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Overexpression of Ubiquitin and Amino Acid Permease Genes in Association with Antimony Resistance in Leishmania tropica Field Isolates

Kazemi-Rad E, Mohebali M, Khadem-Erfan MB, Hajjaran H, Hadighi R, Khamesipour A, Rezaie S, Saffari M, Raoofian R, Heidari M

The mainstay therapy against leishmaniasis is still pentavalent antimonial drugs; however, the rate of antimony resistance is increasing in endemic regions such as Iran. Understanding the molecular basis of resistance...
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Visceral Leishmaniasis in Rural Areas of Alborz Province of Iran and Implication to Health Policy

Heidari A, Mohebali M, Kabir K, Barati H, Soultani Y, Keshavarz , Akhoundi B, Hajjaran H, Reisi H

Visceral leishmaniasis (VL) or kala-azar mainly affects children in endemic areas. This study was conducted to determine the seroprevalence of VL using direct agglutination test (DAT) in children living in...
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IgG Avidity ELISA Test for Diagnosis of Acute Toxoplasmosis in Humans

Rahbari AH, Keshavarz , Shojaee S, Mohebali M, Rezaeian M

Serum samples, 100 in the total number, were collected from different laboratories in Tehran, Iran and tested for anti-Toxoplasma specific IgG and IgM antibodies using indirect immunofluorescent antibody test (IFAT)....
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Serologic Tests of IgG and IgM Antibodies and IgG Avidity for Diagnosis of Ocular Toxoplasmosis

Rahimi-Esboei B, Zarei M, Mohebali M, Valian HK, Shojaee S, Mahmoudzadeh R, Salabati M

This prospective study was aimed to detect acute and chronic ocular toxoplasmosis by comparison of anti-Toxoplasma gondii IgM and IgG antibody levels and IgG avidity test. One hundred and seventeen...
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Visceral Leishmaniasis without Fever in an 11-Month-Old Infant: a Rare Clinical Feature of Kala-azar

Sayyahfar , Ansari S, Mohebali M, Behnam B

  • KMID: 1792167
  • Korean J Parasitol.
  • 2014 Apr;52(2):189-191.
Visceral leishmaniasis or kala-azar is an endemic parasitic disease in some parts of the world which is characterized by fever, splenomegaly, and pancytopenia in most of the cases. Herein we...
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First Paleoparasitological Report on the Animal Feces of Bronze Age Excavated from Shahr-e Sukhteh, Iran

Makki M, Dupouy-Camet J, Sajjadi SM, Naddaf SR, Mobedi I, Rezaeian M, Mohebali M, Mowlavi G

Shahr-e Sukhteh (meaning burnt city in Persian) in Iran is an archeological site dated back to around 3,200-1,800 BC. It is located in Sistan and Baluchistan Province of Iran and...
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Production and Evaluation of Toxoplasma gondii Recombinant GRA7 for Serodiagnosis of Human Infections

Selseleh M, Keshavarz , Mohebali M, Shojaee S, Selseleh M, Eshragian , Mansouri F, Modarressi MH

The precise diagnosis of the acute toxoplasmosis in pregnant women and immunocompromsied patients has critical importance. Most of the commercially available assays use the whole Toxoplasma soluble extract as the...
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Real-Time RT-PCR on SAG1 and BAG1 Gene Expression during Stage Conversion in Immunosuppressed Mice Infected with Toxoplasma gondii Tehran Strain

Selseleh M, Modarressi MH, Mohebali M, Shojaee S, Eshragian , Selseleh M, Azizi E, Keshavarz

Toxoplasmic encephalitis is caused by reactivation of bradyzoites to rapidly dividing tachyzoites of the apicomplexan parasite Toxoplasma gondii in immunocompromised hosts. Diagnosis of this life-threatening disease is problematic, because it...
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A Recombinant Plasmodium vivax Apical Membrane Antigen-1 to Detect Human Infection in Iran

Motevalli Haghi A, Khoramizade MR, Nateghpour M, Mohebali M, Edrissian , Eshraghian MR, Sepehrizadeh Z

In Iran, Plasmodium vivax is responsible for more than 80% of the infected cases of malaria per year. Control interventions for vivax malaria in humans rely mainly on developed diagnostic...
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