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Mechanisms of Muscle Wasting in Patients with Sepsis

Lee GD, Kim HC

Muscle wasting is commonly seen in patients with sepsis as a consequence of the catabolic response in skeletal muscle. Muscle wasting can occur in cases that have an imbalance between...
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Diagnostic Significance of Immunohistochemical Staining in Muscular Dystrophy

Kim DS

  • KMID: 1957670
  • J Korean Neurol Assoc.
  • 2006 Feb;24(1):1-13.
Muscular dystrophy (MD) is a heterogeneous group of inherited muscle disorders caused by the mutations of different genes encoding muscle proteins, and it is now classified according to the results...
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Recent Advances in Skeletal Muscle Stem Cells for Duchenne Muscular Dystrophy Treatment

Yang JY, Jeong J

Muscle stem cells, which are known as satellite cells have heterogeneous components of committed myogenic progenitors, non-committed satellite cells, and mesenchymal stem cells. This distinguishing organization of self-renewal and differentiation...
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A Case of Polymyositis associated with Hepatitis B infection

Sin SK, Joo IS, Han BI, Hong JM, Joo SY, Kim JH

  • KMID: 2342982
  • J Korean Neurol Assoc.
  • 2002 May;20(3):315-317.
Polymyositis(PM) is one of idiopathic inflammatory myopathy, characterized by proximal muscle weakness, myalgia and muscle enzyme elevation. Currently the main pathogenesis is well documented, the cell-mediated immunity. We experienced a...
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Acute Myositis of the Tibialis Anterior Muscle after Performance of 108 Prostrations

Lee SY, Kwon MJ, Seo YI, Kim HA

Exercise-induced muscle damage (EIMD) can be caused by novel or unaccustomed exercise resulting in a temporary decrease in muscle function, increased muscle soreness and swelling, and an increase in muscle...
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A case of thyrotoxic periodic paralysis associated with rhabdomyolysis

Kweon KH, Lee CH, Choi KS, Baek SH, Lee MS, Park BH, Cho CG

  • KMID: 1984906
  • Korean J Med.
  • 2004 Feb;66(2):230-233.
Hyperthyroidism has been associated with changes in muscle function such as thyrotoxic myopathy, thyrotoxic periodic paralysis and thyroid opthalomopathy, but rarely rhabdomyolysis. Usually serum creatinine kinase is either normal or...
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Proteomic Changes in Rat Gastrocnemius Muscle After Botulinum Toxin A Injection

Han N, Kim HD, Eom MJ, You JM, Han J, Kim HK, Kang MS

OBJECTIVE: To observe the changes in protein expression induced by botulinum toxin A (BoNT-A) injection and to characterize the molecular and cellular action of mechanisms of BoNT-A injection on skeletal...
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Short-term protein intake increases fractional synthesis rate of muscle protein in the elderly: meta-analysis

Gweon HS, Sung HJ, Lee DH

  • KMID: 2313469
  • Nutr Res Pract.
  • 2010 Oct;4(5):375-382.
The precise effects of protein intake on fractional synthesis rate (FSR) of muscle protein are still under debate. The sample size of these studies was small and the conclusions in...
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Modulation of transglutaminase expression in rat skeletal muscle by induction of atrophy and endurance training

Park SC, Kim WH, Lee MC, Seong SC, Song KY, Choe MA

The persistence of muscle fiber number regardless of size reduction in muscle atrophy has not yet been fully explained. For the mechanism inherent in skeletal muscle tissues for preventing cellular...
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Docosahexaenoic acid-mediated protein aggregates may reduce proteasome activity and delay myotube degradation during muscle atrophy in vitro

Shin SK, Kim JH, Lee JH, Son YH, Lee MW, Kim HJ, Noh SA, Kim KP, Kim IG, Lee MJ

Proteasomes are the primary degradation machinery for oxidatively damaged proteins that compose a class of misfolded protein substrates. Cellular levels of reactive oxygen species increase with age and this cellular...
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Role of IL-15 in Sepsis-Induced Skeletal Muscle Atrophy and Proteolysis

Kim HC, Cho HY, Hah YS

BACKGROUND: Muscle wasting in sepsis is associated with increased proteolysis. Interleukin-15 (IL-15) has been characterized as an anabolic factor for skeletal muscles. Our study aims to investigate the role of...
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Viability of Clonorchis sinensis Metacercaria according to the Food-processing Methods

Cho YJ, Chu JP, Rim HJ, Hwang SK

  • KMID: 2082959
  • Korean J Infect Dis.
  • 2002 Aug;34(4):242-247.
BACKGROUND: Endemic areas of Clonorchis sinensis are in Asia including Korea, China, Taiwan and Vietnam. Its metacercariae consumed in uncooked, or undercooked, unfrozen fish can present human a hazard. Purposes...
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Effects of Nitric Oxide Synthase Inhibitor on Hindlimb Muscles in Rats with Neuropathic Pain Induced by Unilateral Peripheral Nerve Injury

Choe MA, An GJ

PURPOSE: The purpose of this study was to examine effects of nitric oxide synthase (NOS) inhibitor on muscle weight and myofibrillar protein content of affected and unaffected hindlimb muscles in...
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Effect of Anorexia and Neuropathic Pain Induced by Cisplatin on Hindlimb Muscles of Rat

Yang GS, Choe MA

PURPOSE: The purpose of this study was to examine the effect of anorexia and neuropathic pain induced by cisplatin on hindlimb muscles of rats. METHODS: Adult male Sprague-Dawley rats were divided...
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Expression of Glycolysis-Related Proteins in Solid Papillary Carcinoma of the Breast According to Basement Membrane Status

Kwon JE, Jung WH, Koo JS

PURPOSE: The aim of this study was to investigate the differences of expression in glycolysis-related proteins such as Glut-1, carbonic anhydrase (CA) IX, and monocarboxylate transporter (MCT) 4 according to...
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Effects of Different Types of Dietary Fat on Muscle Atrophy According to Muscle Fiber Types and PPARdelta Expression in Hindlimb-Immobilized Rats

Lee HU, Park MN, Lee YS

This study investigated how dietary fat affects muscle atrophy and lipid metabolism in various muscles during hindlimb immobilization in rats. Twenty-four male Sprague-Dawley rats had their left hindlimb immobilized and...
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A 1:1 exercise-to-rest period ratio needed by animals to restore energy sources and replenish anti-oxidative status after exercise

Yeom MY, Cho YO

BACKGROUND/OBJECTIVES: Successful recovery of an animal from exercise is essential, especially prior to the next exercise session. This study was conducted to find an effective exercise-to-rest period ratio for the...
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The Proteomics Approach to Find Biomarkers in Gastric Cancer

Ryu JW, Kim HJ, Lee YS, Myong NH, Hwang CH, Lee GS, Yom HC

Gastric cancer is a very serious disease and is naturally resistant to many anticancer drugs. To reduce the mortality and improve the effectiveness of therapy, many studies have tried to...
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Effects of Isometric Contraction Training by Electrostimulation on Type I and II Hindlimb Muscles in Cerebral Ischemia Model Rats

Lee YK, Choe MA, An GJ

  • KMID: 810626
  • J Korean Acad Nurs.
  • 2006 Dec;36(7):1232-1241.
PURPOSE: The purpose of this study was to examine the effects of cerebral ischemia on Type I(soleus) and Type II(plantaris, gastrocnemius) muscles, and to determine the effects of isometric...
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Dysferlin in a hyperCKaemic patient with caveolin 3 mutation and in C2C12 cells after p38 MAP kinase inhibition

Capanni C, Sabatelli , Mattioli E, Ognibene A, Columbaro , Lattanzi G, Merlini L, Minetti C, Maraldi NM, Squarzoni

  • KMID: 1119336
  • Exp Mol Med.
  • 2003 Dec;35(6):538-544.
Dysferlin is a plasma membrane protein of skeletal muscle whose deficiency causes Miyoshi myopathy, limb girdle muscular dystrophy 2B and distal anterior compartment myopathy. Recent studies have reported that dysferlin...
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