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Prenatal chromosomal microarray analysis of fetus with increased nuchal translucency

Shim SH, Cha DH

Nuchal translucency is an important indicator of an aneuploid fetus in prenatal diagnostics. Previously, only the presence of aneuploid could be confirmed by conventional karyotyping of fetuses with thick nuchal...
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Microarray Analysis on Allergic Inflammation

  • KMID: 2234219
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Dec;24(4):361-367.
It became possible to see all the expressed genes present in a cell (transcriptome) at once using microarray. We have applied microarray technology to various studies regarding allergic diseases. Although...
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Usefulness of Chromosomal Microarray in Hematologic Malignancies: A Case of Aggressive NK-cell Leukemia with 1q Abnormality

Chung YN, Kim HN, Lee SR, Sung HJ, Nam MH

A variety of clonal cytogenetic abnormalities have been reported in aggressive natural killer (NK)-cell lymphoma and leukemia. Recent chromosomal microarray studies have shown both gain and loss of 1q and...
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Analysis of gene expression in placenta of severe preeclampsia

Lee GS, Lee Y, Yang DE, Shin JC

  • KMID: 2280796
  • Korean J Perinatol.
  • 2008 Dec;19(4):341-350.
OBJECTIVE: This study was designed to detect genes specifically expressed in severe preeclamptic placentas. METHODS: Placenta tissues were collected immediately after delivery from 5 preeclamptic patients and 5 normal pregnant women....
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Microarray Analysis of Multiple Gene Expression in Intestinal Metaplasia and Atrophic Gastritis

Choi SR

  • KMID: 1112546
  • Korean J Gastroenterol.
  • 2007 Apr;49(4):260-262.
No abstract availble.
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Big data differential analysis of microglial cell responses in neurodegenerative diseases

Tabassum R, Jeong NY, Chung HJ

Microarray technology has become an indispensable tool for monitoring the levels of gene expression in a given organism through organization, analysis, interpretation, and utilization of biological sequences. Importantly, preliminary microarray...
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Analysis of the Gene Expression by Laser Capture Microdissection (III): Microarray Analysis of the Gene Expression at the Mouse Uterine Luminal Epithelium of the Implantation Sites during Apposition Period1

Yoon SJ, Jeon EH, Park CE, Ko JJ, Choi DH, Cha KY, Kim SN, Lee KA

  • KMID: 1566330
  • Korean J Fertil Steril.
  • 2002 Dec;29(4):323-336.
No abstract available.
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High Throughput Genotyping for Genomic Cohort Study

Park WY

Human Genome Project (HGP) could unveil the secrets of human being by a long script of genetic codes, which enabled us to get access to mine the cause of diseases...
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Microarray Data Analysis of Perturbed Pathways in Breast Cancer Tissues

Kim C, Choi J, Yoon S

  • KMID: 2166421
  • Genomics Inform.
  • 2008 Dec;6(4):210-222.
Due to the polygenic nature of cancer, it is believed that breast cancer is caused by the perturbation of multiple genes and their complex interactions, which contribute to the wide...
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Bannayan-Riley-Ruvalcaba Syndrome in a Patient with a PTEN Mutation Identified by Chromosomal Microarray Analysis: A Case Report

Lee SH, Ryoo E, Tchah H

Bannayan-Riley-Ruvalcaba syndrome (BRRS) is one of the phosphatase and tensin homolog hamartoma tumor syndrome with a PTEN gene mutation. It is a rare dominant autosomal disorder characterized by cutaneous lipomas,...
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Diagnostic distal 16p11.2 deletion in a preterm infant with facial dysmorphism

Hyun JK, Jung YJ

The 16p11.2 microdeletion has been reported in patients with developmental delays and intellectual disability. The distal 220-kb deletion in 16p11.2 is associated with developmental delay, autism spectrum disorder, epilepsy, and...
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Microarray Screening for Genes Involved in Oligodendrocyte Differentiation in the Zebrafish CNS

Chung AY, Kim S, Kim H, Bae YK, Park HC

Within the vertebrate nervous system, myelination is required for the normal function of neurons by facilitating the rapid conduction of action potentials along axons. Oligodendrocytes are glial cells which myelinate...
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Analysis of gene expression during odontogenic differentiation of cultured human dental pulp cells

Seo MS, Hwang KG, Kim H, Baek SH

OBJECTIVES: We analyzed gene-expression profiles after 14 day odontogenic induction of human dental pulp cells (DPCs) using a DNA microarray and sought candidate genes possibly associated with mineralization. MATERIALS AND METHODS:...
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Gene Expression Analysis of Murine Primary Microglia Stimulated with LPS using Microarray

Park JE, Jung D, Han HS

  • KMID: 1626984
  • J Korean Neurol Assoc.
  • 2005 Feb;23(1):77-87.
BACKGROUND: Since heightened microglial activation was shown to play a role in the pathogenesis of many brain disorders, understanding the molecular mechanisms of microglial activation may lead to new treatment...
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Clinical Applications of Chromosomal Microarray Analysis

Seo EJ

  • KMID: 2184475
  • J Genet Med.
  • 2010 Dec;7(2):111-118.
Chromosomal microarray analysis (CMA) enables the genome-wide detection of submicroscopic chromosomal imbalances with greater precision and accuracy. In most other countries, CMA is now a commonly used clinical diagnostic test,...
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Microarray-Based Multivariate Analysis of the Effectiveness of Sublingual Immunotherapy for Cedar Pollinosis

Gotoh M, Kaminuma O, Hiroi T, Okubo K

Sublingual immunotherapy (SLIT) is an effective treatment for allergic diseases. However, the mechanism by which this therapy exhibits its efficacy has not been fully delineated. To elucidate the mechanisms of...
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Microarray Analysis of Gene Expression in Rat Hippocampus of Maternal Social Separation Model

Lee HJ, Son CH, Kwak HR, Lee SH, Han YH, Kim SY, Park JI, Chun W, Kim SS

  • KMID: 2249105
  • Korean J Biol Psychiatry.
  • 2006 May;13(2):110-116.
OBJECTIVES: Alteration of hippocampus was demonstrated in the maternal social separation(MSS) pups, separated from dams on postnatal day(pnd) 14 and placed alone. Therefore, to understand the molecular events involved in...
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Gene Expression Profile in Microglia following Ischemia-Reperfusion Injury

Oh JH, Han HS, Park JS

  • KMID: 1587394
  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):173-180.
Microglial activation is thought to play a role in the pathogenesis of many brain disorders. Therefore, understanding the response of microglia to noxious stimuli may provide insights into their role...
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Microarray Analysis of Oxygen-Glucose-Deprivation Induced Gene Expression in Cultured Astrocytes

Joo DH, Han HS, Park JS

  • KMID: 2071635
  • Korean J Physiol Pharmacol.
  • 2006 Oct;10(5):263-271.
Since astrocytes were shown to play a central role in maintaining neuronal viability both under normal conditions and during stress such as ischemia, studies of the astrocytic response to stress...
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Prediction Model for the Cellular Immortalization and Transformation Potentials of Cell Substrates

Lee MS, Matthews C, Chae MJ, Choi JY, Sohn YW, Kim MJ, Lee SJ, Park WY

  • KMID: 2166238
  • Genomics Inform.
  • 2006 Dec;4(4):161-166.
The establishment of DNA microarray technology has enabled high-throughput analysis and molecular profiling of various types of cancers. By using the gene expression data from microarray analysis we are able...
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