765.
OBJECTIVES: The present study was performed to evaluate whether naltrexone treatment are effectively lowering the urge of alcohol drinking, and to investigate the its mechanism of action. METHODS: 15 healthy male...
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The Impact of Hot Food Preferences on Naltrexone's Effects on Subjective Acute Responses to Alcohol in Social Drinkers

Jeong HJ, Kim SG, Kim JH, Park SH, Kang CJ

  • KMID: 2341357
  • J Korean Neuropsychiatr Assoc.
  • 2007 Nov;46(6):566-572.
OBJECTIVES: Both capsaicin, a pungent substance of hot food, and alcohol, are known to affect central opioid activity. The purpose of this study was to investigate the difference in the...
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Difference of the Naltrexone's Effects in Social Drinkers by Spicy Food Preference

Lee JS, Kim SG, Jeong HJ, Kim JH, Yang YH, Jung WY

The purpose of this study was to investigate the differences in subjective acute effects of alcohol and naltrexone among those who prefer spicy food to varying degrees. Acute biphasic alcohol...
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Understanding the Mechanism of Action and Clinical Implications of Anti-Obesity Drugs Recently Approved in Korea

Kim KK

The Korean Ministry of Food and Drug Safety has approved three anti-obesity drugs for long-term management in the past decade. In addition, since 2019, bariatric surgery has been financially supported...
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Changes of Smoking Urge and Endogenous Opioids, Prolactin, ACTH, Cortisol Levels in Nicotine Dependents with Naltrexone Pretreatment

Sohn IK, Lee YS, Na C

  • KMID: 1636033
  • J Korean Neuropsychiatr Assoc.
  • 2003 Jul;42(4):476-484.
OBJECTIVES: There is a controversy on the mechanism of nicotine dependence. Some suggest that the negative reinforcement such as withdrawal symptoms plays an important role, but others suggest that the...
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Drinking in the Context of Health-Sustaining Habits

Park BK

The comprehensive medical care delivered by family physicians should involve education and practice of health-sustaining habits such as diet, exercise, relaxation etc. as well as drug prescription. Among those, problem...
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KASL Clinical Practice Guidelines: Management of Alcoholic Liver Disease

The Korean Association for the Study of the Liver (KASL)

No abstract available.
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Pharmacotherapy for Alcohol Dependence: Anticraving Medications for Relapse Prevention

Jung YC, Namkoong K

Alcohol dependence is a chronic disorder that results from a variety of genetic, psychosocial, and environmental factors. Relapse prevention for alcohol dependence has traditionally involved psychosocial and psychotherapeutic interventions. Pharmacotherapy,...
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Psychotrophic Drug Therapy of the Sexual Offenders or Paraphilia

Kang SH, Lee JW, Lim MH

  • KMID: 2287454
  • Korean J Psychopharmacol.
  • 2013 Apr;24(2):59-68.
Sexual violence crime causes severe trauma to victim's family as well as the victim, and its aftereffect which is hard to be healed can last for the entire lifetime. And...
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Neuropeptides in Clinical Psychiatric Research : Endorphins and Cholecystokinins

Kim YH, Shin JC

  • KMID: 1834620
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):34-45.
We provide the reader with a brief introduction to the neurobiology of neuropeptides. Several comprehensive reviews of the distribution and neurochemical. neurophysiological. neuropharmacological and behavioral effects of the major neuropeptides...
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Naltrexone influences protein kinase C epsilon and integrin alpha7 activity in SH-SY5Y neuroblastoma cells

Oh DY, Jung KH, Yang BH, Lee JS, Choi IG, Chai YG

  • KMID: 1105282
  • Exp Mol Med.
  • 2006 Feb;38(1):100-106.
Alcohol influences the neuroadaptation of brain cells where receptors and enzymes like protein kinase C (PKC) exist. Naltrexone acts on opioid receptors. However, other mechanisms of action remain unknown. We...
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