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Dehydroepiandrostrone and Melatonin

Huh KB

  • KMID: 2183037
  • J Korean Med Assoc.
  • 1997 Sep;40(9):1215-1225.
No abstract available.
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Regulation of Melatonin Synthesis and Release in the pineal Gland

Choi BW, Kim KT

  • KMID: 1540193
  • J Korean Soc Endocrinol.
  • 2000 Dec;15(6):708-721.
No Abstract Available.
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Melatonin in Psychiatric Disorders

Lee JS, Kim SG, Kim JH, Jung WY, Park JH

The secretion of melatonin exhibits a circadian rhythm entrained with the sleep-wake cycle. An alteration of this secretory rhythm has been found in various psychiatric disorders. This review summarizes the...
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Changes of the Melatonergic System in Bipolar Disorder: A Literature Review

Lee JH, Moon E

Recently, melatonergic agents have been gaining much interest in the treatment of mood disorders. The elucidation of the underlying biological mechanisms related to the melatonergic system in mood disorders is...
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The Effect of Melatonin on Mouse Jejunal Crypt Cell Survival and Apoptosis

Kang JO, Ha EY, Baik HH, Cho YH, Hong SE

  • KMID: 1769008
  • J Korean Soc Ther Radiol Oncol.
  • 2000 Mar;18(1):59-66.
PURPOSE: To evaluate protective mechanism of melatonin against radiation damage and its relationship with apoptosis in mouse jejunum. MATERIALS AND METHODS:' 168 mice were divided into 28 groups according to...
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Effects of Melatonin on MDPC-23 Cells Differentiation

Park JC, Shin IC, Lee DS, Yoon SH, Yang JH, Kim SB, Kim HJ

  • KMID: 2376071
  • Korean J Phys Anthropol.
  • 2007 Jun;20(2):105-113.
Melatonin is the major hormone released from the pineal gland and regulates a variety of physiological and pathophysiological processes. According to the recent studies the melatonin plays an important role...
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The Relief Effects of Ramelteon on Refractory Chronic Migraine: A Case Report

Hou YC, Lai CH

The selective melatonin receptor agonism effect of ramelteon is useful for insomnia. Here we wanted to present a refractory chronic migraine case, who had significant improvements in migraine after using...
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The Effect of Intravitreal Melatonin on Rabbit Retina

Kim DG, Sohn WS, Kwak HW

  • KMID: 2206162
  • J Korean Ophthalmol Soc.
  • 2002 Sep;43(9):1781-1788.
PURPOSE: To investigate the effect of intravitreal melatonin on retina in rabbit. METHODS: In four pigmented rabbit, melatonin was intravitreally injected 100 mu g/0.1 ml, 300 mu g/0.1 ml concentration in...
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Protective Effect of Melatonin on Neuropathy in Streptozotocin-Induced Diabetic Rats

Kim MO, Jung HY, Paik KW, Lee JK

  • KMID: 2323220
  • J Korean Acad Rehabil Med.
  • 1999 Jun;23(3):449-454.
OBJECTIVE: The purpose of this study is to prove protective action of melatonin on the development of neuropathy in diabetic rat. METHOD: The experimental rats (Sprague-Dawley) were divided into 3 groups:...
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Melatonin Induces Apoptotic Cell Death via p53 in LNCaP Cells

Kim CH, Yoo YM

In this study, we examined whether melatonin promotes apoptotic cell death via p53 in prostate LNCaP cells. Melatonin treatment significantly curtailed the growth of LNCaP cells in a dose- and...
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Changes of TH Immunoreactivities and Melatonin Treatments in the Rat Brain by Chronic Stress

Kim MS

  • KMID: 1564367
  • Korean J Anat.
  • 2005 Aug;38(4):315-324.
These experiments were performed to investigate the effect of saline, melatonin, stress, stressedmelatonin on TH immunoreactivity in rat brain. The animals were injected with melatonin (1 mg/kg, i.p.) after electric...
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Antinociceptive Effects of Intrathecal Melatonin on Formalin: and Thermal-induced Pain in Rats

Chung ST, Jin WJ, Bae HB, Kim SJ, Choi JI, Kang MW, Jeong CY, Yoon MH

BACKGROUND: It has been known that melatonin is involved in the modulation of nociceptive transmission. However, the effect of melatonin administered spinally has not been examined. Therefore, we...
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The Effect of Combination Treatment of Melatonin and Hypothermia on Hypoxic-Ischemic Brain Injury in Neonatal Rats

Park JH, Kim CS, Lee SL, Lee SR

PURPOSE: Melatonin is a naturally occurring hormone produced by the pineal gland. Melatonin has many pharmacological effects in different tissues or organs. Melatonin is especially known to have antioxidant and...
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Melatonin enhances hepatic glutathione-peroxidase activity in Sprague-Dawley rats

Kim CY, Yun CS, Park DH, Choi WS, Kim JS

  • KMID: 1554558
  • Korean J Physiol Pharmacol.
  • 1997 Apr;1(2):221-224.
Effects of melatonin on hepatic glutathione-peroxidase (GSH-Px) and glutathione-reductase (GSH-reductase) activities were studied in Sprague-Dawley (SD) rats administered i.p. (10 mg/kg body weight) with melatonin during 15 days. The activity of cytosolic GSH-reductase...
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The Neuroprotective Effect of Intravitreal Melatonin Injection in Pressure-induced Retinal Ischemia

Lee SJ, Son WS, Kwak HW

  • KMID: 2125071
  • J Korean Ophthalmol Soc.
  • 2001 Apr;42(4):638-646.
PURPOSE: The authors sought to determine the neuroprotective effect of melatonin in a model of ischemic injury in rabbit retina. METHODS: Ischemia was induced by high intraocualr pressure. A dose...
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The Effect of Melatonin on Biochemical Changes after Ischemia-Reperfusion Injury of Rat Skeletal Muscle

Park HJ, Burm JS

  • KMID: 1943205
  • J Korean Soc Plast Reconstr Surg.
  • 2005 Nov;32(6):683-688.
The ischemia-reperfusion injury of the skeletal muscles is caused by generation of reactive oxygen during ischemia and reperfusion. Melatonin or N-Acetyl- 5-methoxy- tryptamine is suggested to have antioxidant effects in...
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The Effects of Melatonin on Postoperative Intraabdominal Adhesion Formation

Hatipoglu , Turkyilmaz Z, Mert S

PURPOSE: Postoperative intraabdominal adhesion formation is a major clinical problem. No previous study was found, reporting the relationship between adhesion formation and melatonin administration, but melatonin, a strong antioxidant, is...
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Melatonin ameliorates autoimmune encephalomyelitis through suppression of intercellular adhesion molecule-1

Kang JC, Ahn M, Kim YS, Moon C, Lee Y, Wie MB, Lee YJ, Shin T

  • KMID: 1103513
  • J Vet Sci.
  • 2001 Aug;2(2):85-89.
Melatonin (N-acetyl-5-methoxytryptamine), a pineal neurohormone, is a hydroxyl radical scavenger and antioxidant, and plays an important role in the immune system. We studied the effect of exogenous melatonin on the...
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The Effect of Sleep Disturbances and Melatonin in Inflammatory Bowel Disease

Park YS

Inflammatory bowel disease (IBD) is an idiopathic condition which increases and decreases in intensity and results in a poor quality of life for those afflicted. Advances in the molecular machinery...
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The Effect of Melatonin on the Gene Expression Profiles of UVB-irradiated Human Skin Fibroblasts related genes.

Song HJ, Lee KS

  • KMID: 1639585
  • Korean J Dermatol.
  • 2006 Mar;44(3):257-266.
BACKGROUND: Ultraviolet B (UVB) irradiation is an important inducer of several biological changes in skin, including sunburn, premature skin aging, and skin cancer, and these changes are mediated mainly by...
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