- Endothelin 1 protects HN33 cells from serum deprivation-induced neuronal apoptosis through Ca2+-PKCalpha-ERK pathway
-
Park MH, Lee DH
- KMID: 1103592
- Exp Mol Med.
- 2008 Feb;40(1):92-97.
- doi: 10.3858/emm.2008.40.1.92
Endothelins (ETs), which were originally found to be potent vasoactive transmitters, were known to be implicated in nervous system, but the mode of mechanism remains unclear. ETs (ET-1, ET-2, and... -
- CITED
-
- Close
- SHARE
-
- Close
- Exposure to Cerium Oxide Nanoparticles Is Associated With Activation of Mitogen-activated Protein Kinases Signaling and Apoptosis in Rat Lungs
-
Rice KM, Nalabotu S, Manne ND, Kolli MB, Nandyala G, Arvapalli , Ma JY, Blough ER
- KMID: 2381462
- J Prev Med Public Health.
- 2015 May;48(3):132-141.
- doi: 10.3961/jpmph.15.006
OBJECTIVES: With recent advances in nanoparticle manufacturing and applications, potential exposure to nanoparticles in various settings is becoming increasing likely. No investigation has yet been performed to assess whether respiratory... -
- CITED
-
- Close
- SHARE
-
- Close
- CD137 induces adhesion and cytokine production in human monocytic THP-1 cells
-
Choi JW, Lee HW, Roh GS, Kim HH, Kwack KB
- KMID: 755745
- Exp Mol Med.
- 2005 Apr;37(2):78-85.
CD137, which is expressed on activated T cells, plays a critical role in inflammatory responses. However, the exact role that CD137 plays in monocytes is not fully known. Here we... -
- CITED
-
- Close
- SHARE
-
- Close
- Protective Effect of Sauchinone Against Regional Myocardial Ischemia/Reperfusion Injury: Inhibition of p38 MAPK and JNK Death Signaling Pathways
-
Kim SJ, Jeong CW, Bae HB, Kwak SH, Son JK, Seo CS, Lee HJ, Lee J, Yoo KY
- KMID: 1372805
- J Korean Med Sci.
- 2012 May;27(5):572-575.
- doi: 10.3346/jkms.2012.27.5.572
Sauchinone has been known to have anti-inflammatory and antioxidant effects. We determined whether sauchinone is beneficial in regional myocardial ischemia/reperfusion (I/R) injury. Rats were subjected to 20 min occlusion of... -
- CITED
-
- Close
- SHARE
-
- Close
- Activated Protein C Protects Myocardium Via Activation of Anti-apoptotic Pathways of Survival in Ischemia-reperfused Rat Heart
-
Ding JW, Tong XH, Yang J, Liu ZQ, Zhang Y, Yang J, Li S, Li L
- KMID: 1779231
- J Korean Med Sci.
- 2010 Nov;25(11):1609-1615.
- doi: 10.3346/jkms.2010.25.11.1609
Activated protein C (APC) is known to be beneficial on ischemia reperfusion injury in myocardium. However, the protection mechanism of APC is not fully understood. The purpose of this study... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Scutellarin on MUC5AC Mucin Production Induced by Human Neutrophil Elastase or Interleukin 13 on Airway Epithelial Cells
-
Jiang DP, Perelman J, Kolosov VP, Zhou XD
- KMID: 1785964
- J Korean Med Sci.
- 2011 Jun;26(6):778-784.
- doi: 10.3346/jkms.2011.26.6.778
Scutellarin is a flavonoid extracted from a traditional Chinese herb, Erigeron breviscapus. The present study investigated the effect of scutellarin on MUC5AC mucin production and the possible mechanism. Human bronchial... -
- CITED
-
- Close
- SHARE
-
- Close
- Bilirubin Activates Transcription of HIF-1alpha in Human Proximal Tubular Cells Cultured in the Physiologic Oxygen Content
-
Kim SG, Ahn SY, Lee ES, Kim S, Na KY, Chae DW, Chin HJ
- KMID: 2069806
- J Korean Med Sci.
- 2014 Sep;29(Suppl 2):S146-S154.
- doi: 10.3346/jkms.2014.29.S2.S146
The expression of hypoxia-inducible factor (HIF) is influenced by reactive oxygen species (ROS). Effect of bilirubin on HIF-1 expression in proximal tubular cells was investigated under physiological oxygen concentration, which... -
- CITED
-
- Close
- SHARE
-
- Close
- p38 MAPK and ERK activation by 9-cis-retinoic acid induces chemokine receptors CCR1 and CCR2 expression in human monocytic THP-1 cells
-
Ko J, Yun CY, Lee JS, Kim JH, Kim IS
- KMID: 1094653
- Exp Mol Med.
- 2007 Apr;39(2):129-138.
9-cis-retinoic acid (9CRA) plays an important role in the immune response; this includes cytokine production and cell migration. We have previously demonstrated that 9CRA increases expression of chemokine receptors CCR1... -
- CITED
-
- Close
- SHARE
-
- Close
- Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model
-
Choi Y, Park SK, Kim HM, Kang JS, Yoon YD, Han SB, Han JW, Yang JS, Han G
- KMID: 1104812
- Exp Mol Med.
- 2008 Oct;40(5):574-581.
- doi: 10.3858/emm.2008.40.5.574
In light of the anti-inflammatory properties of histone deacetylase (HDAC) inhibitors, such as suberoylanilide hydroxamic acid (SAHA) and trichostatin A (TSA), we examined a new HDAC inhibitor KBH-A42 for its... -
- CITED
-
- Close
- SHARE
-
- Close
- Impaired responses of leukemic dendritic cells derived from a human myeloid cell line to LPS stimulation
-
Kim KD, Choi SC, Noh YW, Kim JW, Paik SG, Yang Y, Kim KI, Lim JS
- KMID: 1105279
- Exp Mol Med.
- 2006 Feb;38(1):72-84.
Several myeloid leukemia-derived cells have been reported to possess the ability to differentiate into dendritic cells (DC). MUTZ-3, a myeloid leukemia cell line, responds to GM-CSF, IL-4 and TNF-alpha, and... -
- CITED
-
- Close
- SHARE
-
- Close
