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Molecular Epidemiology of Nalidixic Acid Resistance in Shigella sonnei Isolates

Seol SY, Do YK, Jeong YS, Kang HY, Lee JC, Lee YC, Cho DT, Jung TH

  • KMID: 2168478
  • J Bacteriol Virol.
  • 2005 Mar;35(1):23-30.
Twenty-six nalidixic acid-resistant Shigella sonnei strains isolated from 1982 to 2001 and 56 nalidixic acid-resistant mutants induced by quinolone drugs from susceptible wild strains were analyzed by sequencing the gyrA...
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Prevalence and Mechanisms of Low Level Quinolone Resistance among Non-Typhoidal Salmonella Isolates from Human and poultry/Livestock in Korea: Usefulness of Nalidixic Acid Resistance Test

Hwang IS, Song JY, Kim WJ, Jeong HW, Kim MS, Cheong HJ

BACKGROUND: Non-typhoidal Salmonella (NTS) are important commensal microorganisms. We intended to investigate the prevalence and mechanisms of nalidixic acid resistance among NTS isolated from human and poultry/livestock. METHODS: A total of...
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A Case of Typhoid Fever to Failed Ciprofloxacin, Infected in Korea

Lee KS, Lee HY, Jeon EJ, Chung JW

Typhoid fever caused by Salmonella enterica serovar Typhi (S. typhi) and usually ciprofloxacin is first used for treatment. However, the incidence of fluoroquinolone resistance or reduced susceptibility in S. typhi...
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A Case of Acute Osteomyelitis of the Femur Caused by Nalidixic-Acid-Resistant Salmonella enteritidis

Na SK, Kim TJ, Lee JA, Lee SS, Koh SH, Kim TY, Kim HS

Infection with nontyphoidal Salmonella most often results in self-limited acute gastroenteritis. However, occasionally it causes bacteremia and localized infection requiring antibiotic treatment. A third-generation cephalosporin or fluoroquinolone is often the...
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The Use of Fluoroquinolones in Children: Recent Advances

Choi KM

Fluoroquinolones have been widely used since the development of nalidixic acid because of the excellent spectrum of activity, superior tissue penetration, and convenient route of administration. Despite such advantages, the...
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Three cases of ciprofloxacin treatment failure in imported typhoid fever

Kim DB, Kim SH, Oh SJ, Kim DK, Choi SM, Kim M, Shin WS

  • KMID: 2258447
  • Korean J Med.
  • 2009 Sep;77(3):377-381.
Recently, the role of ciprofloxacin in the empirical treatment of typhoid fever has been limited with the increased incidence of nalidixic acid-resistant Salmonella enterica serovar Typhi in South-central and Southeast...
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The Clinical Effect of Oxolinic Acid on Genitourinary Tract Infection

Song SI, Lee JB

  • KMID: 1677906
  • Korean J Urol.
  • 1978 Jun;19(3):241-245.
Oxolinic acid is a weak-organic acid which developed recently from Nalidixic acid. Author reports a clinical observation about the effect of oxolinic acid on patients of genito-urinary tract infection, who...
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Co-infection with Giardia lamblia and Salmonella species after travel abroad

Park HW, Hong KW, Kwon HL, Kim MK, Kim WJ, Kim JS, Eom JS

  • KMID: 2081687
  • Korean J Med.
  • 2009 Apr;76(Suppl 1):S211-S215.
As many Koreans now travel abroad, they are at increased risk for a variety of infectious diseases that are endemic to developing countries in the tropics and subtropics. We report...
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An Imported Case of Typhoid Fever Refractory to Ciprofloxacin Treatment

Park JE, Chung MH, Lee JS, Kim JJ

  • KMID: 2054332
  • Infect Chemother.
  • 2007 Feb;39(1):46-49.
Salmonella enterica serovar Typhi infection is widely prevalent in developing countries; its treatment has been complicated by the emergence of resistance to antimicrobial agents. Fluoroquinolones are orally administered antimicrobials effective...
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A Case of Renal and Liver Abscesses Caused by Nalidixic Acid-Resistant Salmonella typhi

Lim SY, Kim HJ, Han JS, Kang DH, Lee JA, Lee SS, Kim MJ

  • KMID: 2082473
  • Korean J Med.
  • 2013 Apr;84(4):608-612.
Prompt antibiotic treatment reduces the incidence of complications such as liver abscesses, pyelonephritis, and osteomyelitis in patients with typhoid fever. Renal or liver abscesses are especially rare in patients without...
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Antimicrobial Resistance in Escherichia coli Isolated from Healthy Volunteers of the Community

Lee JM, Hwang KW, Jegal S

  • KMID: 2224735
  • Korean J Clin Microbiol.
  • 2007 Apr;10(1):32-36.
BACKGROUND: We monitored the prevalence of antimicrobial resistance and the pattern of multiple drug resistance in Escherichia coli isolated from healthy people in the community. METHODS: We performed antimicrobial susceptibility testing...
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Species Identification of the Genus Aeromonas Isolated from Freshwater Fish Culture-ponds and Seawater in Korea and Their Antibiotic Resistance Patterns

Lee HK, Kang DR

  • KMID: 2146900
  • J Korean Soc Microbiol.
  • 1999 Aug;34(4):393-400.
Some species of mesophilic bacteria in the genus Aeromonas were isolated from a snakehead (Channa argus) culture-pond in the Myung-Ji area, a freshwater culture-pond in Pukyung National University, and seawater...
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Medium Supplementation and Atmospheric Condition for Growth of Campylobacter pylori isolated from gastric biopsy tissue

Jeon CH, Bae EK, Kim KD, Hong SI, Kim CS

Experiments were conducted to define the optimal constituents of culture medium and atmospheric condition for growth of Campylobacter pylori. Two clinical isolates were streaked onto various media, incubated in two...
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Time Kill Studies of Antibiotics against a Nalidixic Acid Resistant Salmonella enterica serotype Typhi

Kim DM, Yun NR, Chung JH, Ryu HH

BACKGROUND: We recently encountered a case of typhoid fever in a patient who visited us after travelling India. The patient received ciprofloxacin therapy, but developed typhoid pneumonia and typhoid hepatitis,...
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Evaluation of the Phototoxic Potential of Some Quinolone Antibiotics

Cho YH, Kim TH, Park HB, Park CK, Park KM

  • KMID: 2230754
  • Korean J Dermatol.
  • 1995 Dec;33(6):1021-1028.
BACKGROUND: The photsensitizing effect of quinolones has been recognized since their introdulation as an antibacterial agents. Recently several new second eneration antibacterial agents of this pharmacological class have become available...
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Biodegradable Polymer Releasing Antibiotic Developed for Drainage Catheter of Cerebrospinal Fluid:In Vitro Results

Han SY, Yoon SH, Cho KH, Cho HJ, An JH, Ra YS

The authors developed a biodegradable polymer that releases an antibiotic (nalidixic acid) slowly and continuously, for prevention of catheter-induced infection during drainage of cerebrospinal fluid. We investigated the in vitro...
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A case of gastrointestinal Kaposi sarcoma in a patient with AIDS

Chung DW, Chang HH, Hwang HY, Kim HI, Park GY, Kim SW, Lee JM

  • KMID: 2258446
  • Korean J Med.
  • 2009 Sep;77(3):371-375.
Kaposi sarcoma in acquired immunodeficiency syndrome (AIDS) is rarely seen in Korea and the incidence has declined in the era of highly active antiretroviral therapy (HAART). Visceral involvement in patients...
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Characterization of Salmonella spp. Clinical Isolates in Gyeongsangbuk-do Province, 2012 to 2013

Kweon OG, Kim JS, Kim GO, Lee CI, Jeong KH, Kim J

BACKGROUND: Extended-spectrum cephalosporins and fluoroquinolones are important antimicrobials for treating invasive salmonellosis, and emerging resistance to these antimicrobials is of paramount concern. METHODS: A total of 30 Salmonella spp. clinical isolates...
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Antibiotic Resistance of Multiple-Antibiotic-Resistance (Mar) Mutants of Escherichia coli K-12

Park BT

  • KMID: 2099287
  • J Korean Soc Microbiol.
  • 1998 Apr;33(2):195-203.
Multiple-antibiotic-resistance (Mar) mutants were prepared from the wild-type Escherichia coli K-12 MC4100 or W3110, were analyzed for the antibiotic resistance by minimal inhibitory concentration (MIC), and compared with their isogenic...
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Antibiotic Resistance Patterns and Serotypes of Salmonella spp. Isolated at Jeollanam-do in Korea

Yoon KB, Song BJ, Shin MY, Lim HC, Yoon YH, Jeon DY, Ha H, Yang SI, Kim JB

OBJECTIVES: Few long-term studies have been conducted on the serotype and antibiotic resistance patterns of Salmonella speices (spp.) The aim of this study was to determine the serotypes and antibiotic...
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