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A Case of Polyagglutination due to T Activation

Kim HO, Kim JJ, Choi SS

  • KMID: 2253863
  • Korean J Blood Transfus.
  • 1996 Dec;7(2):263-268.
Red blood cells that agglutinate with most normal adult sera but never with own sera are termed polyagglutinable and can be separated by patterns of lectin reactivity into various types....
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A Case of GNE Myopathy Presenting a Rapid Deterioration during Pregnancy

Sim JE, Hong JM, Suh GI, Cho H, Park KS, Sohn EH, Choi YC

BACKGROUND: GNE myopathy is characterized by early-adult-onset distal myopathy sparing quadriceps caused by mutations in the GNE gene encoding UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, an enzyme in the sialic-acid synthesis pathway. CASE REPORT:...
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Binding of the Streptococcus gordonii Surface Glycoprotein Hsa to alpha(2-3) Linked Sialic Acid Residues on Fibronectin

Jang AY, Lin S, Lim S, Kim DH, Seo HS

The binding of microorganisms to platelets is a critical step in the development of infective endocarditis. In Streptococcus gordonii, this binding is mediated in part by serine-rich repeat proteins, which...
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Anti-Helicobacter pylori activity of crude N-acetylneuraminic acid isolated from glycomacropeptide of whey

Kim DJ, Kang MJ, Choi JA, Na DS, Kim JB, Na CS, Park JH

Helicobacter pylori colonizes the gastric mucosa of about half of the world's population, causing chronic gastritis and gastric cancer. An increasing emergence of antibiotic-resistant H. pylori arouses demand on alternative...
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Levels of Salivary Sialic Acid in Children with Autism Spectrum Disorder; Could It Be Related to Stereotypes and Hyperactivity?

Demirci E, Guler Y, Ozmen S, Canpolat M, Kumandas S

OBJECTIVE: Sialic acid (Sia) is an essential nutrient for brain development, learning, memory and cognition and plays a role in neurodevelopment of infants. The aim of this study was to...
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Expression of the ED3 Antigen and its Upregulation after Cyclophosphamide Treatment on Basal Epithelial Cells of Rat Stratified Squamous Epithelium

Choi HU, Lee SK, Shim NR, Lee HW, Baek SY, Kim JB, Kim BS, Yoon S

  • KMID: 1894512
  • Korean J Anat.
  • 2003 Feb;36(1):1-10.
Sialoadhesin (Sn) expression has been demonstrated on murine and rat macrophages in lymphatic organs and is recognized by the monoclonal antibody (mAb) ED3 in the rat. Sialoadhesin (Siglec-1), the ED3...
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Expression of Sialic Acids according to the Differentiation of Cultured Human Nasal Epithelial Cells

Suh KS, Kim KS, Choi JW, Yoon JH, Lee JG

  • KMID: 2074280
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 May;40(5):663-669.
BACKGROUND: Sialic acid residues are known to play a key role in the normal function of the glycoconjugates. Recently, with the development of specific sialic acid binding lectins such as...
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Novel Mutation of the GNE Gene Presenting Atypical Mild Clinical Feature: A Korean Case Report

Choi YA, Park SH, Yi Y, Kim K

Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (GNE) myopathy is caused by mutations in GNE, a key enzyme in sialic acid biosynthesis. Here, we reported a case of GNE that presented with atypical mild...
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Functions of Siglecs in Allergic Inflammation

Lee HH

  • KMID: 2051628
  • Pediatr Allergy Respir Dis.
  • 2006 Sep;16(3):197-205.
Siglecs are sialic acid binding Ig-like lectins, subset of the immunoglobulin superfamily. They are characterized by a homologous N-terminal V-set Ig-like domain and C2 set Ig-like domains. N-terminal domains...
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Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking

Sahoo M, Jena L, Rath SN, Kumar S

The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for...
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Serum Levels of Sialic acid, CRP, and TNF-a in Type 2 Diabetin Patients with Syndrome X

Choi DS, Kim SJ, Paek SH, Choi KM, Kim NH, Oh JH, Kim YH

  • KMID: 2063343
  • J Korean Diabetes Assoc.
  • 1999 Jun;23(3):307-314.
diabetic nephropathy and macro- vascular complications. Thus it is possible to conBACKGROUND: Type 2 diabetes is associated with increased blood concentrations of acute phase reactants including; sialic acid, ai-acid glycoprotein,...
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Classification of the Carbohydrate using pectin Binding Characteristics and PAS Reaction in Human Gingiva

Park BS, Kim JJ, Kim JB, Kim JH, Yoon S, Kim DH

This study was performed in order to recognize the identifications of the glycoproteins containing oligosaccharides in human gingiva. After made paraffin sections of human gingiva at 4µm, the sections were...
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Neuraminidase Inhibitors from the Fruiting Body of Glaziella splendens

Kim JY, Woo EE, Ha LS, Ki DW, Lee IK, Yun BS

Neuraminidase (NA) cleaves the glycosidic bond linkages of sialic acids to release the mature virions from infected cells and has been an attractive therapeutic target for anti-influenza agents. In our...
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Hematopoietic effect of deer antler extract fermented by Bacillus subtilis on murine marrow cells

Park Y, Choi HS, Lee HS, Suh HJ

BACKGROUND/OBJECTIVES: We examined the chemical composition and the effect of fermented deer antler on hematopoietic factors in bone marrow cells. MATERIALS/METHODS: For the preparation of fermented deer antler extract (FAB), fermentation...
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Biological Property of Recombinant Hemagglutinin-Neuraminidase Protein of Avian Paramyxovirus Type 6 Expressed by Recombinant Baculovirus

Kim JY, Lee HJ, Kye SJ, Kim S, Seul HJ, Kim SE, Lee HS, Jung SC, Choi KS

Hemagglutination inhibition (HI) test employing whole virus antigen is a prescribed serological test for serotyping, diagnosis and surveillance for avian paramyxoviruses (APMVs). For use as alternative to the virus antigen,...
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Anti-bacterial effects of enzymatically-isolated sialic acid from glycomacropeptide in a Helicobacter pylori-infected murine model

Noh HJ, Koh HB, Kim HK, Cho HH, Lee J

BACKGROUND/OBJECTIVES: Helicobacter pylori (H. pylori) colonization of the stomach mucosa and duodenum is the major cause of acute and chronic gastroduodenal pathology in humans. Efforts to find effective anti-bacterial strategies...
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Tissue distribution of sialic acid-linked influenza virus receptors in beagle dogs

Ning ZY, Wu XT, Cheng YF, Qi WB, An YF, Wang H, Zhang GH, Li SJ

Reports of influenza A virus infections in dogs has received considerable attention from veterinarians, virologists, and epidemiologists. Interaction between influenza viral hemagglutinin and cell oligosaccharides containing sialic acid residues results...
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Correlation of C-reactive Protein with Components of Metabolic Syndrome in Elderly Korean Women with Normal or Impaired Glucose Tolerance

Kwon SB, Choi KM, Park SY, Yoo HJ, Ryu OH, Park SS, Kim HY, Lee KW, Seo JA, Oh JH, Kim SG, Kim NH, Baik SH, Choi DS

  • KMID: 2008171
  • J Korean Diabetes Assoc.
  • 2004 Oct;28(5):432-440.
BACKGROUND: Previous studies have reported that type 2 diabetes is associated with the increased blood concentrations of markers for the acute phase response, such as C-reactive protein (CRP), serum sialic...
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In vivo morphological and antigenic characteristics of Photobacterium damselae subsp. piscicida

Jung TS, Thompson K, Volpatti D, Galeotti M, Adams A

The present study was conducted to examine the morphology and antigenicity of Photobacterium damselae subsp. piscicida by culturing the bacterium in vivo in the peritoneal cavity of sea bass (Dicentrarchus...
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