- Systemic Therapy for Advanced Hepatocellular Carcinoma: Targeted Therapy and Immunotherapy
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Kim BH, Park JW
- KMID: 2409644
- J Liver Cancer.
- 2018 Mar;18(1):17-22.
- doi: 10.17998/jlc.18.1.17
Systemic therapy for hepatocellular carcinoma (HCC) has markedly changed since 2007, with the approval of sorafenib. Sorafenib improved the overall survival of patients with advanced HCC; however, the modest efficacy... -
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- Molecular targeted therapy of thyroid cancer
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Kim SW
- KMID: 2257145
- Korean J Med.
- 2009 Nov;77(5):559-564.
Novel molecular-targeted therapies involving various kinds of kinase inhibitors show promising results in the treatment of advanced thyroid carcinoma refractory to conventional treatment such as surgery and radioiodine treatment. Partial... -
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- Molecular Targeted Therapy in Cancer
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Park HS, Lee NS
- KMID: 2183092
- J Korean Med Assoc.
- 2003 Jun;46(6):542-549.
- doi: 10.5124/jkma.2003.46.6.542
Use of non-selective drugs to kill cancer cells means that healthy cells will inevitably be damaged and many patients will suffer severe side-effects. New therapies are continuously being sought to... -
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- Treatment outcome of radiation therapy and concurrent targeted molecular therapy in spinal metastasis from renal cell carcinoma
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Park S, Kim KH, Rhee WJ, Lee J, Cho Y, Koom WS
- KMID: 2327386
- Radiat Oncol J.
- 2016 Jun;34(2):128-134.
- doi: 10.3857/roj.2016.01718
PURPOSE: To evaluate the clinical outcomes of patients who underwent radiation therapy with or without targeted molecular therapy for the treatment of spinal metastasis from renal cell carcinoma (RCC). MATERIALS AND... -
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- New Strategies for Combined Radioiodine Therapy in Refractory Thyroid Cancer
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Oh SW, Paeng JC, Chung JK
- KMID: 2149618
- J Korean Thyroid Assoc.
- 2015 May;8(1):26-35.
- doi: 10.11106/cet.2015.8.1.26
The prognosis of differentiated thyroid cancer (DTC) is excellent, which is mainly due to the high therapeutic efficacy of radioactive iodine (RAI) therapy as well as indolent nature of thyroid... -
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- Beyond angiogenesis blockade: targeted therapy for advanced cervical cancer
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Eskander R, Tewari KS
- KMID: 2130106
- J Gynecol Oncol.
- 2014 Jul;25(3):249-259.
- doi: 10.3802/jgo.2014.25.3.249
The global burden of advanced stage cervical cancer remains significant, particular in resource poor countries where effective screening programs are absent. Unfortunately, a proportion of patients will be diagnosed with... -
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- Optical Molecular Imaging for Diagnosing Intestinal Diseases
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Kim SY, Myung SJ
- KMID: 2165421
- Clin Endosc.
- 2013 Nov;46(6):620-626.
Real-time visualization of the molecular signature of cells can be achieved with advanced targeted imaging techniques using molecular probes and fluorescence endoscopy. This molecular optical imaging in gastrointestinal endoscopy is... -
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- Recent Update of Molecular Targeted Therapy in Pancreatic Cancer
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Cho JH
- KMID: 1501637
- Korean J Gastroenterol.
- 2013 Mar;61(3):147-154.
- doi: 10.4166/kjg.2013.61.3.147
Pancreatic ductal adenocarcinoma is one of the most dreaded malignancies and the 5th leading cause of cancer-related death in Korea. Late diagnosis and unfavorable response to both chemotherapy and radiotherapy... -
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- Molecular Targeted Therapy for Lung Cancer
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Heo DS
- KMID: 2183064
- J Korean Med Assoc.
- 2003 Jan;46(1):46-50.
- doi: 10.5124/jkma.2003.46.1.46
Lung cancer is a leading cause of cancer deaths in Korea. In spite of some improvements, conventional treatments (surgery, radiotherapy and chemotherapy) did not bring satisfactory solution of this fatal... -
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- Crosstalk Mechanisms Following Targeted Therapy in Head and Neck Cancer
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Byeon HK
- KMID: 2160423
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2016 Mar;59(3):181-187.
- doi: 10.3342/kjorl-hns.2016.59.3.181
Head and neck squamous cell carcinoma has emerged as the sixth most commonly occurring cancer worldwide and despite advances in diagnostics and therapeutics, the treatment results and survival outcomes still... -
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- Personalized Therapy in Lung Cancer: Focused on Molecular Targeted Therapy
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Lee SY, Park JY
- KMID: 2199889
- J Lung Cancer.
- 2011 Jun;10(1):1-12.
- doi: 10.6058/jlc.2011.10.1.1
Lung cancer is the leading cause of cancer death worldwide, with an overall 5 year survival rate of 15%. Most patients present with advanced disease that requires systemic chemotherapy, which... -
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- Present Status and Problems on Molecular Targeted Therapy of Cancer
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Saijo N
- KMID: 2167581
- Cancer Res Treat.
- 2012 Mar;44(1):1-10.
Numerous clinical trials of molecular targeted drugs for cancer have been conducted, with remarkable results for certain drugs and accumulation of "negative data" causing a hitch in the development plan... -
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- Targeted Therapy for Breast Cancer
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Oh HS
- KMID: 2168204
- Hanyang Med Rev.
- 2012 May;32(2):112-117.
- doi: 10.7599/hmr.2012.32.2.112
Breast cancer is the most common cancer in women in the U.S. and Western Europe and second most common cancer in women in Korea. Targeted therapies for breast cancer are... -
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- Molecular Targeted Therapy in Colorectal Cancer
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Yun SH
- KMID: 1835450
- J Korean Soc Coloproctol.
- 2004 Jun;20(3):180-188.
In the last few years, the knowledge of molecular oncology has led to the development of many new biological agents whose targets are extracellular or intracellular molecules involved in the... -
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- Molecular Targeted Therapy in Modern Oncology: Imaging Assessment of Treatment Response and Toxicities
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Krajewski , Braschi-Amirfarzan M, DiPiro PJ, Jagannathan JP, Shinagare
- KMID: 2468120
- Korean J Radiol.
- 2017 Feb;18(1):28-41.
- doi: 10.3348/kjr.2017.18.1.28
Oncology is a rapidly evolving field with a shift toward personalized cancer treatment. The use of therapies targeted to the molecular features of individual tumors and the tumor microenvironment has... -
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- Molecular Targeted Therapy in Lung Cancer
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Ahn MJ
- KMID: 2168312
- Hanyang Med Rev.
- 2014 Feb;34(1):37-44.
- doi: 10.7599/hmr.2014.34.1.37
Lung cancer is the most common cause of cancer death worldwide. With advances in understanding of lung cancer biology and technology, there has been significant improvement in the treatment of... -
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- Drug Therapy for Breast Cancer
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Park YH
- KMID: 2188078
- J Korean Med Assoc.
- 2009 Oct;52(10):963-974.
- doi: 10.5124/jkma.2009.52.10.963
Breast cancer is the second common cancer and the leading cause of cancer deaths in women in Korea. Contrary to public perception, it is a heterogeneous disease with varying morphology,... -
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- Cancer Stem Cells: Biological Features and Targeted Therapeutics
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Song SY, Seo D
- KMID: 2129479
- Hanyang Med Rev.
- 2015 Nov;35(4):250-257.
- doi: 10.7599/hmr.2015.35.4.250
Advance in stem cells (SCs) has become significant by the isolation of the tissue-specific SCs in a tissue, because it is the beginning of using SC utility for regenerative medicine.... -
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- Molecular Targeted Therapy of Head and Neck Cancer: Promising Molecular Targets of Post-Epidermal Growth Factor Receptor Era
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Chang JW, Kim CH
- KMID: 1726623
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2014 Sep;57(9):575-583.
- doi: 10.3342/kjorl-hns.2014.57.9.575
Head and neck squamous cell carcinoma (HNSCC) affects over half a million people worldwide. Despite advances in biology and medicine, only half of the patients are alive in 5 years.... -
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- A Perspective: Role of Targeted Therapy in Colon Cancer
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Chung HH, Jang BI
- KMID: 1501635
- Korean J Gastroenterol.
- 2013 Mar;61(3):128-135.
- doi: 10.4166/kjg.2013.61.3.128
Colorectal cancer is the third most common malignant disease in incidence according to a report in 2009 from Korea. The 5-fluorouracil (5-FU) remains to be a major chemotherapeutic agents. But,... -
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