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Multiple Neuroendocrine Tumors in Stomach and Duodenum in a Multiple Endocrine Neoplasia Type 1 Patient

Kim B, Yang HK, Kim WH

A 67-year-old woman with a history of subtotal parathyroidectomy, distal pancreatectomy, and total splenectomy 23 years prior underwent surgical gastric resection for neuroendocrine tumors of the stomach and duodenum. Meticulous...
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Hereditary Aspect of Isolated Familial Acromegaly

Lee WC, Shin MS, Lee KS, Jung N, Huh SK

  • KMID: 1694193
  • J Korean Neurosurg Soc.
  • 1993 Dec;22(12):1309-1318.
Acromegaly is classically considered a sporadic nonfamilial condition. The familial occurance of pituitary adenomas is encountered as a manifestation of the Multiple Endocrine Neoplasia Type I(MEN 1). Moreover in MEN...
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Clinical Manifestation of Multiple Endocrine Neoplasia Type I

Kim YS, Hong SJ

PURPOSE: Multiple endocrine neoplasia type I is rarely reported in Korea. The purpose of this study is to analyze the clinical features and the treatment of MEN1 which had been...
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A case of multiple endocrine neoplasia type 1 with thymic carcinoid tumor

Cho M, Lee KM, Song DH, Ahn CW, Kim KR, Hwang JJ, Baek HC

  • KMID: 2081157
  • Korean J Med.
  • 2005 Oct;69(4):428-433.
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant tumor syndrome. Thymic carcinoid tumors in MEN1 are not common and their natural history is little known. But development of...
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Multiple Pancreatic Islet Cell Tumors with Diverse Hormonal Expression in a Multiple Endocrine Neoplasia Type I Patient: A Case Report

Kim JH, Lee KU, Kim WH, Kim YI

  • KMID: 1979385
  • Korean J Pathol.
  • 2002 Jun;36(3):184-186.
Multiple endocrine neoplasia type I is characterized by multiple tumors, particularly in the parathyroid glands, the pituitary gland and the pancreatic islet. We observed multiple pancreatic islet cell tumors with...
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Multiple Endocrine Neoplasia Type 1 Presenting with an Invasive Giant Prolactinoma

Cha J, Kim JS, Han JS, Park YW, Kim MJ, Ku YH, Kim HI

Pituitary tumors occur in 15-50% of patients with multiple endocrine neoplasia of type 1 (MEN1). To the best of our knowledge, no MEN1 case in which the initial lesion was...
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A Case of Multiple Endocrine Neoplasia Type 1 Combined with Papillary Thyroid Carcinoma

Kim HJ, Park JS, Kim CS, Kang ES, Cha BS, Lim SK, Kim KR, Lee HC, Ahn CW

This is the first report of papillary thyroid carcinoma combined with multiple endocrine neoplasia type 1 (MEN1) in Korea. MEN1 is a hereditary disease comprising neoplastic disorders such as pituitary,...
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A Novel Germline Mutation of MEN1 Gene in a Young-aged Multiple Insulinoma with Hyperparathyroidism

Park YJ

Multiple endocrine neoplasia type 1 is an autosomal dominant disease caused by the MEN1 germline mutation. A 25-year-old male was admitted for loss of consciousness. Initial laboratory data showed hypoglycemia...
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The Characteristics of Multiple Endocrine Neoplasia in Korean

Yang JH, Woo SU

PURPOSE: Multiple Endocrine Neoplasm (MEN) is a rare, complex and familial disease. There are MEN syndromes are inherited in an autosomal dominant fashion with high penetrance. The variations in the...
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A Case of Multiple Endocrine Neoplasia Type 1

Lee DS, Song MH, Kim W, Park IY, Won JM

  • KMID: 2005651
  • J Korean Surg Soc.
  • 1997 Aug;53(2):287-293.
In 1903 Erdheim reported multiple endocrine neoplasia type 1 (MEN 1) by autopsy, and in 1954 Wermer reported a familial occurrence of multiple tumors which were associated with neoplastic transformation...
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Early Symptoms and Clinical Manifestations in Korean Patients with Multiple Endocrine Neoplasia

Kim KH, Koo MY, Hur SM, Lee SK, Choe JH, Lee JE, Kim JS, Chung JH, Nam SJ, Yang JH, Kim JH

PURPOSE: Multiple endocrine neoplasia (MEN) syndrome is an inherited, autosomal dominant disease that presents as a combination of several endocrine tumors. Early diagnosis of this syndrome is difficult, because of...
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A Case of Multiple Endocrine Neoplasia Type 1 with Mutation in MENIN Gene

Park SE, Kang ES, Lee HJ, Kim SH, Do MY, Kang SA, Han SJ, Kim HJ, Ahn CW, Cha BS, Lim SK, Kim KR, Kim IJ, Lee HC

Multiple endocrine neoplasia type 1(MEN 1) is an autosomal dominantly inherited syndrome, characterized by the combined occurrence of tumors of the parathyroid glands, endocrine pancreas, and anterior pituitary gland. The...
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Characteristics of the Germline MEN1 Mutations in Korea: A Literature Review

Lee SC, Min JW, Kim YM, Chang MC

  • KMID: 1709075
  • Korean J Endocr Surg.
  • 2014 Mar;14(1):7-11.
PURPOSE: Multiple endocrine neoplasia type 1 (MEN-1) is an autosomal dominant disease caused by the MEN1 germline mutation. We reviewed previous reports in order to summarize the characteristics of germline...
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Clinical Features of Multiple Endocrine Neoplasia Type I in Koreans

Kim CH, Kim GS, Kim HK, Park JY, Shong YK, Lee KU

  • KMID: 2461618
  • J Korean Soc Endocrinol.
  • 1996 Jun;11(2):163-174.
Background: Multiple endocrine neoplasia type I(MEN I) is a rare, eomplex, and potentially lethal disease. In Korean, only five anecdotal cases were reported as yet. The authors rescently experienced four...
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Pheochromocytoma with pancreatic islet cell tumor: a case report

Ju YT, Jung EJ, Park SH, Hong SC

  • KMID: 2244404
  • Korean J Hepatobiliary Pancreat Surg.
  • 2000 Feb;4(1):191-195.
A 17-years old woman with a combination of unilateral pheochromocytoma and an asymptomatic islet cell tumor of the pancreas is presented. The unusual coincidence of pheochromocytoma and pancreatic islet cell...
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Neuroendocrine Tumors in the Stomach, Duodenum, and Pancreas Accompanied by Novel MEN1 Gene Mutation

Yang MA, Lee WK, Shin HS, Park SH, Kim BS, Kim JW, Cho JW, Yun SH

Multiple endocrine neoplasia type 1 (MEN1) syndrome is a relatively rare disease, characterized by the occurrence of multiple endocrine tumors in the parathyroid and pituitary glands as well as the...
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A Case of Multiple Endocrine Neoplasia Type 1 with Papillary Thyroid Carcinoma

Kim HJ, Kim CS, Je HC, Park J, Park JS, Kong JH, Kang ES, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC, Jang HS, Hong SW

This is the first report of papillary thyroid carcinoma combined with multiple endocrine neoplasia type 1 (MEN 1). It is an hereditary syndrome characterized by neoplastic disorders such as pituitary...
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A Case of Familial Isolated Primary Hyperparathyroidism with a Novel Gene Mutation

Kim SW, Lee SJ, Kim HS, Kim JY, Jung ED, Jung DS

Familial isolated primary hyperparathyroidism (FIHP) is an autosomal dominant disorder that is characterized by an early stage of either multiple endocrine neoplasia type 1 (MEN1) or hyperparathyroidism-jaw tumor (HPT-JT) syndrome....
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Genetic Analysis of Multiple Endocrine Neoplasia Type 1 (MEN1) Leads to Misdiagnosis of an Extremely Rare Presentation of Intrasellar Cavernous Hemangioma as MEN1

Lee DM, Yu SH, Yoon HH, Lee KL, Eom YS, Lee K, Kim BJ, Kim YS, Park IB, Kim KW, Lee S

BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is a rare inherited disorder characterized by the simultaneous occurrence of endocrine tumors in target tissues (mainly the pituitary, endocrine pancreas, and parathyroid...
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Genetic and Epigenetic Analysis in Korean Patients with Multiple Endocrine Neoplasia Type 1

Chung YJ, Hwang S, Jeong JJ, Song SY, Kim SH, Rhee Y

BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is a familial syndrome characterized by the parathyroid, pancreas and pituitary tumors. Parathyroid tumors are the most common clinical manifestations, occurring in more...
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