- The effects of high glucose concentration on the synthesis of extracellular matrix and the fine structures of mesangial cells in culture
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Kim JY, Lee YC
- KMID: 1686648
- Korean J Anat.
- 1993 Jun;26(2):167-181.
No abstract available. -
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- The effects of high glucose concentration on phospholipase A2 activity in cultured rat mesangial cells
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Choi KH, Nemenoff R
- KMID: 1694472
- Korean J Nephrol.
- 1993 Dec;12(4):523-532.
No abstract available. -
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- Immune complex-induced increases in collagen production by cultured mesangial cells modulated by dexamthasone and heparin
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Ihm CG, Park JK, Ahn JH, Lee TW, Kim MJ
- KMID: 1694679
- Korean J Nephrol.
- 1992 Oct;11(3):207-213.
No abstract available. -
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- Mechanism of LPS Induced IL-6 Expression in the Growth Arrested Human Mesanigial Cells
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Jin DK
- KMID: 2254734
- Korean J Nephrol.
- 1997 Dec;16(4):642-650.
Mesangial cell proliferation contributes to the development of glomerulonephritis and is associated with glomerulosclerosis. It has been reported that IL-6 is a pluri-potent cytokine which is involved in the mesangial... -
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- Effects of epidermal growth factor and transforming growth factor-?on cultured rat mesangial cells
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Park SK, Kim SB, Yang WS, Park JS, Hong CK, Lee JD, Koh CS
- KMID: 1694607
- Korean J Nephrol.
- 1993 Mar;12(1):1-9.
No abstract available. -
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- Effects of LDL and Oxidized LDL on Mesangial Cell Proliferation and ICAM-1 Expression
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Park W, Kim YH, Park JK, Hong SP, Ahn JH, Lee TW, Ihm CG, Kim MJ
- KMID: 2251547
- Korean J Med.
- 1998 Jul;55(1):104-117.
OBJECTIVES: As one of the studies for the contribution of hyperlipidemia to the pathogenesis of glomerulosclerosis, this study was performed to evaluate the effects of low density lipoprotein(LDL) and oxidized... -
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- Effect of Salicylate on the Monocyte Chemoattractant Protein-1 Expression and Intracellular Reactive Oxygen Species Formation in Human Mesangial Cells
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Kim S
- KMID: 1610143
- Korean J Nephrol.
- 2003 May;22(3):257-260.
No abstract available. -
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- Significance of Urinary Interleukin 6 Level in Mesangial Proliferative Glomerulonephritis in Children
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Kang BH, Kim NH, Chung WY, Kim CH, Lee SY
- KMID: 1879412
- J Korean Pediatr Soc.
- 1994 Jul;37(7):900-905.
By animal experiments in rat, it has been known that Interleukin-6 (IL-6) is secreted from renal mesangial celle and is an autocrine growth factor for the proliferation of mesangial cells.... -
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- LPS-induced Chemokine Gene Expression in Mesangial Cell
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Rim H, Yoon SJ, Park JW
- KMID: 2307275
- Korean J Nephrol.
- 1999 Nov;18(6):847-855.
This study was designed to investigate the mole- cular mechanism of chemokine induction by lipopoly-saccharide(LPS) of E. coli. Chemokine gene expression was evaluated by the reverse transcriptase-polymerase chain reaction(RT-PCR) assay... -
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- Endothelin-1, Endothelin-2 and Endothelin-3 Induced Expression of Monocyte Chemoattractant Protein-1 in Rat Mesangial Cells
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Shin MJ, Kim HW, Yang CW, Kim YS, Kim SY, Choi EJ, Chang YS, Bang BK
- KMID: 1610169
- Korean J Nephrol.
- 2003 Jul;22(4):358-365.
BACKGROUND: Monocyte chemoattractant protein- 1 (MCP-1) is an important mediator for monocyte/ macrophage infiltration in various inflammatory renal diseases and is produced by renal cells. In the process of renal... -
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- The isolation of rabbit glomeruli by iron oxide particle perfusion method and mesangial cell culture
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Lee YC, Hong SP, Kim KH, Chun RW, Chae DW, Noh JW, Shin MK
- KMID: 1694470
- Korean J Nephrol.
- 1993 Dec;12(4):512-522.
No abstract available. -
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- Effects of glucose, insulin and somatostatin on collagen production by glomerular mesangial cell
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Ihm CG, Park JK, Ahn JH, Lee TW, Kim MJ
- KMID: 1694677
- Korean J Nephrol.
- 1992 Oct;11(3):200-206.
No abstract available. -
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- Colocalization of ANG II and mRNA for the Renin-Angiotensin System Components in Cultured Rat Glomerular Epithelial and Mesangial Cells
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Lee WJ, Ko CW, Park MJ
- KMID: 2030746
- Korean J Anat.
- 2002 Apr;35(2):105-111.
Mesangial cells are found to have renin and angiotensin II-AT1 receptors, but the presence of other components of the renin-angiotensin system and production of angiotensin II within the cell have... -
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- Caveolin-1 is involved in high glucose accelerated human glomerular mesangial cell senescence
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Feng X, Gao W, Li Y
- KMID: 2411491
- Korean J Intern Med.
- 2017 Sep;32(5):883-889.
- doi: 10.3904/kjim.2015.254
BACKGROUND/AIMS:: We demonstrated the role of caveolin-1 involved in high glucose (HG)-induced glomerular mesangial cells (GMCs) senescence. METHODS:: HG was used to stimulate GMCs. The telomere lengths were analyzed by Southern... -
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- Effect of Native and Modified Lipoproteins, and Albumin on Human Mesangial Cell Proliferation
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Sohn IS, Lee TW, Park JK, Kim HJ, Cho BS, Ihm CG, Kim MJ
- KMID: 1611210
- Korean J Nephrol.
- 2002 Mar;21(2):266-275.
BACKGROUND: Modified lipoproteins may be involved in nephro- and glomerulosclerosis. Diabetic nephropathy-like lesions have also been induced in a rat model by glycated and glycoxidized albumin. In cultured rat or... -
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- Effects of Troglitazone on the Expression of VEGF and TGF-beta in Cultured Rat Mesangial Cells
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Kim DL, Kim NH, Choi DS
- KMID: 1523010
- J Korean Diabetes Assoc.
- 2007 May;31(3):220-229.
- doi: 10.4093/jkda.2007.31.3.220
BACKGROUND: Clinical study reported that troglitazone ameliorated microalbuminuria in diabetic nephropathy. However, the mechanism of action is not fully understood. Vascular endothelial growth factor (VEGF) is known as vascular permeability... -
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- Over-expression of Liver X Receptor-alpha(LXR alpha by TO901317 Exaggerated the Production of Mesangial Matrix
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Chin HJ, Fu YY, Song YR, Lee ES, Lee YM, Kim SG, Na KY, Kim S, Chae DW
- KMID: 2253063
- Korean J Nephrol.
- 2010 Mar;29(2):189-197.
PURPOSE: To provide the insight into the role of LXR alpha on the progression of diabetic nephropathy, we measured the production of extracellular matrix in the cultured mesangial cells treated... -
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- Aldosterone-induced TGF-beta1 Expression is Regulated by Mitogen-Activated Protein Kinases and Activator Protein-1 in Mesangial Cells
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Han JS, Cho BS, Yang CW, Kim YS
- KMID: 1778162
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S195-S203.
- doi: 10.3346/jkms.2009.24.S1.S195
Aldosterone has been shown to stimulate renal TGF-beta1 expression. However, the mechanisms for aldosterone-induced TGF-beta1 expression have not been clearly determined in mesangial cells. We examined the role of extracellular-signal... -
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- Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma
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Liu Y, Jia L, Liu ZC, Zhang H, Zhang PJ, Wan Q, Wang R
- KMID: 756208
- Exp Mol Med.
- 2009 Sep;41(9):648-655.
- doi: 10.3858/emm.2009.41.9.071
Early stage diabetic nephropathy is characterized by elevated glomerular filtration. Recent studies have identified high-glucose induced p38 MAPK (p38) over-activation in mesangial cells. Mesangial hypocontractility is the major underlying mechanism,... -
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- Mixed or Combined IgA Nephropathy and Membranous Glomerulonephritis
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Yim HE, Hong SW, Kim DH
- KMID: 2254853
- Korean J Nephrol.
- 1997 Jun;16(2):365-368.
We report a rare case of primary glomerular disease with both features of IgA nephropathy and membranous glomerulonephritis in a 45 year-old, HBsAg negative man with nephrotic syndrome. Histologically, glomeruli... -
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