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The Effects of Hantaan Virus on Fibronectin and Matrix Metalloproteinase-3

Park HS

  • KMID: 1573029
  • J Bacteriol Virol.
  • 2002 Jun;32(2):195-202.
The clinical symptoms and signs of hemorrhagic fever with renal syndrome (HFRS) are well known, but the pathophysiology caused by Hantaan virus is not fully understood yet. This study was...
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Matrix Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-1 levels in Exudative Pleural Effusions

Cho JH, Nam JH, Lee KH, Yoon BK, Ryu JS, Kwak SM, Lee HL

  • KMID: 2318695
  • Tuberc Respir Dis.
  • 2005 Nov;59(5):517-521.
BACKGROUND: The balances of the proteinases and antiproteinases system have been implicated in the pathogenesis of various exudative pleural effusions. The aim of this study was to examine the matrix...
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The Differential expression of matrix metalloproteinase and their tissue inhibitors in myometrium and leiomyoma

Yoo EH, Whang EM, Yu HK, Kim SB

  • KMID: 2261615
  • Korean J Obstet Gynecol.
  • 1999 Dec;42(12):2806-2814.
OBJECTIVES: To determine the level of mRNA expression of various members of the matrix metalloproteinase and tissue inhibitors in uterine leiomyoma compared with unaffected myometrium. Materials & Method: 30 cases of...
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Membrane-type Matrix Metalloproteinase-1 Induced Invasive and Angiogenic Activities in Chick Chorioallantoic Membrane (CAM) Model

Jeong JW, Sohn TK, Yu DY, Kim KW

  • KMID: 2007126
  • J Korean Cancer Assoc.
  • 2001 Feb;33(1):49-55.
PURPOSE: Matrix metalloproteinases (MMPs) have been reported to play critical roles in the endothelial cell migration and matrix remodeling during angiogenic process. To investigate the roles of the membrane type...
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Immunohistochemical study of metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1, -2 in the idiopathic interstitial pneumonia

Kyung SY, Lim YH, An CH, Park JW, Jeong SH, Shin EK, Ha SY, Lee JW

  • KMID: 1620613
  • Korean J Med.
  • 2003 Aug;65(2):196-204.
BACKGROUND: In the idiopathic interstitial pneumonia (IIP), it has been known that imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) is important factor for abnormal remodeling of...
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Changes of Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in Sputum from Moderate to Severe Acute Asthma after Corticosteroid Therapy

Lee JH, Lee JH, Song DY, Baek SH, Kang IJ

  • KMID: 2314400
  • Pediatr Allergy Respir Dis.
  • 2005 Dec;15(4):389-398.
PURPOSE: Bronchial asthma is an inflammatory respiratory disease characterized by the activation of inflammatory cells and its infiltration. It has been recently reported that MMP- 9 dose an importance role...
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Matrix metalloproteinase-9/tissue inhibitor of matrix metalloproteinase-1 in induced sputum of bronchial asthmatics

Kim CW, Kim HJ, Park JW, Hong CS

  • KMID: 1563749
  • J Asthma Allergy Clin Immunol.
  • 2000 Dec;20(6):916-926.
BACKGROUND: Bronchial asthma is a chronic inflammatory disease of the airways characterized by inflammatory cell infiltrations, which require extracellular matrix (ECM) breakdown and inflammatory cell migration. Airway remodeling with ECM...
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Characterization of the cytokine profile of platelet rich plasma (PRP) and PRP-induced cell proliferation and migration: Upregulation of matrix metalloproteinase-1 and -9 in HaCaT cells

Park HB, Yang JH, Chung KH

BACKGROUND: The underlying rationale of platelet rich plasma (PRP) therapy is that an injection of concentrated PRP at the site of injury may promote tissue repair via cytokine release from...
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Expression of Matrix-Metalloproteinase-2, Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Invasion Mode and Lymph Node Metastasis of Laryngeal Squamous Cell Carcinoma

Jin SM, Lee SH, Choi G, Choi JO

  • KMID: 2274480
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Sep;41(9):1169-1173.
BACKGROUND AND OBJECTIVES: Metastatic process of carcinoma cells involves dissolution of tumor matrix and penetration of the basement membrane (BM) which involves the active proteolysis of type IV collagen, proteoglycan,...
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Expression of matrix metalloproteinase-1 and -2 mRNA in retrodiscal tissue of the temporomandibular joint

Huh JK, Park KK, Choi MA, Kim HG

  • KMID: 2137008
  • J Korean Assoc Oral Maxillofac Surg.
  • 2003 Aug;29(4):212-218.
Matrix metalloproteinases (MMPs) play an important role in the normal morphogenesis, maintenance, and repair of matrix and also have important functions in pathologic conditions characterized by excessive degradation of extracellular...
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Effect of Vitamin C, Silicon and Iron on Collagen Synthesis and Break-Down Enzyme Expression in the Human Dermal Fibroblast Cell (HS27)

Kim JE, Lee J, Kim H, Kim J, Cho Y

Collagen is the major matrix protein in dermis and consists of proline and lysine, which are hydroxylated by prolyl hydroxylase (PH) and lysyl hydroxylase (LH) with cofactors such as vitamin...
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Serum Levels of TGF-beta1, TIMP-1 and TIMP-2 in Patients with Lumbar Spinal Stenosis and Disc Herniation

Kim HJ, Park JB, Won HY, Chang H

STUDY DESIGN: The serum levels of transforming growth factor-beta 1 (TGF-beta1), tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) and TIMP-2 were measured by enzyme-linked immunosorbent assay. PURPOSE: To compare the serum...
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Low-dose UVA1 Phototherapy for Localized Scleroderma

Youn NH, Yoo DO, Cha SH, Park SD

  • KMID: 2013655
  • Korean J Dermatol.
  • 2002 May;40(5):551-554.
Localized scleroderma(LS) is sclerosis of the skin characterized by one or multiple circumscribed ivory-white, indurated, sometimes confluent plaques. It has been reported that LS might result from the unbalance between...
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Validation of Gene Expression Changes of Osteopontin and MMP-1 in Primary and Metastatic Colorectal Carcinomas

Choi J, Kim S, Park JH, Kim NK, Kim H

  • KMID: 1837525
  • Korean J Pathol.
  • 2010 Jun;44(3):225-233.
BACKGROUND: Metastasis is one of the most important characteristics of cancer in terms of its impact on patient survival. Unfortunately, identification of altered genes during tumor metastasis is limited. METHODS: Using...
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MMP-1 promoter polymorphism in Korean with generalized aggressive periodontitis

Oh HS, Kim OS, Kim YJ, Chung HJ

  • KMID: 2321653
  • J Korean Acad Periodontol.
  • 2009 Aug;39(Suppl):269-278.
PURPOSE: The aim of this study was to investigate matrix metalloproteinase 1 (MMP-1) gene polymorphism (1G/2G at -1607 and A/G at -519) in Korean subject and to assess the association...
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Expression of Matrix Metalloproteinase (MMP)-1, MMP-3 Nitrotyrosine and Apoptosis in Articular Cartilage of Human Osteoarthritis

Jin SY, Kang SS, Lee DW, Yim SJ, Yun YH, Lee BI

  • KMID: 1725820
  • Korean J Pathol.
  • 2001 Aug;35(4):319-329.
BACKGROUND: Matrix metalloproteinase (MMP)-1 and 3 are the most important degradating enzymes of the chondroid matrix. Chondrocytes may undergo apoptosis under various stimuli including nitric oxide (NO). We studied the...
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The Therapeutic Effect of 5% Imiquimod Cream on Pyogenic Granuloma

Kim SH, Yoon MS, Kim DH

  • KMID: 1640001
  • Korean J Dermatol.
  • 2006 Sep;44(9):1078-1083.
BACKGROUND: Conventional interventions for pyogenic granuloma include excision, electrodessication and curettage, cryotherapy, and laser ablation, all of which can be associated with local tissue destruction, scarring, and recurrence in some...
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The expression of MMP-1, -8, and -13 mRNA in the periodontal ligament of rats during tooth movement with cortical punching

Gwack C, Kim SS, Park SB, Son WS, Kim YD, Jun ES, Park MH

OBJECTIVE: The aim of this study was to determine whether cortical punching stimulates the expression of matrix metalloproteinase-1, -8, and -13 in orthodontic tooth movement in rats. METHODS: A total...
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Effects of H2O2 and ascorbic acid on TIMP-2, Type 1 collagen, and PDLs22 levels in human periodontal ligament fibroblasts

Choi YS, Kim SY, Choi SM, Jang HS, Kim BO

Reactive oxygen species (ROS) have been implicated in the pathogenesis of various diseases. And vitamin C has shown a protective effect for the tissues. The aim of this study was...
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MMP-1 and TIMP-1 production in MG-63 cells stimulated with Prevotella nigrescens lipopolysaccharide

Yang WK, Kim MR, Shon WJ, Lee IB, Cho BH, Um CM, Son HH

The purpose of this study is to monitor the secretion of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) produced by human osteosarcoma cell line (MG63) stimulated with Prevotella...
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